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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Artículo científico |
| Langue: | en |
| Publié: |
Nature communications
2026
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| Sujets: | |
| Accès en ligne: | https://pubmed.ncbi.nlm.nih.gov/41932893/ |
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| _version_ | 1868266064373088256 |
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| author | Liang, Jeffrey Cahier, Karine Piel, Damien Cueva Granda, Dario Goudenège, David Labreuche, Yannick Ma, Laurence Monot, Marc Bernard, Charles Rocha, Eduardo P C Le Roux, Frédérique |
| author_facet | Liang, Jeffrey Cahier, Karine Piel, Damien Cueva Granda, Dario Goudenège, David Labreuche, Yannick Ma, Laurence Monot, Marc Bernard, Charles Rocha, Eduardo P C Le Roux, Frédérique Liang, Jeffrey Cahier, Karine Piel, Damien Cueva Granda, Dario Goudenège, David Labreuche, Yannick Ma, Laurence Monot, Marc Bernard, Charles Rocha, Eduardo P C Le Roux, Frédérique |
| collection | PubMed - marine biology |
| contents | Complex temporal dynamics of phage-bacteria populations in an animal-associated marine system. Liang, Jeffrey Cahier, Karine Piel, Damien Cueva Granda, Dario Goudenège, David Labreuche, Yannick Ma, Laurence Monot, Marc Bernard, Charles Rocha, Eduardo P C Le Roux, Frédérique Animals Bacteriophages Vibrio Ostreidae Phylogeny Gene Transfer, Horizontal Genome, Viral Genetic Variation Prophages Lysogeny Bacteriophages-bacteria interactions drive rapid evolution of both partners in laboratory studies. To understand how these dynamics unfold in natural environments, we re-sampled a population of Vibrio crassostreae and their phages in an open, animal-associated marine system four years apart. Analysis of over 1000 predominantly virulent phages revealed rapid change of some lineages, but persistence of others, with genomes highly conserved between years. This pattern is consistent with low substitution rates in persistent lineages and may reflect phages overwintering in wild oysters, slow virion decay, and for temperate phages, lysogeny within hosts. Over 600 V. crassostreae strains recovered at both time points assorted into the same major clades. Oyster-associated vibrios have larger genomes and more abundant and diverse mobile genetic elements suggesting that oysters are hotspots for genetic exchange and horizontal gene transfer. Their genomes encode virulence plasmids, prophages carrying anti-phage systems, phage-plasmids, and phage satellites that persist intracellularly as plasmids. Time series analyses revealed weak correlations between phage and bacterial abundances, a pattern compatible with cryptic population dynamics arising from genetic diversity. Together, these results indicate that natural coevolving phage-bacteria populations can exhibit complex dynamics, with rapid replacement of some lineages alongside multi-year persistence of others. |
| format | Artículo científico |
| id | pubmed_41932893 |
| institution | PubMed |
| language | en |
| publishDate | 2026 |
| publisher | Nature communications |
| record_format | pubmed |
| spellingShingle | Complex temporal dynamics of phage-bacteria populations in an animal-associated marine system. Liang, Jeffrey Cahier, Karine Piel, Damien Cueva Granda, Dario Goudenège, David Labreuche, Yannick Ma, Laurence Monot, Marc Bernard, Charles Rocha, Eduardo P C Le Roux, Frédérique Animals Bacteriophages Vibrio Ostreidae Phylogeny Gene Transfer, Horizontal Genome, Viral Genetic Variation Prophages Lysogeny Complex temporal dynamics of phage-bacteria populations in an animal-associated marine system. Liang, Jeffrey Cahier, Karine Piel, Damien Cueva Granda, Dario Goudenège, David Labreuche, Yannick Ma, Laurence Monot, Marc Bernard, Charles Rocha, Eduardo P C Le Roux, Frédérique Animals Bacteriophages Vibrio Ostreidae Phylogeny Gene Transfer, Horizontal Genome, Viral Genetic Variation Prophages Lysogeny Bacteriophages-bacteria interactions drive rapid evolution of both partners in laboratory studies. To understand how these dynamics unfold in natural environments, we re-sampled a population of Vibrio crassostreae and their phages in an open, animal-associated marine system four years apart. Analysis of over 1000 predominantly virulent phages revealed rapid change of some lineages, but persistence of others, with genomes highly conserved between years. This pattern is consistent with low substitution rates in persistent lineages and may reflect phages overwintering in wild oysters, slow virion decay, and for temperate phages, lysogeny within hosts. Over 600 V. crassostreae strains recovered at both time points assorted into the same major clades. Oyster-associated vibrios have larger genomes and more abundant and diverse mobile genetic elements suggesting that oysters are hotspots for genetic exchange and horizontal gene transfer. Their genomes encode virulence plasmids, prophages carrying anti-phage systems, phage-plasmids, and phage satellites that persist intracellularly as plasmids. Time series analyses revealed weak correlations between phage and bacterial abundances, a pattern compatible with cryptic population dynamics arising from genetic diversity. Together, these results indicate that natural coevolving phage-bacteria populations can exhibit complex dynamics, with rapid replacement of some lineages alongside multi-year persistence of others. |
| title | Complex temporal dynamics of phage-bacteria populations in an animal-associated marine system. |
| topic | Animals Bacteriophages Vibrio Ostreidae Phylogeny Gene Transfer, Horizontal Genome, Viral Genetic Variation Prophages Lysogeny |
| url | https://pubmed.ncbi.nlm.nih.gov/41932893/ |