Risk factors associated to diabetes in Mexican population and phenotype of the individuals who will convert to diabetes

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1. Verfasser: Clicerio González-Villalpando
Format: Artículo científico
Sprache:en
Veröffentlicht: Instituto Nacional de Salud Pública 2014
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author Clicerio González-Villalpando
author_facet Clicerio González-Villalpando
contents Risk factors associated to diabetes in Mexican population and phenotype of the individuals who will convert to diabetes Clicerio González-Villalpando Claudio Alberto Dávila-Cervantes Mireya Zamora-Macorra Belem Trejo-Valdivia María Elena González-Villalpando Salud Mexico incidence phenotype risk factors Diabetes mellitus Objective. To describe risk factors associated to the incidence of type 2 diabetes (T2D) in Mexican population and to define phenotypic (clinical, anthropometric, metabolic) characteristics present in the individual who will convert to diabetes, regardless of time of onset. Materials and methods. The Mexico City Diabetes Study began in 1990, with 2 282 participants, and had three subsequent phases: 1994, 1998, and 2008. A systematic evaluation with an oral glucose tolerance test was performed in each phase. For diagnosis of T2D, American Diabetes Association criteria were used. Results. The population at risk was 1939 individuals. Subjects who were in the converter stage (initially non diabetic that eventually converted to T2D) had, at baseline, higher BMI (30 vs 27), systolic blood pressure (119 vs 116 mmHg), fasting glucose (90 vs 82mg/dl), triglycerides (239 vs 196mg/dl), and cholesterol (192 vs 190mg/dl), compared with subjects who remained non converters (p<0.05). Conclusion. The phenotype described represents a potentially identifiable phase and a target for preventive intervention. 2014 artículo científico 0036-3634 https://www.redalyc.org/articulo.oa?id=10632372002 en http://www.redalyc.org/revista.oa?id=106 Salud Pública de México application/pdf Instituto Nacional de Salud Pública Salud Pública de México (México) Num.4 Vol.56
format Artículo científico
id redalyc_10632372002
institution Redalyc
language en
publishDate 2014
publisher Instituto Nacional de Salud Pública
spellingShingle Risk factors associated to diabetes in Mexican population and phenotype of the individuals who will convert to diabetes
Clicerio González-Villalpando
Salud
Mexico
incidence
phenotype
risk factors
Diabetes mellitus
Risk factors associated to diabetes in Mexican population and phenotype of the individuals who will convert to diabetes Clicerio González-Villalpando Claudio Alberto Dávila-Cervantes Mireya Zamora-Macorra Belem Trejo-Valdivia María Elena González-Villalpando Salud Mexico incidence phenotype risk factors Diabetes mellitus Objective. To describe risk factors associated to the incidence of type 2 diabetes (T2D) in Mexican population and to define phenotypic (clinical, anthropometric, metabolic) characteristics present in the individual who will convert to diabetes, regardless of time of onset. Materials and methods. The Mexico City Diabetes Study began in 1990, with 2 282 participants, and had three subsequent phases: 1994, 1998, and 2008. A systematic evaluation with an oral glucose tolerance test was performed in each phase. For diagnosis of T2D, American Diabetes Association criteria were used. Results. The population at risk was 1939 individuals. Subjects who were in the converter stage (initially non diabetic that eventually converted to T2D) had, at baseline, higher BMI (30 vs 27), systolic blood pressure (119 vs 116 mmHg), fasting glucose (90 vs 82mg/dl), triglycerides (239 vs 196mg/dl), and cholesterol (192 vs 190mg/dl), compared with subjects who remained non converters (p<0.05). Conclusion. The phenotype described represents a potentially identifiable phase and a target for preventive intervention. 2014 artículo científico 0036-3634 https://www.redalyc.org/articulo.oa?id=10632372002 en http://www.redalyc.org/revista.oa?id=106 Salud Pública de México application/pdf Instituto Nacional de Salud Pública Salud Pública de México (México) Num.4 Vol.56
title Risk factors associated to diabetes in Mexican population and phenotype of the individuals who will convert to diabetes
topic Salud
Mexico
incidence
phenotype
risk factors
Diabetes mellitus
url https://www.redalyc.org/articulo.oa?id=10632372002