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| Main Authors: | , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
eLife
2026
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/41701778/ |
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| _version_ | 1868266084873797632 |
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| author | Jokura, Kei Jasek, Sanja Niederhaus, Lara Burkhardt, Pawel Jékely, Gáspár |
| author_facet | Jokura, Kei Jasek, Sanja Niederhaus, Lara Burkhardt, Pawel Jékely, Gáspár Jokura, Kei Jasek, Sanja Niederhaus, Lara Burkhardt, Pawel Jékely, Gáspár |
| collection | PubMed - marine biology |
| contents | Neural connectome of the ctenophore statocyst. Jokura, Kei Jasek, Sanja Niederhaus, Lara Burkhardt, Pawel Jékely, Gáspár Animals Connectome Ctenophora Volume Electron Microscopy Neurons Cilia Gravity Sensing Nerve Net Ctenophores possess a unique gravity receptor (statocyst) in their aboral organ formed by four clusters of ciliated balancer cells that collectively support a statolith. During reorientation, differential loads on the balancer cilia lead to altered beating of the ciliated comb rows to elicit turns. To study the neural bases of gravity sensing, we used volume electron microscopy to image the aboral organ of the ctenophore . We reconstructed 1011 cells, including syncytial neurons that form a nerve net. The syncytial neurons synapse on the balancer cells and also form reciprocal connections with the bridge cells that span the statocyst. High-speed imaging revealed that balancer cilia beat and arrest in a coordinated manner but with differences between the sagittal and tentacular planes of the animal, reflecting nerve-net organization. Our results suggest a coordinating rather than sensory-motor function for the nerve net and inform our understanding of the diversity of nervous-system organization across animals. |
| format | Artículo científico |
| id | pubmed_41701778 |
| institution | PubMed |
| language | en |
| publishDate | 2026 |
| publisher | eLife |
| record_format | pubmed |
| spellingShingle | Neural connectome of the ctenophore statocyst. Jokura, Kei Jasek, Sanja Niederhaus, Lara Burkhardt, Pawel Jékely, Gáspár Animals Connectome Ctenophora Volume Electron Microscopy Neurons Cilia Gravity Sensing Nerve Net Neural connectome of the ctenophore statocyst. Jokura, Kei Jasek, Sanja Niederhaus, Lara Burkhardt, Pawel Jékely, Gáspár Animals Connectome Ctenophora Volume Electron Microscopy Neurons Cilia Gravity Sensing Nerve Net Ctenophores possess a unique gravity receptor (statocyst) in their aboral organ formed by four clusters of ciliated balancer cells that collectively support a statolith. During reorientation, differential loads on the balancer cilia lead to altered beating of the ciliated comb rows to elicit turns. To study the neural bases of gravity sensing, we used volume electron microscopy to image the aboral organ of the ctenophore . We reconstructed 1011 cells, including syncytial neurons that form a nerve net. The syncytial neurons synapse on the balancer cells and also form reciprocal connections with the bridge cells that span the statocyst. High-speed imaging revealed that balancer cilia beat and arrest in a coordinated manner but with differences between the sagittal and tentacular planes of the animal, reflecting nerve-net organization. Our results suggest a coordinating rather than sensory-motor function for the nerve net and inform our understanding of the diversity of nervous-system organization across animals. |
| title | Neural connectome of the ctenophore statocyst. |
| topic | Animals Connectome Ctenophora Volume Electron Microscopy Neurons Cilia Gravity Sensing Nerve Net |
| url | https://pubmed.ncbi.nlm.nih.gov/41701778/ |