Image de couverture de livre

The New Delhi Metallo-β-lactamase-1 Covalent Inhibitors Derived from Cephalexin Effectively Reverse Meropenem Resistance.

Fuente: PubMed

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Liu, Wandong, Liu, Chenyu, Guo, Yan, Liu, Zhiying, Zhang, Chen, Meng, Wanli, Wan, Shengbiao, Chen, Sheng, Qiu, Jiazhang, Yu, Rilei
Format:	Artículo científico
Langue:	en
Publié:	Journal of medicinal chemistry 2026
Sujets:	beta-Lactamase Inhibitors Meropenem beta-Lactamases Animals Anti-Bacterial Agents Mice Microbial Sensitivity Tests Cephalexin Structure-Activity Relationship
Accès en ligne:	Acceder al recurso
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Structure-Directed Optimization of Ebselen Derivatives as Potent NDM-1 Inhibitors Reverses Meropenem Resistance.
par: Guo, Yan, et autres
Publié: (2025)

Development of molecular Trojan horses targeting New Delhi metallo-β-lactamase-1 for the restoration of meropenem susceptibility in drug-resistant bacteria.
par: Liu, Wandong, et autres
Publié: (2025)

Computer-aided screening of marine fungal metabolites as potential inhibitors of new Delhi metallo-beta-lactamase-1.
par: Shabbir, Farhat, et autres
Publié: (2025)

The impact of aztreonam-clavulanic acid exposure on gene expression and mutant selection using a multidrug-resistant .
par: Lin, Tongtong, et autres
Publié: (2025)

Integrons are key players in the spread of beta-lactamase-encoding genes.
par: Tavares, Rafael D S, et autres
Publié: (2025)

Genomic characterization of colistin- and carbapenem-resistant Pseudomonas aeruginosa ST1560 from Guanabara Bay, Brazil.
par: Assunção, Vinicius Carneiro, et autres
Publié: (2026)

Deciphering structuring mechanism and increased health risk of antibiotic resistome from a coastal river basin to the downstream estuary and bay under anthropogenic disturbances.
par: Huang, Xinyu, et autres
Publié: (2025)

Combination of antimicrobial peptide and clinical antibiotic shows enhanced potency toward Acinetobacter baumannii infection.
par: Yeh, Jih-Chao, et autres
Publié: (2025)

Descrição e caracterização molecular de metalo-betalactamase SPM-1 em linhagens clínicas de Pseudomonas aeruginosa em Goiânia, Brasil.
par: Rodrigo Alves de Oliveira
Publié: (2014)

Mudskipper β-def2 exhibits potent broad-spectrum bactericidal activity via membrane-disrupting and DNA-targeting mechanisms.
par: Hu, Ya-Zhen, et autres
Publié: (2025)

New Fusarochromanone Derivatives from the Marine Fungus UBOCC-A-117302.
par: Pham, Giang Nam, et autres
Publié: (2024)

Multi-target anti-MRSA mechanism and antibiotic synergistic effect of marine alkaloid Ascomylactam A in vitro and in vivo against clinical MRSA strains.
par: Wu, Ke-Yue, et autres
Publié: (2025)

Isoniazid potentiates tigecycline to kill methicillin-resistant .
par: Chen, Xuan-Wei, et autres
Publié: (2025)

DL-propargylglycine reverses beta-lactam resistance in Streptococcus agalactiae.
par: Chen, Xuan-Wei, et autres
Publié: (2026)

Self-assembly antimicrobial peptide for treatment of multidrug-resistant bacterial infection.
par: Ma, Xuanxuan, et autres
Publié: (2024)

A Self-Assembling Peptide with Nanoparticle-to-Fibril Transformation Exhibits Multimodal Antimicrobial Activity through Membrane Disruption and Quorum-Sensing Inhibition.
par: Mwangi, James, et autres
Publié: (2025)

Compound amino acid synergizes ceftazidime-avibactam to eradicate extracellular and facultative intracellular MDR pathogens.
par: Xiang, Jiao, et autres
Publié: (2026)

Glutamine Potentiates Cefoperazone-Sulbactam against by Enhancing Cellular Uptake and ROS Production.
par: Li, Shao-Hua, et autres
Publié: (2026)

Glutamine Potentiates Cefoperazone-Sulbactam Activity against by Increasing Drug Uptake and ROS.
par: Wang, Shi-Wen, et autres
Publié: (2025)

Antimicrobial, Antioxidant and Anti-Inflammatory Activities of the Mucus of the Tropical Sea Slug .
par: Lopes, Diana, et autres
Publié: (2024)

Antimicrobial resistance and biofilm production by Staphylococcus spp. and Mammaliicoccus Sciuri in Inia araguaiaensis: surveillance under a one health perspective in the Amazon.
par: Leite, Denny Parente de Sá Barreto Maia, et autres
Publié: (2025)

Occurrence of antibiotic-resistant bacteria in the sea surface microlayer of coastal waters in the southern North Sea.
par: Adenaya, Adenike, et autres
Publié: (2024)

Genome-Driven Discovery of Neuraminidase-Inhibiting and Antibacterial Chermsinols A and B: Orsellinic-Acid-Derived Steroid and Meroterpenoid from Marine-Sourced .
par: Hu, Xue-Yi, et autres
Publié: (2026)

Preparation and antibacterial properties of benzisothiazolinone quaternized chitosan derivatives for sustainable fuel preservation.
par: Liu, Lijia, et autres
Publié: (2025)

Antibacterial potential of epiphytic fungi obtained from brown algae of Kenyan coastal waters.
par: Sendekie, Aragaw Zemene, et autres
Publié: (2026)

Discovery of Antimicrobial Oligoindoles from a Cold-Seep-Derived Strain.
par: Yan, Yunchen, et autres
Publié: (2025)

Disulfide-bonded YC18: A membrane-targeting peptide with superior efficacy against Staphylococcus aureus infections.
par: Gao, Jinai, et autres
Publié: (2026)

Highly oxygenated acorane sesquiterpenes from the marine-sourced Trichoderma harzianum CS-152.
par: Li, Yan-He, et autres
Publié: (2025)

Mucoadhesive lignin-liposome nanocarriers of coptisine: A multifunctional strategy against antibiotic-resistant Helicobacter pylori biofilms.
par: Sharaf, Mohamed, et autres
Publié: (2026)

Extraction and characterization of antibacterial marine polysaccharide K-Carrageenan from Kappaphycus alvarezii against multidrug-resistant wound associated bacteria.
par: Ramachandran, Ishwarya, et autres
Publié: (2025)

Discovery of antimicrobial activity in chemical extracts derived from unexplored algal-bacterial culture systems and isolates.
par: Fisher, Carolyn L, et autres
Publié: (2024)

Chermesins I-N: Bioactive spiromeroterpenoids from the marine-sourced fungus Penicillium chermesinum AS-400.
par: Liu, Yi-Wei, et autres
Publié: (2025)

A Potent Antibacterial Peptide (P6) from the De Novo Transcriptome of the Microalga .
par: Zhang, Kexin, et autres
Publié: (2024)

Genomic description of sp. nov., a bacterium collected from the International Space Station that exhibits unique antimicrobial-resistant and virulent phenotype.
par: Hill, Megan S, et autres
Publié: (2025)

Ultrafast Evolution of Bacterial Antimicrobial Resistance by Picoliter-Scale Centrifugal Microfluidics.
par: Xu, Teng, et autres
Publié: (2024)

Marine-Inspired Antimicrobial Peptides Disrupt Gene Expression at the DNA Level.
par: Beyer, Luisa I, et autres
Publié: (2026)

Identification of a novel antimicrobial peptide Gp-AMP1 with broad-spectrum and exceptional stability from deep-sea mussel Gigantidas platifrons.
par: Han, Guanghui, et autres
Publié: (2026)

Lighting Up Healing: Green Light-Driven Dual Gasotransmitters Release against MRSA Wound Infections.
par: Hou, Yanyan, et autres
Publié: (2025)

Impact of Limosilactobacillus reuteri cell-free culture supernatant on stress-resistant Salmonella Typhimurium in seawater: antioxidant, anti-infective, and anti-adhesion effects.
par: Chakroun, Ibtissem, et autres
Publié: (2025)

Zopfiellamides C and D, New Decalin-Type Tetramic Acid Derivatives from the Marine-Derived Fungus sp. NF666.
par: Jiao, Fangwen, et autres
Publié: (2025)