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Main Authors: Paolella, Giulia, Yao, Sicong, Fabbricino, Massimiliano, Locascio, Annamaria, Rosati, Luigi, Pontoni, Ludovico, Sirakov, Maria
Format: Artículo científico
Language:en
Published: Marine pollution bulletin 2026
Subjects:
Online Access:https://pubmed.ncbi.nlm.nih.gov/41962300/
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author Paolella, Giulia
Yao, Sicong
Fabbricino, Massimiliano
Locascio, Annamaria
Rosati, Luigi
Pontoni, Ludovico
Sirakov, Maria
author_facet Paolella, Giulia
Yao, Sicong
Fabbricino, Massimiliano
Locascio, Annamaria
Rosati, Luigi
Pontoni, Ludovico
Sirakov, Maria
Paolella, Giulia
Yao, Sicong
Fabbricino, Massimiliano
Locascio, Annamaria
Rosati, Luigi
Pontoni, Ludovico
Sirakov, Maria
collection PubMed - marine biology
contents Evaluation of tissue-specific Bisphenol A accumulation in mussels upon acute exposure: A pilot study. Paolella, Giulia Yao, Sicong Fabbricino, Massimiliano Locascio, Annamaria Rosati, Luigi Pontoni, Ludovico Sirakov, Maria Animals Phenols Bisphenol A Compounds Benzhydryl Compounds Water Pollutants, Chemical Mytilus Pilot Projects Environmental Monitoring Gills Tissue-specific accumulation of Bisphenol A is evaluated for the first time in the mussel Mytilus galloprovincialis to trace the contaminant path within the selected tissues. Evaluation occurred in Mantle, Gills and Digestive gland after acute exposure to concentrations of the contaminant ranging from 6,25 to 125 ppb. Different uptakes were detected depending on the Bisphenol A exposure concentration: specifically, at low Bisphenol A doses (from 0 to 12.5 ppb) no substantial differences were observed among Mantle, Gills and Digestive gland. Starting from 31.25 ppb of Bisphenol A exposure, higher uptake in the Mantle was detected (up to 116.0 μg/g dry weight) and morphological alteration of reproductive organs was observed. The results obtained, supported by histological analysis, provided novel insights into the pathways of Bisphenol A bioaccumulation and the variability of tissue-level responses. Overall, this integrated strategy offers a powerful tool to investigate contaminant dynamics, paving the way to a deeper understanding of long-term effects and supporting more effective risk assessment and environmental regulation.
format Artículo científico
id pubmed_41962300
institution PubMed
language en
publishDate 2026
publisher Marine pollution bulletin
record_format pubmed
spellingShingle Evaluation of tissue-specific Bisphenol A accumulation in mussels upon acute exposure: A pilot study.
Paolella, Giulia
Yao, Sicong
Fabbricino, Massimiliano
Locascio, Annamaria
Rosati, Luigi
Pontoni, Ludovico
Sirakov, Maria
Animals
Phenols
Bisphenol A Compounds
Benzhydryl Compounds
Water Pollutants, Chemical
Mytilus
Pilot Projects
Environmental Monitoring
Gills
Evaluation of tissue-specific Bisphenol A accumulation in mussels upon acute exposure: A pilot study. Paolella, Giulia Yao, Sicong Fabbricino, Massimiliano Locascio, Annamaria Rosati, Luigi Pontoni, Ludovico Sirakov, Maria Animals Phenols Bisphenol A Compounds Benzhydryl Compounds Water Pollutants, Chemical Mytilus Pilot Projects Environmental Monitoring Gills Tissue-specific accumulation of Bisphenol A is evaluated for the first time in the mussel Mytilus galloprovincialis to trace the contaminant path within the selected tissues. Evaluation occurred in Mantle, Gills and Digestive gland after acute exposure to concentrations of the contaminant ranging from 6,25 to 125 ppb. Different uptakes were detected depending on the Bisphenol A exposure concentration: specifically, at low Bisphenol A doses (from 0 to 12.5 ppb) no substantial differences were observed among Mantle, Gills and Digestive gland. Starting from 31.25 ppb of Bisphenol A exposure, higher uptake in the Mantle was detected (up to 116.0 μg/g dry weight) and morphological alteration of reproductive organs was observed. The results obtained, supported by histological analysis, provided novel insights into the pathways of Bisphenol A bioaccumulation and the variability of tissue-level responses. Overall, this integrated strategy offers a powerful tool to investigate contaminant dynamics, paving the way to a deeper understanding of long-term effects and supporting more effective risk assessment and environmental regulation.
title Evaluation of tissue-specific Bisphenol A accumulation in mussels upon acute exposure: A pilot study.
topic Animals
Phenols
Bisphenol A Compounds
Benzhydryl Compounds
Water Pollutants, Chemical
Mytilus
Pilot Projects
Environmental Monitoring
Gills
url https://pubmed.ncbi.nlm.nih.gov/41962300/