Enhancement of Orthodontic Tooth Movement by Oral Administration of Pangasius hypophthalmus Oil: An in Vivo Study.
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| Main Authors: | , , , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
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Orthodontics & craniofacial research
2026
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| _version_ | 1868266061984432129 |
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| author | Lubis, Hilda Fitria Idrus, Erik Sastradipura, Dewi Fatma Suniarti Suseno, Sugeng Heri Widayati, Retno Amir, Lisa Rinanda Bahtiar, Anton Jazaldi, Fadli Wulandari, Pitu |
| author_facet | Lubis, Hilda Fitria Idrus, Erik Sastradipura, Dewi Fatma Suniarti Suseno, Sugeng Heri Widayati, Retno Amir, Lisa Rinanda Bahtiar, Anton Jazaldi, Fadli Wulandari, Pitu Lubis, Hilda Fitria Idrus, Erik Sastradipura, Dewi Fatma Suniarti Suseno, Sugeng Heri Widayati, Retno Amir, Lisa Rinanda Bahtiar, Anton Jazaldi, Fadli Wulandari, Pitu |
| collection | PubMed - marine biology |
| contents | Enhancement of Orthodontic Tooth Movement by Oral Administration of Pangasius hypophthalmus Oil: An in Vivo Study. Lubis, Hilda Fitria Idrus, Erik Sastradipura, Dewi Fatma Suniarti Suseno, Sugeng Heri Widayati, Retno Amir, Lisa Rinanda Bahtiar, Anton Jazaldi, Fadli Wulandari, Pitu Enhancing orthodontic tooth movement is a crucial aspect in reducing the duration of treatment. This study aims to investigate the potential of Pangasius hypophthalmus oil in promoting tooth movement in rabbits. Forty-eight male rabbits were employed in four experimental groups (n = 12 per group): Group 1 served as the control, while Groups 2, 3, and 4 received oral doses of Pangasius hypophthalmus oil at concentrations of 250 mg/kg body weight, 500 mg/kg body weight, and 1,000 mg/kg body weight, respectively. Orthodontic appliances were placed between the lower central incisors of the rabbits, applying an orthodontic force of 100 g/mm. The oil was administered orally to the rabbits every day for 14 days. Specimens were euthanised on day 1, 3, 7, or 14 according to the experimental group, and immunohistochemical analysis was conducted to evaluate TRAP and OPN expression in alveolar bone at compression sites. The administration of Pangasius hypophthalmus oil with a dose of 1,000 mg/kg body weight led to the highest increase of orthodontic movement, indicated by a rise of TRAP and OPN expression compared to other concentrations (p The Pangasius hypophthalmus oil has the potent ability to increase the orthodontic tooth movement, indicated by the rise in TRAP and OPN expression. |
| format | Artículo científico |
| id | pubmed_41964293 |
| institution | PubMed |
| language | en |
| publishDate | 2026 |
| publisher | Orthodontics & craniofacial research |
| record_format | pubmed |
| spellingShingle | Enhancement of Orthodontic Tooth Movement by Oral Administration of Pangasius hypophthalmus Oil: An in Vivo Study. Lubis, Hilda Fitria Idrus, Erik Sastradipura, Dewi Fatma Suniarti Suseno, Sugeng Heri Widayati, Retno Amir, Lisa Rinanda Bahtiar, Anton Jazaldi, Fadli Wulandari, Pitu Enhancement of Orthodontic Tooth Movement by Oral Administration of Pangasius hypophthalmus Oil: An in Vivo Study. Lubis, Hilda Fitria Idrus, Erik Sastradipura, Dewi Fatma Suniarti Suseno, Sugeng Heri Widayati, Retno Amir, Lisa Rinanda Bahtiar, Anton Jazaldi, Fadli Wulandari, Pitu Enhancing orthodontic tooth movement is a crucial aspect in reducing the duration of treatment. This study aims to investigate the potential of Pangasius hypophthalmus oil in promoting tooth movement in rabbits. Forty-eight male rabbits were employed in four experimental groups (n = 12 per group): Group 1 served as the control, while Groups 2, 3, and 4 received oral doses of Pangasius hypophthalmus oil at concentrations of 250 mg/kg body weight, 500 mg/kg body weight, and 1,000 mg/kg body weight, respectively. Orthodontic appliances were placed between the lower central incisors of the rabbits, applying an orthodontic force of 100 g/mm. The oil was administered orally to the rabbits every day for 14 days. Specimens were euthanised on day 1, 3, 7, or 14 according to the experimental group, and immunohistochemical analysis was conducted to evaluate TRAP and OPN expression in alveolar bone at compression sites. The administration of Pangasius hypophthalmus oil with a dose of 1,000 mg/kg body weight led to the highest increase of orthodontic movement, indicated by a rise of TRAP and OPN expression compared to other concentrations (p The Pangasius hypophthalmus oil has the potent ability to increase the orthodontic tooth movement, indicated by the rise in TRAP and OPN expression. |
| title | Enhancement of Orthodontic Tooth Movement by Oral Administration of Pangasius hypophthalmus Oil: An in Vivo Study. |
| url | https://pubmed.ncbi.nlm.nih.gov/41964293/ |