From Multi-Species Screening to Targeted Investigation: Discovery of ACE Inhibitory Peptides in via Peptidomics, Virtual Screening, and Molecular Dynamics Simulations.
Fuente:
PubMed
Enregistré dans:
| Auteurs principaux: | Zhang, Haorui, Ouyang, Yuhong, Suo, Qishan, Chen, Hao, Cui, Jie, Yue, Yang |
|---|---|
| Format: | Artículo científico |
| Langue: | en |
| Publié: |
Molecules (Basel, Switzerland)
2026
|
| Sujets: | |
| Accès en ligne: | |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
The Antioxidant Effects of Trypsin-Hydrolysate Derived from Abalone Viscera and Fishery By-Products, and the Angiotensin-I Converting Enzyme (ACE) Inhibitory Activity of Its Purified Bioactive Peptides.
par: Heo, Jun-Ho, et autres
Publié: (2024)
par: Heo, Jun-Ho, et autres
Publié: (2024)
Discovery and molecular mechanism of a novel antihypertensive peptide from Chlamydomonas reinhardtii based on molecular docking, molecular dynamics simulation, in vitro, and in vivo analysis.
par: Suo, Qishan, et autres
Publié: (2026)
par: Suo, Qishan, et autres
Publié: (2026)
Identification and anticoagulant mechanisms of novel factor XIa inhibitory peptides by virtual screening of a in silico generated deep-sea peptide database.
par: Ouyang, Yuhong, et autres
Publié: (2024)
par: Ouyang, Yuhong, et autres
Publié: (2024)
Quantitative Structure-Activity Relationship and Molecular Modeling Studies on a Series of Hydroxypyrrolo[2,1-c][1,4]Benzodiazepine-5,11-dione Acting as Angiotensin Converting Enzyme I Inhibitors
par: Sanober, Ayesha, et autres
Publié: (2021)
par: Sanober, Ayesha, et autres
Publié: (2021)
Anticoagulant and angiotensin-converting enzyme inhibitory activities of a fucoidan from and its low molecular weight fragments prepared by acid degradation.
par: Liu, Xue, et autres
Publié: (2026)
par: Liu, Xue, et autres
Publié: (2026)
Unveiling an indole derivative YM818 as a novel tyrosinase inhibitor with anti-melanogenic and anti-melanin transfer effects.
par: Yang, Chunyan, et autres
Publié: (2025)
par: Yang, Chunyan, et autres
Publié: (2025)
Computational screening of natural plant and marine compounds as potential inhibitors of Mycobacterium tuberculosis dihydrodipicolinate synthase.
par: Meena, Swati, et autres
Publié: (2026)
par: Meena, Swati, et autres
Publié: (2026)
Establishment of an efficient structure-based protein clustering strategy to discovery the galactose 4-O-sulfotransferases with unexplored structural features.
par: Chen, Wencui, et autres
Publié: (2025)
par: Chen, Wencui, et autres
Publié: (2025)
Identification of Antioxidant and Anti-Inflammatory Activity of Sea Cucumber () Active Peptides by a Combined Approach of Omics Data and Bioinformatics Analysis.
par: La Paglia, Laura, et autres
Publié: (2026)
par: La Paglia, Laura, et autres
Publié: (2026)
Diverse and Bioactive Lactones from the Sri Lankan Mangrove-Derived Fungus sp. SCSIO41445.
par: Wijerathna, Parakkrama, et autres
Publié: (2026)
par: Wijerathna, Parakkrama, et autres
Publié: (2026)
Mechanistic insights into profenofos interactions with antioxidant enzymes in Labeo rohita.
par: Naz, Saima, et autres
Publié: (2026)
par: Naz, Saima, et autres
Publié: (2026)
Potential of Marine Bacterial Metalloprotease A69 in the Preparation of Antarctic Krill Peptides with Multi-Bioactivities.
par: Liu, Rui, et autres
Publié: (2025)
par: Liu, Rui, et autres
Publié: (2025)
The heat shock transcription factor regulates the expression of crustin in Portunus trituberculatus.
par: Wu, Yijing, et autres
Publié: (2026)
par: Wu, Yijing, et autres
Publié: (2026)
Computer-aided screening of marine fungal metabolites as potential inhibitors of new Delhi metallo-beta-lactamase-1.
par: Shabbir, Farhat, et autres
Publié: (2025)
par: Shabbir, Farhat, et autres
Publié: (2025)
Isolation and Purification of Novel Antioxidant Peptides from Mussel () Prepared by Marine Z-1 Protease.
par: Lu, Jing, et autres
Publié: (2025)
par: Lu, Jing, et autres
Publié: (2025)
Effects of Octacosanol Isolated from Leaves on Inhibiting the Activity of Pancreatic Lipase.
par: Dong, Xiaoying, et autres
Publié: (2025)
par: Dong, Xiaoying, et autres
Publié: (2025)
Novel peptide inhibitor of matrix Metalloproteinases-1 from pufferfish skin collagen hydrolysates and its potential Photoprotective activity via the MAPK/AP-1 signaling pathway.
par: Chen, Bei, et autres
Publié: (2025)
par: Chen, Bei, et autres
Publié: (2025)
Optimized ebselen derivatives as novel potent Escherichia coli β-glucuronidase covalent allosteric inhibitors.
par: Ying, Ti-Ti, et autres
Publié: (2025)
par: Ying, Ti-Ti, et autres
Publié: (2025)
Binding Stability and Catalytic Mechanism of a Novel Chitin Deacetylase from and Preparation of Chitosan.
par: Liang, Bicheng, et autres
Publié: (2025)
par: Liang, Bicheng, et autres
Publié: (2025)
Molecular Docking and Dynamics Simulations Reveal the Antidiabetic Potential of a Novel Fucoxanthin Derivative from .
par: Sigera, Sachini, et autres
Publié: (2025)
par: Sigera, Sachini, et autres
Publié: (2025)
Computational analysis of zoanthamine alkaloids from Zoanthus sp. as potential DKK1 and GSK-3β inhibitors for osteoporosis therapy via Wnt signaling.
par: Pham, Ngoc-Thac, et autres
Publié: (2025)
par: Pham, Ngoc-Thac, et autres
Publié: (2025)
Evaluating the estrogen degradation potential of laccase and peroxidase from Bacillus ligniniphilus L1 through integrated computational and experimental approaches.
par: Nawaz, Muhammad Zohaib, et autres
Publié: (2024)
par: Nawaz, Muhammad Zohaib, et autres
Publié: (2024)
Kingdom-specific lipid unsaturation calibrates sequence evolution in membrane arm subunits of eukaryotic respiratory complexes.
par: Gupta, Pooja, et autres
Publié: (2025)
par: Gupta, Pooja, et autres
Publié: (2025)
Decoding the multifunctional potential of ursolic acid: antioxidant, antiproliferative, molecular dynamics, and biodegradability evaluations of a mangrove-derived terpenoid.
par: Parthiban, Anaikutti, et autres
Publié: (2025)
par: Parthiban, Anaikutti, et autres
Publié: (2025)
Proteinaceous Toxins in the Mucus and Proboscis of the Ribbon Worm cf. (Palaeonemertea: Nemertea).
par: Kuznetsov, Vasiliy G, et autres
Publié: (2025)
par: Kuznetsov, Vasiliy G, et autres
Publié: (2025)
Identification of Marine Compounds Inhibiting NF-κBInducing Kinase Through Molecular Docking and Molecular Dynamics Simulations.
par: Yasir, Muhammad, et autres
Publié: (2024)
par: Yasir, Muhammad, et autres
Publié: (2024)
A fish-specific antimicrobial peptide Piscidin2 inactivates MSRV and confers protection in largemouth bass.
par: Fei, Chenjie, et autres
Publié: (2025)
par: Fei, Chenjie, et autres
Publié: (2025)
The NeuroImmunoEndocrine Circuit of Umami Peptides: A Systems Biology Approach.
par: Hemmati, Shiva, et autres
Publié: (2026)
par: Hemmati, Shiva, et autres
Publié: (2026)
Structural and functional insights into glycosyltransferase from Nocardia asteroides NCTC11293 and structure-guided discovery of marine and phytochemical leads through pharmacokinetic screening and molecular dynamics studies.
par: Muthuvairam Subbulakshmi, Maharaja, et autres
Publié: (2026)
par: Muthuvairam Subbulakshmi, Maharaja, et autres
Publié: (2026)
Structure-guided discovery of marine natural products as glucokinase activators for type 2 diabetes mellitus: A computational perspective.
par: Krishnakumar, Heyram, et autres
Publié: (2026)
par: Krishnakumar, Heyram, et autres
Publié: (2026)
Stereoselective AChE/BChE/BACE1 inhibition by enantiomeric norsesquiterpenoids with an unprecedented oxatricyclo[7.2.1.0]dodecane scaffold from the soft coral Sclerophytum humesi.
par: Luu, Phuong Vu, et autres
Publié: (2026)
par: Luu, Phuong Vu, et autres
Publié: (2026)
Conkazal-M1 from the MKAVA family of conotoxins: A dual-function protease inhibitor and neuroactive peptide.
par: Hackney, Celeste M, et autres
Publié: (2026)
par: Hackney, Celeste M, et autres
Publié: (2026)
MolluscDB 2.0: a comprehensive functional and evolutionary genomics database for over 1400 molluscan species.
par: Liu, Fuyun, et autres
Publié: (2025)
par: Liu, Fuyun, et autres
Publié: (2025)
Screening and Interaction Analysis of Shark-Derived Nanobodies against Crayfish Major Allergen Pro c 2.
par: Yang, Yang, et autres
Publié: (2025)
par: Yang, Yang, et autres
Publié: (2025)
Data-Independent Acquisition-Based Quantitative Proteomics, Nontargeted Metabolomics, and Protein-Ligand Interaction Reveal the Mechanism of Baicalin Inhibiting βhemolytic/cytolytic Activities of .
par: Li, Guihua, et autres
Publié: (2026)
par: Li, Guihua, et autres
Publié: (2026)
Proteomics of the shell matrix proteins and functional analysis of Am13 and AmKaSPI from the shell of Archivesica marissinica.
par: Liu, Dongting, et autres
Publié: (2025)
par: Liu, Dongting, et autres
Publié: (2025)
Identification, Screening and Mechanism Analysis of Anti-Parkinson's Disease Peptides from Protein Hydrolysates.
par: Wang, Qingzhong, et autres
Publié: (2026)
par: Wang, Qingzhong, et autres
Publié: (2026)
Revelation of Brevi-inflammin, a novel anti-inflammatory metabolite from Brevibacterium casei VRK 1, as a potent COX-2 inhibitor.
par: Chandrasekaran, Vishnupriya, et autres
Publié: (2025)
par: Chandrasekaran, Vishnupriya, et autres
Publié: (2025)
Morphological and functional response of Mytilus galloprovincialis exposed to the Enalapril metabolite, Enalaprilat.
par: Caferro, Alessia, et autres
Publié: (2025)
par: Caferro, Alessia, et autres
Publié: (2025)
Hybrid Computational Framework Integrating Ensemble Learning, Molecular Docking, and Dynamics for Predicting Antimalarial Efficacy of Malaria Box Compounds.
par: Moreno, Martín, et autres
Publié: (2026)
par: Moreno, Martín, et autres
Publié: (2026)
Documents similaires
-
The Antioxidant Effects of Trypsin-Hydrolysate Derived from Abalone Viscera and Fishery By-Products, and the Angiotensin-I Converting Enzyme (ACE) Inhibitory Activity of Its Purified Bioactive Peptides.
par: Heo, Jun-Ho, et autres
Publié: (2024) -
Discovery and molecular mechanism of a novel antihypertensive peptide from Chlamydomonas reinhardtii based on molecular docking, molecular dynamics simulation, in vitro, and in vivo analysis.
par: Suo, Qishan, et autres
Publié: (2026) -
Identification and anticoagulant mechanisms of novel factor XIa inhibitory peptides by virtual screening of a in silico generated deep-sea peptide database.
par: Ouyang, Yuhong, et autres
Publié: (2024) -
Quantitative Structure-Activity Relationship and Molecular Modeling Studies on a Series of Hydroxypyrrolo[2,1-c][1,4]Benzodiazepine-5,11-dione Acting as Angiotensin Converting Enzyme I Inhibitors
par: Sanober, Ayesha, et autres
Publié: (2021) -
Anticoagulant and angiotensin-converting enzyme inhibitory activities of a fucoidan from and its low molecular weight fragments prepared by acid degradation.
par: Liu, Xue, et autres
Publié: (2026)