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| Formato: | Artículo científico |
| Lenguaje: | en |
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Sociedade Portuguesa de Pneumologia
2014
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| Acceso en línea: | https://www.redalyc.org/articulo.oa?id=169731333009 |
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- Chronic granulomatous disease associated with common variable immunodeficiency - 2 clinical cases C. Pacheco A. Morais R. Rolo L. Ferreira R. Nabiço J. Cunha Medicina Granulomas Sarcoidosis Granulomatous disease Common variable immunodeficiency Introduction: Chronic granulomatous disease associated with common variable immunodefi- ciency (GD-CVID), although well documented, is rare. Granulomatous lesions can affect several organs and are histologically indistinguishable from sarcoidosis. Clinical cases: Case 1: A 39-year-old male patient with CVID, asymptomatic although with thrombocytopenia and mediastinal-hilar adenopathies. GD-CVID was diagnosed by bone marrow biopsy. Progressive clinical and radiological improvement was obtained with corticotherapy. Case 2: A 38-year-old male patient with CVID, suffered from asthenia, anorexia, myalgia, lower limbs edemas, and dry cough. He had mediastinal and bilateral hilar adenopathies within which biopsy revealed non-necrotizing granulomatous infiltrate. A spontaneous resolution was detected after 9 months of evolution. Conclusion: GD-CVID is rare and can mimetize other pathologies, namely, sarcoidosis; it should therefore be publicized and discussed so that it becomes a general clinical knowledge. 2014 artículo científico 0873-2159 https://www.redalyc.org/articulo.oa?id=169731333009 en http://www.redalyc.org/revista.oa?id=1697 Revista Portuguesa de Pneumología application/pdf Sociedade Portuguesa de Pneumologia Revista Portuguesa de Pneumología (Portugal) Num.4 Vol.20