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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
The Journal of heredity
2026
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| Online Access: | https://pubmed.ncbi.nlm.nih.gov/41980082/ |
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| _version_ | 1868266061969752064 |
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| author | Hernandez, Keith M Martien, Karen K Baird, Robin W Schmitz, Matthew T Springer, Mark S Gatesy, John Mountcastle, Jacquelyn Tilley, Tatiana Abueg, Linelle Brajuka, Nadolina Balacco, Jennifer R Fedrigo, Olivier Formenti, Giulio Jarvis, Erich D Morin, Phillip A |
| author_facet | Hernandez, Keith M Martien, Karen K Baird, Robin W Schmitz, Matthew T Springer, Mark S Gatesy, John Mountcastle, Jacquelyn Tilley, Tatiana Abueg, Linelle Brajuka, Nadolina Balacco, Jennifer R Fedrigo, Olivier Formenti, Giulio Jarvis, Erich D Morin, Phillip A Hernandez, Keith M Martien, Karen K Baird, Robin W Schmitz, Matthew T Springer, Mark S Gatesy, John Mountcastle, Jacquelyn Tilley, Tatiana Abueg, Linelle Brajuka, Nadolina Balacco, Jennifer R Fedrigo, Olivier Formenti, Giulio Jarvis, Erich D Morin, Phillip A |
| collection | PubMed - marine biology |
| contents | Reference genome assembly of the false killer whale (Pseudorca crassidens). Hernandez, Keith M Martien, Karen K Baird, Robin W Schmitz, Matthew T Springer, Mark S Gatesy, John Mountcastle, Jacquelyn Tilley, Tatiana Abueg, Linelle Brajuka, Nadolina Balacco, Jennifer R Fedrigo, Olivier Formenti, Giulio Jarvis, Erich D Morin, Phillip A High-quality genomic resources are essential tools for conservation and management actions. We present a chromosome-level genome assembly for the false killer whale (Pseudorca crassidens, Owen, 1846), a large globicephaline delphinid found in tropical and subtropical waters. The final genome assembly is 2.7 Gb, with a scaffold N50 of 110.1 Mb, organized into 21 autosomes plus X and Y sex chromosomes. BUSCO scores were 97%, with low levels of duplicated and fragmented annotations. Repetitive elements were a larger proportion of the genome relative to most previously published cetacean genomes. Using this reference, we compared trends in historical demography and genome-wide heterozygosity in two North Pacific populations of false killer whales using short-read data mapped to the reference genome. Modeling of historical demography in these two populations indicate similar fluctuations in effective population size over time, reflecting shared ancestry until ~100-200 kya. Genome-wide heterozygosity levels were moderate relative to other cetaceans. The new genomic resources can facilitate further research on comparative genomics and can serve as a reference for other globicephaline cetaceans that currently lack chromosome-level genome assemblies. |
| format | Artículo científico |
| id | pubmed_41980082 |
| institution | PubMed |
| language | en |
| publishDate | 2026 |
| publisher | The Journal of heredity |
| record_format | pubmed |
| spellingShingle | Reference genome assembly of the false killer whale (Pseudorca crassidens). Hernandez, Keith M Martien, Karen K Baird, Robin W Schmitz, Matthew T Springer, Mark S Gatesy, John Mountcastle, Jacquelyn Tilley, Tatiana Abueg, Linelle Brajuka, Nadolina Balacco, Jennifer R Fedrigo, Olivier Formenti, Giulio Jarvis, Erich D Morin, Phillip A Reference genome assembly of the false killer whale (Pseudorca crassidens). Hernandez, Keith M Martien, Karen K Baird, Robin W Schmitz, Matthew T Springer, Mark S Gatesy, John Mountcastle, Jacquelyn Tilley, Tatiana Abueg, Linelle Brajuka, Nadolina Balacco, Jennifer R Fedrigo, Olivier Formenti, Giulio Jarvis, Erich D Morin, Phillip A High-quality genomic resources are essential tools for conservation and management actions. We present a chromosome-level genome assembly for the false killer whale (Pseudorca crassidens, Owen, 1846), a large globicephaline delphinid found in tropical and subtropical waters. The final genome assembly is 2.7 Gb, with a scaffold N50 of 110.1 Mb, organized into 21 autosomes plus X and Y sex chromosomes. BUSCO scores were 97%, with low levels of duplicated and fragmented annotations. Repetitive elements were a larger proportion of the genome relative to most previously published cetacean genomes. Using this reference, we compared trends in historical demography and genome-wide heterozygosity in two North Pacific populations of false killer whales using short-read data mapped to the reference genome. Modeling of historical demography in these two populations indicate similar fluctuations in effective population size over time, reflecting shared ancestry until ~100-200 kya. Genome-wide heterozygosity levels were moderate relative to other cetaceans. The new genomic resources can facilitate further research on comparative genomics and can serve as a reference for other globicephaline cetaceans that currently lack chromosome-level genome assemblies. |
| title | Reference genome assembly of the false killer whale (Pseudorca crassidens). |
| url | https://pubmed.ncbi.nlm.nih.gov/41980082/ |