Relationship between changes in heart rate variability indices and blood glucose control in Type 2 Diabetes Mellitus
Fuente:
Redalyc
Salvato in:
| Autore principale: | |
|---|---|
| Natura: | Artículo científico |
| Lingua: | en |
| Pubblicazione: |
Sociedad Latinoamericana de Hipertensión
2019
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1876478241689042944 |
|---|---|
| author | Mostafa Bahremand |
| author_facet | Mostafa Bahremand |
| contents | Relationship between changes in heart rate variability indices and blood glucose control in Type 2 Diabetes Mellitus Mostafa Bahremand Karoon Shahebrahimi Fatemeh Seyedi Nafiseh Montazeri Medicina hemoglobin A1C Diabetes mellitus autonomic nervous system heart rate variability (HRV) Diabetes mellitus (DM) is one of the most common health problems in the community. DM is associated with pathologic changes in the cardiovascular system due to alterations in the autonomic nervous system (ANS). Dysfunction of the cardiovascular ANS can lead to fatal arrhythmias and sudden death. The aim of this study was to investigate the relationship between changes in heart rate variability (HRV) indices and blood glucose control status in patients with type 2 DM. Patients with type 2 DM who presented to our university Diabetes Clinic were eligible to be included. Fasting blood glucose (FBG), 2-hour postprandial blood glucose test (2PPG), and hemoglobin A1C (HbA1C) were measured. According to the HbA1C the patients were categorized as euglycemia (HbA1C <7%) and poorly controlled DM (HbA1C >7%). HRV indices were determined by 24-hour Holter monitoring. There were 41 patients with euglycemia and 39 patients whose blood glucose was poorly controlled. pNN, SDANN, and SDNN indices were significantly higher in the euglycemia group than in the group with poorly controlled glucose. There was significant and inverse correlation between pNN, SDANN, and SDNN with serum levels of HBA1C. However, no significant correlation was observed between FBS and 2PPG with HRV indices. HRV indices were significantly lower in diabetic patients with poorly controlled blood glucose when compared to diabetics with good control of blood glucose. These findings reflect dysfunction of the ANS in patents with poorly controlled blood glucose. 2019 artículo científico 1856-4550 https://www.redalyc.org/articulo.oa?id=170263176014 https://www.redalyc.org/journal/1702/170263176014/ https://www.redalyc.org/journal/1702/170263176014/html/ https://www.redalyc.org/journal/1702/170263176014/170263176014.epub https://www.redalyc.org/journal/1702/170263176014/movil en http://www.redalyc.org/revista.oa?id=1702 Revista Latinoamericana de Hipertensión application/pdf Sociedad Latinoamericana de Hipertensión Revista Latinoamericana de Hipertensión (República Bolivariana de Venezuela) Num.3 Vol.14 |
| format | Artículo científico |
| id | redalyc_170263176014 |
| institution | Redalyc |
| language | en |
| publishDate | 2019 |
| publisher | Sociedad Latinoamericana de Hipertensión |
| spellingShingle | Relationship between changes in heart rate variability indices and blood glucose control in Type 2 Diabetes Mellitus Mostafa Bahremand Medicina hemoglobin A1C Diabetes mellitus autonomic nervous system heart rate variability (HRV) Relationship between changes in heart rate variability indices and blood glucose control in Type 2 Diabetes Mellitus Mostafa Bahremand Karoon Shahebrahimi Fatemeh Seyedi Nafiseh Montazeri Medicina hemoglobin A1C Diabetes mellitus autonomic nervous system heart rate variability (HRV) Diabetes mellitus (DM) is one of the most common health problems in the community. DM is associated with pathologic changes in the cardiovascular system due to alterations in the autonomic nervous system (ANS). Dysfunction of the cardiovascular ANS can lead to fatal arrhythmias and sudden death. The aim of this study was to investigate the relationship between changes in heart rate variability (HRV) indices and blood glucose control status in patients with type 2 DM. Patients with type 2 DM who presented to our university Diabetes Clinic were eligible to be included. Fasting blood glucose (FBG), 2-hour postprandial blood glucose test (2PPG), and hemoglobin A1C (HbA1C) were measured. According to the HbA1C the patients were categorized as euglycemia (HbA1C <7%) and poorly controlled DM (HbA1C >7%). HRV indices were determined by 24-hour Holter monitoring. There were 41 patients with euglycemia and 39 patients whose blood glucose was poorly controlled. pNN, SDANN, and SDNN indices were significantly higher in the euglycemia group than in the group with poorly controlled glucose. There was significant and inverse correlation between pNN, SDANN, and SDNN with serum levels of HBA1C. However, no significant correlation was observed between FBS and 2PPG with HRV indices. HRV indices were significantly lower in diabetic patients with poorly controlled blood glucose when compared to diabetics with good control of blood glucose. These findings reflect dysfunction of the ANS in patents with poorly controlled blood glucose. 2019 artículo científico 1856-4550 https://www.redalyc.org/articulo.oa?id=170263176014 https://www.redalyc.org/journal/1702/170263176014/ https://www.redalyc.org/journal/1702/170263176014/html/ https://www.redalyc.org/journal/1702/170263176014/170263176014.epub https://www.redalyc.org/journal/1702/170263176014/movil en http://www.redalyc.org/revista.oa?id=1702 Revista Latinoamericana de Hipertensión application/pdf Sociedad Latinoamericana de Hipertensión Revista Latinoamericana de Hipertensión (República Bolivariana de Venezuela) Num.3 Vol.14 |
| title | Relationship between changes in heart rate variability indices and blood glucose control in Type 2 Diabetes Mellitus |
| topic | Medicina hemoglobin A1C Diabetes mellitus autonomic nervous system heart rate variability (HRV) |
| url | https://www.redalyc.org/articulo.oa?id=170263176014 https://www.redalyc.org/journal/1702/170263176014/ https://www.redalyc.org/journal/1702/170263176014/html/ https://www.redalyc.org/journal/1702/170263176014/170263176014.epub https://www.redalyc.org/journal/1702/170263176014/movil |