Primary drug resistance in a region with high burden of tuberculosis. A critical problem
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| Natura: | Artículo científico |
| Lingua: | en |
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Instituto Nacional de Salud Pública
2015
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| _version_ | 1876451056995532800 |
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| author | Cecilia Villa-Rosas |
| author_facet | Cecilia Villa-Rosas |
| contents | Primary drug resistance in a region with high burden of tuberculosis. A critical problem Cecilia Villa-Rosas Rafael Laniado-Laborín Lorena Oceguera-Palao Salud Rosas isoniazid rifampin Villa Treatment outcome resistance amplification Objective. To determine rates of drug resistance in new cases of pulmonary tuberculosis in a region with a high burden of the disease. Materials and methods. New case suspects were referred for drug susceptibility testing. Results. 28.9% of new cases were resistant to at least one first line drug; 3.9% had a multidrug-resistant strain, 15.6% a monoresistant strain and 9.4% a polyresistant strain. Conclusion. Our rate of drug resistant tuberculosis in new cases is very high; this has important clinical implications, since even monoresistance can have a negative impact on the outcome of new cases treated empirically with a six month regimen. C, Laniado-Laborín R, Oceguera-Palao L. Farmacorresistencia en casos nuevos en una región con alta carga de tuberculosis. Un problema crítico. Salud Publica Mex 2015;57:177-179. 2015 artículo científico 0036-3634 https://www.redalyc.org/articulo.oa?id=10636867009 en http://www.redalyc.org/revista.oa?id=106 Salud Pública de México application/pdf Instituto Nacional de Salud Pública Salud Pública de México (México) Num.2 Vol.57 |
| format | Artículo científico |
| id | redalyc_10636867009 |
| institution | Redalyc |
| language | en |
| publishDate | 2015 |
| publisher | Instituto Nacional de Salud Pública |
| spellingShingle | Primary drug resistance in a region with high burden of tuberculosis. A critical problem Cecilia Villa-Rosas Salud Rosas isoniazid rifampin Villa Treatment outcome resistance amplification Primary drug resistance in a region with high burden of tuberculosis. A critical problem Cecilia Villa-Rosas Rafael Laniado-Laborín Lorena Oceguera-Palao Salud Rosas isoniazid rifampin Villa Treatment outcome resistance amplification Objective. To determine rates of drug resistance in new cases of pulmonary tuberculosis in a region with a high burden of the disease. Materials and methods. New case suspects were referred for drug susceptibility testing. Results. 28.9% of new cases were resistant to at least one first line drug; 3.9% had a multidrug-resistant strain, 15.6% a monoresistant strain and 9.4% a polyresistant strain. Conclusion. Our rate of drug resistant tuberculosis in new cases is very high; this has important clinical implications, since even monoresistance can have a negative impact on the outcome of new cases treated empirically with a six month regimen. C, Laniado-Laborín R, Oceguera-Palao L. Farmacorresistencia en casos nuevos en una región con alta carga de tuberculosis. Un problema crítico. Salud Publica Mex 2015;57:177-179. 2015 artículo científico 0036-3634 https://www.redalyc.org/articulo.oa?id=10636867009 en http://www.redalyc.org/revista.oa?id=106 Salud Pública de México application/pdf Instituto Nacional de Salud Pública Salud Pública de México (México) Num.2 Vol.57 |
| title | Primary drug resistance in a region with high burden of tuberculosis. A critical problem |
| topic | Salud Rosas isoniazid rifampin Villa Treatment outcome resistance amplification |
| url | https://www.redalyc.org/articulo.oa?id=10636867009 |