Marine-derived products as pharmaceutical treasure troves: a focus on recent research techniques and potential bioactive activities of marine peptides.

Fuente: PubMed
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Autori principali: Cheng, Xiangyu, Tang, Ziqi, Li, Zhongqi, Hu, Shuaijie, Qin, Kehan, Zhao, Yindi, Hao, Baoming, Hu, Qinghua
Natura: Artículo científico
Lingua:en
Pubblicazione: Chinese journal of natural medicines 2026
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author Cheng, Xiangyu
Tang, Ziqi
Li, Zhongqi
Hu, Shuaijie
Qin, Kehan
Zhao, Yindi
Hao, Baoming
Hu, Qinghua
author_facet Cheng, Xiangyu
Tang, Ziqi
Li, Zhongqi
Hu, Shuaijie
Qin, Kehan
Zhao, Yindi
Hao, Baoming
Hu, Qinghua
Cheng, Xiangyu
Tang, Ziqi
Li, Zhongqi
Hu, Shuaijie
Qin, Kehan
Zhao, Yindi
Hao, Baoming
Hu, Qinghua
collection PubMed - marine biology
contents Marine-derived products as pharmaceutical treasure troves: a focus on recent research techniques and potential bioactive activities of marine peptides. Cheng, Xiangyu Tang, Ziqi Li, Zhongqi Hu, Shuaijie Qin, Kehan Zhao, Yindi Hao, Baoming Hu, Qinghua Peptides Aquatic Organisms Animals Humans Biological Products Computational Biology With the intensified exploration of marine resources, marine bioactive peptides have become one of the research focuses in biomedicine, food science, and materials science because of their structural diversity, unique biological activities, and broad application potential. At present, the extraction of marine peptides has expanded beyond conventional chemical extraction and enzymatic hydrolysis, with microbial fermentation and gastrointestinal simulation technologies further broadening peptide diversity. In addition, the integration of multiple chromatographic techniques with advanced detectors has significantly improved the efficiency of marine peptide identification. Owing to their diverse biological activities, including immunoregulatory, antioxidant, antibacterial, antitumor, hypotensive, and hypoglycemic effects, marine peptides not only enrich the pool of candidates for marine drug development but also provide new perspectives for addressing numerous health challenges. Importantly, substantial progress has been made in the screening, identification, and mechanistic elucidation of marine bioactive peptides, driven by advances in high-throughput technologies and the bioinformatics. However, marine peptide research still faces several challenges, including complex sourcing, difficulties in large-scale acquisition, and insufficient exploration of biological activities. Therefore, this article concisely reviews recent progress in the extraction, purification, and identification of marine bioactive peptides, summarizes current research on their biological activities, and highlights the application of bioinformatics in marine peptide studies.
format Artículo científico
id pubmed_42062029
institution PubMed
language en
publishDate 2026
publisher Chinese journal of natural medicines
record_format pubmed
spellingShingle Marine-derived products as pharmaceutical treasure troves: a focus on recent research techniques and potential bioactive activities of marine peptides.
Cheng, Xiangyu
Tang, Ziqi
Li, Zhongqi
Hu, Shuaijie
Qin, Kehan
Zhao, Yindi
Hao, Baoming
Hu, Qinghua
Peptides
Aquatic Organisms
Animals
Humans
Biological Products
Computational Biology
Marine-derived products as pharmaceutical treasure troves: a focus on recent research techniques and potential bioactive activities of marine peptides. Cheng, Xiangyu Tang, Ziqi Li, Zhongqi Hu, Shuaijie Qin, Kehan Zhao, Yindi Hao, Baoming Hu, Qinghua Peptides Aquatic Organisms Animals Humans Biological Products Computational Biology With the intensified exploration of marine resources, marine bioactive peptides have become one of the research focuses in biomedicine, food science, and materials science because of their structural diversity, unique biological activities, and broad application potential. At present, the extraction of marine peptides has expanded beyond conventional chemical extraction and enzymatic hydrolysis, with microbial fermentation and gastrointestinal simulation technologies further broadening peptide diversity. In addition, the integration of multiple chromatographic techniques with advanced detectors has significantly improved the efficiency of marine peptide identification. Owing to their diverse biological activities, including immunoregulatory, antioxidant, antibacterial, antitumor, hypotensive, and hypoglycemic effects, marine peptides not only enrich the pool of candidates for marine drug development but also provide new perspectives for addressing numerous health challenges. Importantly, substantial progress has been made in the screening, identification, and mechanistic elucidation of marine bioactive peptides, driven by advances in high-throughput technologies and the bioinformatics. However, marine peptide research still faces several challenges, including complex sourcing, difficulties in large-scale acquisition, and insufficient exploration of biological activities. Therefore, this article concisely reviews recent progress in the extraction, purification, and identification of marine bioactive peptides, summarizes current research on their biological activities, and highlights the application of bioinformatics in marine peptide studies.
title Marine-derived products as pharmaceutical treasure troves: a focus on recent research techniques and potential bioactive activities of marine peptides.
topic Peptides
Aquatic Organisms
Animals
Humans
Biological Products
Computational Biology
url https://pubmed.ncbi.nlm.nih.gov/42062029/