Evaluación del 1-hidroxipireno como bioindicador de la exposición industrial a los hidrocarburos aromáticos policíclicos

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Main Author: Francisco Mercado
Format: Artículo científico
Language:en
Published: Instituto Nacional de Salud Pública 1993
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author Francisco Mercado
author_facet Francisco Mercado
contents Evaluación del 1-hidroxipireno como bioindicador de la exposición industrial a los hidrocarburos aromáticos policíclicos Francisco Mercado Salud hydroxypyrene bioindicators biological monitoring coke production plant polycyclic aromatic hydrocarbons One hundred and twenty two workers (16 from a coke production plant, 106 from a graphite electrode manufacturing plant) agreed to participate in this study designed to evaluate the relationship between the exposure to polycyclic aromatic hydrocarbons (PAHS) and the urinary excretion of 1- hydroxypyrene (1-HOP), the main metabolite of pyrene. The results show that the concentration of pyrene in air is highly correlated with total PAHS amount (r= 0.083, p<0.001), with a the correlation coefficient between 1-HOP and total PAS of r= 0.72 (p<0.001). The biological half life of the 1- HOP was determined (18 hrs) and the non interference of smoking habits in relation to 1-HOP urinary was established, concluding that 1-HOP is a suitable bioindicator of the occupational exposure to PAHS 1993 otro 0036-3634 https://www.redalyc.org/articulo.oa?id=10635612 en http://www.redalyc.org/revista.oa?id=106 Salud Pública de México application/pdf Instituto Nacional de Salud Pública Salud Pública de México (México) Num.6 Vol.35
format Artículo científico
id redalyc_10635612
institution Redalyc
language en
publishDate 1993
publisher Instituto Nacional de Salud Pública
spellingShingle Evaluación del 1-hidroxipireno como bioindicador de la exposición industrial a los hidrocarburos aromáticos policíclicos
Francisco Mercado
Salud
hydroxypyrene
bioindicators
biological monitoring
coke production plant
polycyclic aromatic hydrocarbons
Evaluación del 1-hidroxipireno como bioindicador de la exposición industrial a los hidrocarburos aromáticos policíclicos Francisco Mercado Salud hydroxypyrene bioindicators biological monitoring coke production plant polycyclic aromatic hydrocarbons One hundred and twenty two workers (16 from a coke production plant, 106 from a graphite electrode manufacturing plant) agreed to participate in this study designed to evaluate the relationship between the exposure to polycyclic aromatic hydrocarbons (PAHS) and the urinary excretion of 1- hydroxypyrene (1-HOP), the main metabolite of pyrene. The results show that the concentration of pyrene in air is highly correlated with total PAHS amount (r= 0.083, p<0.001), with a the correlation coefficient between 1-HOP and total PAS of r= 0.72 (p<0.001). The biological half life of the 1- HOP was determined (18 hrs) and the non interference of smoking habits in relation to 1-HOP urinary was established, concluding that 1-HOP is a suitable bioindicator of the occupational exposure to PAHS 1993 otro 0036-3634 https://www.redalyc.org/articulo.oa?id=10635612 en http://www.redalyc.org/revista.oa?id=106 Salud Pública de México application/pdf Instituto Nacional de Salud Pública Salud Pública de México (México) Num.6 Vol.35
title Evaluación del 1-hidroxipireno como bioindicador de la exposición industrial a los hidrocarburos aromáticos policíclicos
topic Salud
hydroxypyrene
bioindicators
biological monitoring
coke production plant
polycyclic aromatic hydrocarbons
url https://www.redalyc.org/articulo.oa?id=10635612