Efecto de la administración semanal de ácido fólico sobre los valores sanguíneos
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| Format: | Artículo científico |
| Sprache: | en |
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Instituto Nacional de Salud Pública
2001
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| _version_ | 1876462117056413696 |
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| author | Laura E. Martínez |
| author_facet | Laura E. Martínez |
| contents | Efecto de la administración semanal de ácido fólico sobre los valores sanguíneos Laura E. Martínez Carmen Limón María Alejandra Sánchez Ramón Valdez Jesús Z. Villarreal Salud Mexico neural tube defects prevention & control Key words: folic acid Objective. To evaluate the effect of weekly administrationof 5 mg. folic acid (FA) intake on folic acid blood levels.Material and methods. This concurrent comparative studywas conducted in 1998, in urban and rural areas of NuevoLeon State, Mexico. The study population consisted of 74women who delivered a child during 1997, 39 of whom hada child with a neural tube defect. Women were given 5 mg.of folic acid, weekly for 3 months. Blood levels of folic acidwere determined by radioimmunoassay (RIA) at baseline,and a week after taking the last folic acid dose. Data arepresented as means and standard deviations. Results.Ninety per cent of the women had significantly increasedfolic acid intraerythrocytary blood levels. Red cell folateincreased from 150.49 ± 31.17 ng/ml to 184.21 ± 35.53ng/ml (p<0.005). Plasma folate increased from 5.93 ± 1.98ng/ml a 7.03 ± 2.5 ng/ml (p<0.05). Eighty-two per cent ofwomen reached intracellular levels above 160 ng/ml.Conclusions. The weekly administration of folic acid is asimple and efficient method that could be used tosupplement this vitamin to low-income populations.TheEnglish version of this paper is available at: http://www.insp.mx/salud/index.html 2001 artículo científico 0036-3634 https://www.redalyc.org/articulo.oa?id=10643206 en http://www.redalyc.org/revista.oa?id=106 Salud Pública de México application/pdf Instituto Nacional de Salud Pública Salud Pública de México (México) Num.2 Vol.43 |
| format | Artículo científico |
| id | redalyc_10643206 |
| institution | Redalyc |
| language | en |
| publishDate | 2001 |
| publisher | Instituto Nacional de Salud Pública |
| spellingShingle | Efecto de la administración semanal de ácido fólico sobre los valores sanguíneos Laura E. Martínez Salud Mexico neural tube defects prevention & control Key words: folic acid Efecto de la administración semanal de ácido fólico sobre los valores sanguíneos Laura E. Martínez Carmen Limón María Alejandra Sánchez Ramón Valdez Jesús Z. Villarreal Salud Mexico neural tube defects prevention & control Key words: folic acid Objective. To evaluate the effect of weekly administrationof 5 mg. folic acid (FA) intake on folic acid blood levels.Material and methods. This concurrent comparative studywas conducted in 1998, in urban and rural areas of NuevoLeon State, Mexico. The study population consisted of 74women who delivered a child during 1997, 39 of whom hada child with a neural tube defect. Women were given 5 mg.of folic acid, weekly for 3 months. Blood levels of folic acidwere determined by radioimmunoassay (RIA) at baseline,and a week after taking the last folic acid dose. Data arepresented as means and standard deviations. Results.Ninety per cent of the women had significantly increasedfolic acid intraerythrocytary blood levels. Red cell folateincreased from 150.49 ± 31.17 ng/ml to 184.21 ± 35.53ng/ml (p<0.005). Plasma folate increased from 5.93 ± 1.98ng/ml a 7.03 ± 2.5 ng/ml (p<0.05). Eighty-two per cent ofwomen reached intracellular levels above 160 ng/ml.Conclusions. The weekly administration of folic acid is asimple and efficient method that could be used tosupplement this vitamin to low-income populations.TheEnglish version of this paper is available at: http://www.insp.mx/salud/index.html 2001 artículo científico 0036-3634 https://www.redalyc.org/articulo.oa?id=10643206 en http://www.redalyc.org/revista.oa?id=106 Salud Pública de México application/pdf Instituto Nacional de Salud Pública Salud Pública de México (México) Num.2 Vol.43 |
| title | Efecto de la administración semanal de ácido fólico sobre los valores sanguíneos |
| topic | Salud Mexico neural tube defects prevention & control Key words: folic acid |
| url | https://www.redalyc.org/articulo.oa?id=10643206 |