Investigating the importance and causes of rheumatoid arthritis and its effective treatments: a review study
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| Format: | Artículo científico |
| Language: | en |
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Sociedad Latinoamericana de Hipertensión
2020
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| _version_ | 1876474739222904832 |
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| author | Sajad Hassanzadeh |
| author_facet | Sajad Hassanzadeh |
| contents | Investigating the importance and causes of rheumatoid arthritis and its effective treatments: a review study Sajad Hassanzadeh Mohammad Gholamnezhad Medicina RA genetics treatment environmental factors Rheumatoid arthritis (RA) is among the most important chronic diseases that can cause joint destruction and disability, especially in the adulthood. It is a progressive chronic autoimmune inflammatory disease with variable clinical symptoms, characterized by mild to severe inflammation of the joints that can result in pain, dryness and joint destruction along with joint malformations and disability. Besides its physical effects, it can also affect one's mental state and cause mental illnesses, such as depression, given its permanent changes in activity level and lifestyle. Therefore, due to the importance of this debilitating disease, the present study aimed to study the causes of RA and its effective treatments. The results showed that the most common cause of RA is genetic-related. However, genetic risk factor is not fully responsible for the disease and environmental factors have been reported to be effective. Although there has been a wide variety of studies on treatment of RA, no definitive treatments have been reported for the disease so far. The most commonly used treatment approaches for this disease are rest and general treatments, pharmacotherapy, hydrocortisone intra-articular injection, physiotherapy, occupational therapy and surgery. Rest is supposed to be effective, especially in the early stages of the disease and during the recurrence periods. Overall, the goal of non-pharmacological treatments is to reduce pressure on the joint. According to various studies, aspirin and non-steroidal anti-inflammatory drugs (indomethacin, ibuprofen, naproxen, and piroxicam) are the most commonly used drugs in the treatment of RA (especially in the early stages). 2020 artículo científico 1856-4550 https://www.redalyc.org/articulo.oa?id=170265473011 https://www.redalyc.org/journal/1702/170265473011/ https://www.redalyc.org/journal/1702/170265473011/html/ https://www.redalyc.org/journal/1702/170265473011/170265473011.epub https://www.redalyc.org/journal/1702/170265473011/movil https://doi.org/10.5281/zenodo.4074226 en http://www.redalyc.org/revista.oa?id=1702 Revista Latinoamericana de Hipertensión application/pdf Sociedad Latinoamericana de Hipertensión Revista Latinoamericana de Hipertensión (República Bolivariana de Venezuela) Num.1 Vol.15 |
| format | Artículo científico |
| id | redalyc_170265473011 |
| institution | Redalyc |
| language | en |
| publishDate | 2020 |
| publisher | Sociedad Latinoamericana de Hipertensión |
| spellingShingle | Investigating the importance and causes of rheumatoid arthritis and its effective treatments: a review study Sajad Hassanzadeh Medicina RA genetics treatment environmental factors Investigating the importance and causes of rheumatoid arthritis and its effective treatments: a review study Sajad Hassanzadeh Mohammad Gholamnezhad Medicina RA genetics treatment environmental factors Rheumatoid arthritis (RA) is among the most important chronic diseases that can cause joint destruction and disability, especially in the adulthood. It is a progressive chronic autoimmune inflammatory disease with variable clinical symptoms, characterized by mild to severe inflammation of the joints that can result in pain, dryness and joint destruction along with joint malformations and disability. Besides its physical effects, it can also affect one's mental state and cause mental illnesses, such as depression, given its permanent changes in activity level and lifestyle. Therefore, due to the importance of this debilitating disease, the present study aimed to study the causes of RA and its effective treatments. The results showed that the most common cause of RA is genetic-related. However, genetic risk factor is not fully responsible for the disease and environmental factors have been reported to be effective. Although there has been a wide variety of studies on treatment of RA, no definitive treatments have been reported for the disease so far. The most commonly used treatment approaches for this disease are rest and general treatments, pharmacotherapy, hydrocortisone intra-articular injection, physiotherapy, occupational therapy and surgery. Rest is supposed to be effective, especially in the early stages of the disease and during the recurrence periods. Overall, the goal of non-pharmacological treatments is to reduce pressure on the joint. According to various studies, aspirin and non-steroidal anti-inflammatory drugs (indomethacin, ibuprofen, naproxen, and piroxicam) are the most commonly used drugs in the treatment of RA (especially in the early stages). 2020 artículo científico 1856-4550 https://www.redalyc.org/articulo.oa?id=170265473011 https://www.redalyc.org/journal/1702/170265473011/ https://www.redalyc.org/journal/1702/170265473011/html/ https://www.redalyc.org/journal/1702/170265473011/170265473011.epub https://www.redalyc.org/journal/1702/170265473011/movil https://doi.org/10.5281/zenodo.4074226 en http://www.redalyc.org/revista.oa?id=1702 Revista Latinoamericana de Hipertensión application/pdf Sociedad Latinoamericana de Hipertensión Revista Latinoamericana de Hipertensión (República Bolivariana de Venezuela) Num.1 Vol.15 |
| title | Investigating the importance and causes of rheumatoid arthritis and its effective treatments: a review study |
| topic | Medicina RA genetics treatment environmental factors |
| url | https://www.redalyc.org/articulo.oa?id=170265473011 https://www.redalyc.org/journal/1702/170265473011/ https://www.redalyc.org/journal/1702/170265473011/html/ https://www.redalyc.org/journal/1702/170265473011/170265473011.epub https://www.redalyc.org/journal/1702/170265473011/movil https://doi.org/10.5281/zenodo.4074226 |