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| Autores principales: | , , , , , , , , , |
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| Formato: | Artículo científico |
| Lenguaje: | en |
| Publicado: |
Animals : an open access journal from MDPI
2026
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| Acceso en línea: | https://pubmed.ncbi.nlm.nih.gov/41829037/ |
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Tabla de Contenidos:
- Clinical and Epidemiological Features of Calicivirus Infections in Cattle. Bányai, Krisztián Ndze, Valantine Ngum Bogdán, Ágnes Kiss, Attila Tóth, Tamás Lanszki, Zsófia Lanave, Gianvito Pellegrini, Francesco Di Martino, Barbara Martella, Vito The family encompasses a diverse group of non-enveloped, positive-sense RNA viruses that are significant pathogens in veterinary medicine. This narrative review summarizes the current state of knowledge regarding the clinical, molecular, and epidemiological features of the three calicivirus genera identified in bovine hosts: , , and . Bovine noroviruses and neboviruses are neglected enteric pathogens, frequently detected in association with neonatal calf diarrhea and often present in co-infections with other enteric agents. Clinical presentations for these enteric viruses range from severe, watery diarrhea to asymptomatic shedding, with distinct pathogenic profiles observed between norovirus genotypes GIII.1 and GIII.2. In contrast, the genus exhibits a broad host range, and bovine vesivirus strains are phylogenetically linked to vesiviruses identified in pigs and marine animals. Bovine vesivirus infections are associated with a broader spectrum of clinical manifestations, including respiratory disease, vesicular lesions, and abortion. Serological and virological surveys indicate that exposure to these viruses is ubiquitous in cattle populations globally. While direct evidence of human infection by bovine noroviruses and neboviruses remains limited, vesiviruses possess a confirmed capacity for cross-species transmission to humans. Significant knowledge gaps remain, particularly regarding in vitro culture systems, necessitating further research to facilitate vaccine development and clarify transmission dynamics.