Renoprotective effects of 3 HMG reductase blockers in elderly patients with acute coronary syndrome undergoing revascularization through percutaneous coronary intervention
Fuente:
Redalyc
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Artículo científico |
| Sprache: | en |
| Veröffentlicht: |
Sociedad Latinoamericana de Hipertensión
2019
|
| Schlagworte: | |
| Online-Zugang: | |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| _version_ | 1876442246381830144 |
|---|---|
| author | Olga A. Osipova |
| author_facet | Olga A. Osipova |
| contents | Renoprotective effects of 3 HMG reductase blockers in elderly patients with acute coronary syndrome undergoing revascularization through percutaneous coronary intervention Olga A. Osipova Nina I. Zhernakova Ekaterina V Dobromirova Andrei I. Golovin Medicina statins chronic kidney disease Acute coronary syndrome This literature review presents current data on statins as anti-inflammatory agents in atherogenesis. Molecular mechanisms responsible for the anti-inflammatory effects of statins and clinical data on the non-lipid-lowering, anti-inflammatory effect of statins on cardiovascular outcomes are described. Analyzed the results of several randomized clinical trials, including GREACE, ALLIANCE, TNT, PLANET I, PLANET II, as well as other studies and meta-analyses. Since, cardiovascular events and renal dysfunction are associated with increased morbidity, lower quality of life and higher mortality rates. The results of statin therapy in recent large randomized clinical trials are also discussed. Prospects for further studies to compare the clinical efficacy of statins in situations where there is a risk of kidney damage are discussed. The question of preliminary (load) administration of statins in patients with the acute coronary syndrome with ST-elevation remains relevant (STEMI). 2019 artículo científico 1856-4550 https://www.redalyc.org/articulo.oa?id=170263002021 https://www.redalyc.org/journal/1702/170263002021/ https://www.redalyc.org/journal/1702/170263002021/html/ https://www.redalyc.org/journal/1702/170263002021/170263002021.epub https://www.redalyc.org/journal/1702/170263002021/movil en http://www.redalyc.org/revista.oa?id=1702 Revista Latinoamericana de Hipertensión application/pdf Sociedad Latinoamericana de Hipertensión Revista Latinoamericana de Hipertensión (República Bolivariana de Venezuela) Num.4 Vol.14 |
| format | Artículo científico |
| id | redalyc_170263002021 |
| institution | Redalyc |
| language | en |
| publishDate | 2019 |
| publisher | Sociedad Latinoamericana de Hipertensión |
| spellingShingle | Renoprotective effects of 3 HMG reductase blockers in elderly patients with acute coronary syndrome undergoing revascularization through percutaneous coronary intervention Olga A. Osipova Medicina statins chronic kidney disease Acute coronary syndrome Renoprotective effects of 3 HMG reductase blockers in elderly patients with acute coronary syndrome undergoing revascularization through percutaneous coronary intervention Olga A. Osipova Nina I. Zhernakova Ekaterina V Dobromirova Andrei I. Golovin Medicina statins chronic kidney disease Acute coronary syndrome This literature review presents current data on statins as anti-inflammatory agents in atherogenesis. Molecular mechanisms responsible for the anti-inflammatory effects of statins and clinical data on the non-lipid-lowering, anti-inflammatory effect of statins on cardiovascular outcomes are described. Analyzed the results of several randomized clinical trials, including GREACE, ALLIANCE, TNT, PLANET I, PLANET II, as well as other studies and meta-analyses. Since, cardiovascular events and renal dysfunction are associated with increased morbidity, lower quality of life and higher mortality rates. The results of statin therapy in recent large randomized clinical trials are also discussed. Prospects for further studies to compare the clinical efficacy of statins in situations where there is a risk of kidney damage are discussed. The question of preliminary (load) administration of statins in patients with the acute coronary syndrome with ST-elevation remains relevant (STEMI). 2019 artículo científico 1856-4550 https://www.redalyc.org/articulo.oa?id=170263002021 https://www.redalyc.org/journal/1702/170263002021/ https://www.redalyc.org/journal/1702/170263002021/html/ https://www.redalyc.org/journal/1702/170263002021/170263002021.epub https://www.redalyc.org/journal/1702/170263002021/movil en http://www.redalyc.org/revista.oa?id=1702 Revista Latinoamericana de Hipertensión application/pdf Sociedad Latinoamericana de Hipertensión Revista Latinoamericana de Hipertensión (República Bolivariana de Venezuela) Num.4 Vol.14 |
| title | Renoprotective effects of 3 HMG reductase blockers in elderly patients with acute coronary syndrome undergoing revascularization through percutaneous coronary intervention |
| topic | Medicina statins chronic kidney disease Acute coronary syndrome |
| url | https://www.redalyc.org/articulo.oa?id=170263002021 https://www.redalyc.org/journal/1702/170263002021/ https://www.redalyc.org/journal/1702/170263002021/html/ https://www.redalyc.org/journal/1702/170263002021/170263002021.epub https://www.redalyc.org/journal/1702/170263002021/movil |