Disease and weight loss: a prospective study of middle-aged and older adults in Costa Rica and England
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| Natura: | Artículo científico |
| Lingua: | en |
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Instituto Nacional de Salud Pública
2015
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| _version_ | 1876431406751547392 |
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| author | Laura Blue |
| author_facet | Laura Blue |
| contents | Disease and weight loss: a prospective study of middle-aged and older adults in Costa Rica and England Laura Blue Noreen Goldman Luis Rosero-Bixby Salud England Costa Rica Weight loss body mass index diabetes mellitus Objective. To determine whether disease predicts weight loss in population-based studies, as this may confound the relationship between weight and mortality. Materials and methods. We used longitudinal data from the Costa Rican Longevity and Healthy Aging Study (CRELES) and the English Longitudinal Study of Ageing (ELSA). We defined two overlapping outcomes of measured weight loss between waves: >1.0 point of body mass index (BMI) and >2.0 BMI points. Logistic regression models estimated the associations with disease, adjusting for age (range 52-79), sex, smoking, and initial BMI. Results. In ELSA, onset of diabetes, cancer, or lung disease is associated with loss >2.0 points (respectively, OR=2.25 [95%CI: 1.34-3.80]; OR=2.70 [95%CI: 1.49-4.89]; OR=1.82 [95%CI: 1.02-3.26]). In CRELES, disease-onset reports are not associated with weight loss at 5% significance, but statistical power to detect associations is poor. Conclusion. Although it is known that some diseases cause weight loss, at the population level these associations vary considerably across samples. 2015 artículo científico 0036-3634 https://www.redalyc.org/articulo.oa?id=10641192003 en http://www.redalyc.org/revista.oa?id=106 Salud Pública de México application/pdf Instituto Nacional de Salud Pública Salud Pública de México (México) Num.4 Vol.57 |
| format | Artículo científico |
| id | redalyc_10641192003 |
| institution | Redalyc |
| language | en |
| publishDate | 2015 |
| publisher | Instituto Nacional de Salud Pública |
| spellingShingle | Disease and weight loss: a prospective study of middle-aged and older adults in Costa Rica and England Laura Blue Salud England Costa Rica Weight loss body mass index diabetes mellitus Disease and weight loss: a prospective study of middle-aged and older adults in Costa Rica and England Laura Blue Noreen Goldman Luis Rosero-Bixby Salud England Costa Rica Weight loss body mass index diabetes mellitus Objective. To determine whether disease predicts weight loss in population-based studies, as this may confound the relationship between weight and mortality. Materials and methods. We used longitudinal data from the Costa Rican Longevity and Healthy Aging Study (CRELES) and the English Longitudinal Study of Ageing (ELSA). We defined two overlapping outcomes of measured weight loss between waves: >1.0 point of body mass index (BMI) and >2.0 BMI points. Logistic regression models estimated the associations with disease, adjusting for age (range 52-79), sex, smoking, and initial BMI. Results. In ELSA, onset of diabetes, cancer, or lung disease is associated with loss >2.0 points (respectively, OR=2.25 [95%CI: 1.34-3.80]; OR=2.70 [95%CI: 1.49-4.89]; OR=1.82 [95%CI: 1.02-3.26]). In CRELES, disease-onset reports are not associated with weight loss at 5% significance, but statistical power to detect associations is poor. Conclusion. Although it is known that some diseases cause weight loss, at the population level these associations vary considerably across samples. 2015 artículo científico 0036-3634 https://www.redalyc.org/articulo.oa?id=10641192003 en http://www.redalyc.org/revista.oa?id=106 Salud Pública de México application/pdf Instituto Nacional de Salud Pública Salud Pública de México (México) Num.4 Vol.57 |
| title | Disease and weight loss: a prospective study of middle-aged and older adults in Costa Rica and England |
| topic | Salud England Costa Rica Weight loss body mass index diabetes mellitus |
| url | https://www.redalyc.org/articulo.oa?id=10641192003 |