Male reproduction and environmental and occupational exposures: a review of epidemiologic methods
Fuente:
Redalyc
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Artículo científico |
| Sprache: | en |
| Veröffentlicht: |
Instituto Nacional de Salud Pública
1999
|
| Schlagworte: | |
| Online-Zugang: | |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| _version_ | 1876486010008764416 |
|---|---|
| author | Jacqueline M. Moline |
| author_facet | Jacqueline M. Moline |
| contents | Male reproduction and environmental and occupational exposures: a review of epidemiologic methods Jacqueline M. Moline Anne L. Golden Natan Bar Salud male fertility reproduction occupational exposure environmental exposure Concerns that chemical exposures in the environment havebeen detrimental to male sexual development and fertilityhave been heightened by reports of declining sperm countsover the past 50 years. Marked geographic variation hasbeen found in semen quality and in the incidence of testicularcancer and certain urogenital defects. Debate continuesover the existence, magnitude and significance of thesetrends, and how best to evaluate the hypothesis that in uteroand childhood exposures to estrogenic compounds maybe to blame. Epidemiologic methods for assessing the impactof hazardous substances on male reproductive healthhave been developed mainly in the area of occupational medicine,and this paper will review the currently recommendedmethods. These include questionnaires to determine reproductivehistory and sexual function; reproductive hormoneprofiles; and semen analyses such as sperm concentration,motility, and morphology. New research tools that showsignificant promise from the fields of clinical reproductivemedicine and reproductive toxicology are discussed as possibleadditions to epidemiologic studies, including assays ofsperm function and genetic integrity, and biomarkers of DNAdamage. For population-based studies involving occupationalgroups or communities with environmental exposures, issuesrelated to the cost, validity, precision and utility of thesemethods must be carefully considered. 1999 artículo científico 0036-3634 https://www.redalyc.org/articulo.oa?id=10609405 en http://www.redalyc.org/revista.oa?id=106 Salud Pública de México application/pdf Instituto Nacional de Salud Pública Salud Pública de México (México) Num.2 Vol.41 |
| format | Artículo científico |
| id | redalyc_10609405 |
| institution | Redalyc |
| language | en |
| publishDate | 1999 |
| publisher | Instituto Nacional de Salud Pública |
| spellingShingle | Male reproduction and environmental and occupational exposures: a review of epidemiologic methods Jacqueline M. Moline Salud male fertility reproduction occupational exposure environmental exposure Male reproduction and environmental and occupational exposures: a review of epidemiologic methods Jacqueline M. Moline Anne L. Golden Natan Bar Salud male fertility reproduction occupational exposure environmental exposure Concerns that chemical exposures in the environment havebeen detrimental to male sexual development and fertilityhave been heightened by reports of declining sperm countsover the past 50 years. Marked geographic variation hasbeen found in semen quality and in the incidence of testicularcancer and certain urogenital defects. Debate continuesover the existence, magnitude and significance of thesetrends, and how best to evaluate the hypothesis that in uteroand childhood exposures to estrogenic compounds maybe to blame. Epidemiologic methods for assessing the impactof hazardous substances on male reproductive healthhave been developed mainly in the area of occupational medicine,and this paper will review the currently recommendedmethods. These include questionnaires to determine reproductivehistory and sexual function; reproductive hormoneprofiles; and semen analyses such as sperm concentration,motility, and morphology. New research tools that showsignificant promise from the fields of clinical reproductivemedicine and reproductive toxicology are discussed as possibleadditions to epidemiologic studies, including assays ofsperm function and genetic integrity, and biomarkers of DNAdamage. For population-based studies involving occupationalgroups or communities with environmental exposures, issuesrelated to the cost, validity, precision and utility of thesemethods must be carefully considered. 1999 artículo científico 0036-3634 https://www.redalyc.org/articulo.oa?id=10609405 en http://www.redalyc.org/revista.oa?id=106 Salud Pública de México application/pdf Instituto Nacional de Salud Pública Salud Pública de México (México) Num.2 Vol.41 |
| title | Male reproduction and environmental and occupational exposures: a review of epidemiologic methods |
| topic | Salud male fertility reproduction occupational exposure environmental exposure |
| url | https://www.redalyc.org/articulo.oa?id=10609405 |