Buchumschlag

Data-Independent Acquisition-Based Quantitative Proteomics, Nontargeted Metabolomics, and Protein-Ligand Interaction Reveal the Mechanism of Baicalin Inhibiting βhemolytic/cytolytic Activities of .

Fuente: PubMed

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Li, Guihua, Liu, Shaolong, Zhao, Zichen, Shuli, Jundi, Xiang, Mingli, Wang, Yan, Sun, Yun, Zhong, Zhihong, Wang, Shifeng, Zhang, Chen, Guo, Weiliang, Zhou, Yongcan
Format:	Artículo científico
Sprache:	en
Veröffentlicht:	Journal of agricultural and food chemistry 2026
Schlagworte:	Flavonoids Proteomics Streptococcus agalactiae Bacterial Proteins Molecular Docking Simulation Metabolomics Ligands Anti-Bacterial Agents Phosphorylation Protein Serine-Threonine Kinases
Online-Zugang:	Acceder al recurso
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge

Identification of novel CLK1 inhibitors by computational fragment-based ligand design, co-crystallization, chemical synthesis and structure activity relationships.
von: Bourg, Stéphane, et al.
Veröffentlicht: (2026)

Transcriptome analysis of tilapia streptococcus agalactiae in response to baicalin.
von: Huang, Qing-Qin, et al.
Veröffentlicht: (2025)

Comparative proteomics of biofilm development in discovers a distinct family of Ca-dependent adhesins.
von: Ali, Sura, et al.
Veröffentlicht: (2025)

Phosphorylation of peptides by a kinase domain in cyanobactin pathways.
von: Castelo-Branco, Raquel, et al.
Veröffentlicht: (2025)

Identification of Marine Compounds Inhibiting NF-κBInducing Kinase Through Molecular Docking and Molecular Dynamics Simulations.
von: Yasir, Muhammad, et al.
Veröffentlicht: (2024)

Elucidation of anti-human melanoma and anti-aging mechanisms of compounds from green seaweed Caulerpa racemosa.
von: Wicaksono, Danar, et al.
Veröffentlicht: (2024)

Phosphoethanolamine cytidylyltransferase 2 integrates DAG metabolism and TBK1 activation to regulate antiviral innate immunity.
von: Lai, Wencong, et al.
Veröffentlicht: (2026)

Epicoccin A Ameliorates PD-like Symptoms in Zebrafish: Enhancement of PINK1/Parkin-Dependent Mitophagy and Inhibition of Excessive Oxidative Stress.
von: Ye, Haicheng, et al.
Veröffentlicht: (2025)

Regulation of the non-selective Na importer capacity of NRT1.2/NPF4.6/AIT1 by SOS2-mediated phosphorylation in Arabidopsis.
von: Liu, Xiaoxiao, et al.
Veröffentlicht: (2025)

Metabolomics-Guided Discovery of Bipolarolides H-O, New Ophiobolin-Type Sesterterpenes with Antibacterial Activity from the Marine-Derived Fungus sp. nov.
von: Maharjan, Sailesh, et al.
Veröffentlicht: (2025)

SVCV phosphoprotein hijacks phase separation to immobilize the IRF3-TBK1 signaling axis and suppress interferon antiviral immunity.
von: Wang, Yueyi, et al.
Veröffentlicht: (2026)

Evolutionary analysis and immune-induced expression and mA modification of RIPK1 and RIPK2 in the miiuy croaker.
von: Xing, Qianru, et al.
Veröffentlicht: (2025)

Computational insights into marine natural products as potential antidiabetic agents targeting the SIK2 protein kinase domain.
von: Heyram, K, et al.
Veröffentlicht: (2024)

Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response.
von: Lu, Long-Feng, et al.
Veröffentlicht: (2026)

Pan-cancer analysis of CDC7 in human tumors: Integrative multi-omics insights and discovery of novel marine-based inhibitors through machine learning and computational approaches.
von: Saif, Ahmed, et al.
Veröffentlicht: (2025)

Eeukaryotic-like Sppsk1 from Vibrio splendidus AJ01 mediates phagosome escape via inhibiting phagosome acidification and maturation.
von: Dai, Fa, et al.
Veröffentlicht: (2025)

BIK1 and ATL31/6 are essential for fucoidan hydrolysate-triggered stomatal closure in Arabidopsis.
von: Chen, Kexin, et al.
Veröffentlicht: (2025)

Primary Cilia-Mediated Hedgehog Signaling Regulates Cell Fate During ER Stress-Induced Life or Death Decisions.
von: Xu, Jia, et al.
Veröffentlicht: (2025)

Cryo-EM structure of the QseG-QseE complex reveals an accessory protein-driven two-component system activation mechanism.
von: Gong, Piqian, et al.
Veröffentlicht: (2025)

protein kinase MAK phosphorylates FAP256/CEP104 and regulates axonemal microtubule assembly.
von: Zhang, Yi, et al.
Veröffentlicht: (2025)

Computational Analysis of Azole Derivatives Targeting the PI3K/AKT/mTOR Pathway With In Vitro Cytotoxicity and Autophagy Evaluation.
von: Regurajan, Rathika, et al.
Veröffentlicht: (2026)

Genome-guided isolation of the hyperthermophilic aerobe Fervidibacter sacchari reveals conserved polysaccharide metabolism in the Armatimonadota.
von: Nou, Nancy O, et al.
Veröffentlicht: (2024)

Fructan utilization by members of marine Gammaproteobacteria involves SusC/D-like proteins.
von: Zühlke, Marie-Katherin, et al.
Veröffentlicht: (2026)

Grass carp reovirus VP6 inhibits IFN production by degrading TBK1 through the autophagy pathway.
von: Xu, Xiao, et al.
Veröffentlicht: (2025)

Analysis of variations in cell envelope subproteome and cell length in Acinetobacter baumannii ATCC 19606 populations by effect of temperature and desiccation.
von: Orruño, Maite, et al.
Veröffentlicht: (2025)

Multifunctionally diverse alkaline phosphatases of Alteromonas drive the phosphorus cycle in the ocean.
von: Saavedra, Daniel E M, et al.
Veröffentlicht: (2025)

Synthesis and biological activity of 1H-pyrrolo[3,2-g]isoquinolines as Haspin kinase inhibitors.
von: Malosse, Killian, et al.
Veröffentlicht: (2025)

Post-translational modifications of GlmR integrate metabolic and stress signals to maintain cell envelope homeostasis in Bacillus subtilis.
von: Suits, Logan B, et al.
Veröffentlicht: (2026)

Decoding the catalytic potential of a Cycloclasticus zancles ring-hydroxylating dioxygenase through computational analysis for enhanced PAH biodegradation.
von: Naveed, Muhammad, et al.
Veröffentlicht: (2026)

KiNext: a portable and scalable workflow for the identification and classification of protein kinases.
von: Hellec, Elisabeth, et al.
Veröffentlicht: (2024)

Transitions in the proteome and phospho-proteome during Xenopus laevis development.
von: Van Itallie, Elizabeth, et al.
Veröffentlicht: (2025)

PI3K-AKT-mediated phosphorylation of Thr260 in CgCaspase-3/6/7 regulates heat-induced activation in oysters.
von: Wang, Chaogang, et al.
Veröffentlicht: (2024)

Exploring Marine natural products as potential Quorum sensing inhibitors by targeting the PqsR in Pseudomonas aeruginosa: Virtual screening assisted structural dynamics study.
von: Jayaraman, Manikandan, et al.
Veröffentlicht: (2025)

Competition and interdependence define interactions of Nostoc sp. and Agrobacterium sp. under inorganic carbon limitation.
von: Teikari, Jonna E, et al.
Veröffentlicht: (2025)

Chemical Evolution of Aplithianine Class of Serine/Threonine Kinase Inhibitors.
von: Du, Lin, et al.
Veröffentlicht: (2025)

Activation of prep expression by Tet2 promotes the proliferation of bipotential progenitor cells during liver regeneration.
von: Jia, Kun, et al.
Veröffentlicht: (2025)

Crystal structure and catalytic mechanism of PL35 family glycosaminoglycan lyases with an ultrabroad substrate spectrum.
von: Wei, Lin, et al.
Veröffentlicht: (2025)

A nutrient-responsive AMPK/TBK1 circuit restricts adipocyte catabolism.
von: Wisessaowapak, Churaibhon, et al.
Veröffentlicht: (2026)

DHA affects ISKNV-induced autophagy flux via the AMPK/mTOR/ULK1 and BECN1/SQSTM1 axes, limiting viral replication in fish cells.
von: Chen, Kuang-Wen, et al.
Veröffentlicht: (2026)

Identification of Compounds Inhibiting Thermolabile Hemolysin from in Shrimp.
von: Bari, Sayed Mashequl, et al.
Veröffentlicht: (2025)