Vertebrate host or tick vector? Which is to blame for Borrelia lusitaniae population structure?
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| Autores principales: | , , , , , , , , , , , , , , , , , |
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Anaerobe
2026
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| _version_ | 1868266084885331969 |
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| author | Norte, Ana Cláudia Carretero, Miguel A da Silva, Luís P Moreno-Rueda, Gregorio Garrido-Bautista, Jorge Zamora-Camacho, Francisco Javier Comas, Mar Gómez-Ramirez, Fernando Rato, Catarina Ramos, Jaime A Rocha, Afonso Laghzaoui, El-Mustapha Megía-Palma, Rodrigo Civantos, Emilio Núncio, M Sofia Lopes de Carvalho, Isabel Fingerle, Volker Margos, Gabriele |
| author_facet | Norte, Ana Cláudia Carretero, Miguel A da Silva, Luís P Moreno-Rueda, Gregorio Garrido-Bautista, Jorge Zamora-Camacho, Francisco Javier Comas, Mar Gómez-Ramirez, Fernando Rato, Catarina Ramos, Jaime A Rocha, Afonso Laghzaoui, El-Mustapha Megía-Palma, Rodrigo Civantos, Emilio Núncio, M Sofia Lopes de Carvalho, Isabel Fingerle, Volker Margos, Gabriele Norte, Ana Cláudia Carretero, Miguel A da Silva, Luís P Moreno-Rueda, Gregorio Garrido-Bautista, Jorge Zamora-Camacho, Francisco Javier Comas, Mar Gómez-Ramirez, Fernando Rato, Catarina Ramos, Jaime A Rocha, Afonso Laghzaoui, El-Mustapha Megía-Palma, Rodrigo Civantos, Emilio Núncio, M Sofia Lopes de Carvalho, Isabel Fingerle, Volker Margos, Gabriele |
| collection | PubMed - marine biology |
| contents | Vertebrate host or tick vector? Which is to blame for Borrelia lusitaniae population structure? Norte, Ana Cláudia Carretero, Miguel A da Silva, Luís P Moreno-Rueda, Gregorio Garrido-Bautista, Jorge Zamora-Camacho, Francisco Javier Comas, Mar Gómez-Ramirez, Fernando Rato, Catarina Ramos, Jaime A Rocha, Afonso Laghzaoui, El-Mustapha Megía-Palma, Rodrigo Civantos, Emilio Núncio, M Sofia Lopes de Carvalho, Isabel Fingerle, Volker Margos, Gabriele Animals Borrelia Phylogeny Ixodes Lizards Multilocus Sequence Typing Spain Genetic Variation Borrelia lusitaniae is a lizard-associated spirochaete which shows highly genetically structured populations in western Europe. Our objective was to assess whether selective forces acting on the Ixodes tick vector or the reservoir lizard, Psammodromus algirus, shaped its population structure. We collected ticks feeding on P. algirus in the Iberian Peninsula and north Africa, and genetically characterized B. lusitaniae, the infected ticks, and the vertebrate host. The goeBURST analysis on seven MLST B. lusitaniae genes identified two main clusters: one from central Europe and other from north Africa and Portugal (south of Tagus river), with some connections between the north Tagus populations in central Spain and north African ones. The Ixodes sp. nuclear gene trospA did not entirely correspond with the B. lusitaniae population structure. The P. algirus's phylogeny based on the ND4 mitochondrial gene also did not show lineage distinctions between north and south Tagus. Both the clustering of B. lusitaniae lineages from this region together with those of south Portugal and north Africa, and the presence of ticks belonging to different trospA clades, suggests Central Spain, a contact area between lineages of P. algirus, as pivotal in the phylogeography of the host, its ticks and Borrelia. |
| format | Artículo científico |
| id | pubmed_41690569 |
| institution | PubMed |
| language | en |
| publishDate | 2026 |
| publisher | Anaerobe |
| record_format | pubmed |
| spellingShingle | Vertebrate host or tick vector? Which is to blame for Borrelia lusitaniae population structure? Norte, Ana Cláudia Carretero, Miguel A da Silva, Luís P Moreno-Rueda, Gregorio Garrido-Bautista, Jorge Zamora-Camacho, Francisco Javier Comas, Mar Gómez-Ramirez, Fernando Rato, Catarina Ramos, Jaime A Rocha, Afonso Laghzaoui, El-Mustapha Megía-Palma, Rodrigo Civantos, Emilio Núncio, M Sofia Lopes de Carvalho, Isabel Fingerle, Volker Margos, Gabriele Animals Borrelia Phylogeny Ixodes Lizards Multilocus Sequence Typing Spain Genetic Variation Vertebrate host or tick vector? Which is to blame for Borrelia lusitaniae population structure? Norte, Ana Cláudia Carretero, Miguel A da Silva, Luís P Moreno-Rueda, Gregorio Garrido-Bautista, Jorge Zamora-Camacho, Francisco Javier Comas, Mar Gómez-Ramirez, Fernando Rato, Catarina Ramos, Jaime A Rocha, Afonso Laghzaoui, El-Mustapha Megía-Palma, Rodrigo Civantos, Emilio Núncio, M Sofia Lopes de Carvalho, Isabel Fingerle, Volker Margos, Gabriele Animals Borrelia Phylogeny Ixodes Lizards Multilocus Sequence Typing Spain Genetic Variation Borrelia lusitaniae is a lizard-associated spirochaete which shows highly genetically structured populations in western Europe. Our objective was to assess whether selective forces acting on the Ixodes tick vector or the reservoir lizard, Psammodromus algirus, shaped its population structure. We collected ticks feeding on P. algirus in the Iberian Peninsula and north Africa, and genetically characterized B. lusitaniae, the infected ticks, and the vertebrate host. The goeBURST analysis on seven MLST B. lusitaniae genes identified two main clusters: one from central Europe and other from north Africa and Portugal (south of Tagus river), with some connections between the north Tagus populations in central Spain and north African ones. The Ixodes sp. nuclear gene trospA did not entirely correspond with the B. lusitaniae population structure. The P. algirus's phylogeny based on the ND4 mitochondrial gene also did not show lineage distinctions between north and south Tagus. Both the clustering of B. lusitaniae lineages from this region together with those of south Portugal and north Africa, and the presence of ticks belonging to different trospA clades, suggests Central Spain, a contact area between lineages of P. algirus, as pivotal in the phylogeography of the host, its ticks and Borrelia. |
| title | Vertebrate host or tick vector? Which is to blame for Borrelia lusitaniae population structure? |
| topic | Animals Borrelia Phylogeny Ixodes Lizards Multilocus Sequence Typing Spain Genetic Variation |
| url | https://pubmed.ncbi.nlm.nih.gov/41690569/ |