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| Main Authors: | , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Journal of structural biology
2026
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/42081960/ |
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Table of Contents:
- In situ loading and patterns of trabecular deformation in the intermediale of the vertebral centrum of a great hammerhead. Parker, J T Comes, J S Passerotti, M S Natanson, L J Seto, J Parkinson, D Y Stock, S R Animals Sharks X-Ray Microtomography Spine Cancellous Bone Cartilage Biomechanical Phenomena Synchrotrons The vertebral centra of sharks consist of cartilage, and many species' centra are mineralized. The main centrum structures, the corpus calcareum and intermedialia, consist of an interconnected network of thin, closely-spaced, mineralized trabeculae and of unmineralized volumes which are also interconnected. In vivo, the centra survive millions of cycles of large amplitude compressions, and we hypothesized that reversible trabecular deflections/rotations make this possible. The hypothesis was directly tested using in situ compression of three small blocks cut from a great hammerhead intermediale and synchrotron microComputed Tomography. The BoneJ plugin for ImageJ was used to quantify trabecular spacings and trabecular thicknesses at multiple subvolumes within each block. Changes in applied strain of 4% produced little change in trabecular thickness and appreciable changes in trabecular spacing, confirming the hypothesis that the large applied strain was accommodated by deflections/rotations of trabeculae.