Caracterización funcional y localización del receptor GM-CSF en espermatozoides bovinos
Fuente:
Redalyc
Salvato in:
| Autore principale: | |
|---|---|
| Natura: | Artículo científico |
| Lingua: | es |
| Pubblicazione: |
Universidad Austral de Chile
2003
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1876479955280330752 |
|---|---|
| author | L. T. VILANOVA |
| author_facet | L. T. VILANOVA |
| contents | Caracterización funcional y localización del receptor GM-CSF en espermatozoides bovinos L. T. VILANOVA M. C. RAUCH A. ZAMBRANO M. BRITO E. WERNER I. I. CONCHA Veterinaria GM CSFr sperm motility sperm physiology The granulocyte-macrophage colony stimulating factor (GM-CSF) is a pleiotropic cytokine with the main function of regulating the proliferation and differentiation of myeloid precursor cells as well as to stimulate the functioning of mature mononuclear granulocytes and phagocytes. Its receptor is a glycoprotein formed by two subunits, a and ß, and it is expressed in precursor and mature myeloid cells, as well as in some nonhematopoietic cells. We have recently demonstrated that bull spermatozoa express functional GM-CSF receptors that signal an increased glucose and vitamin C uptake. The presence of GM-CSF receptor in epididymal and ejaculated spermatozoa was determined in this study and the a subunit was found in the acrosome and tail of the spermatozoa whilst the ß subunit was restricted to the tail. Computer assisted sperm analysis (CASA) demonstrated that the addition of GM-CSF to capacitated sperm in the presence of fructose increased the patterns of sperm motility in the majority of the variables analysed. Altogether, these findings suggest that GM-CSF is a key molecule to the better understanding of sperm physiology 2003 artículo científico 0301-732X https://www.redalyc.org/articulo.oa?id=173013751002 es http://www.redalyc.org/revista.oa?id=1730 Archivos de Medicina Veterinaria application/pdf Universidad Austral de Chile Archivos de Medicina Veterinaria (Chile) Num.2 Vol.35 |
| format | Artículo científico |
| id | redalyc_173013751002 |
| institution | Redalyc |
| language | es |
| publishDate | 2003 |
| publisher | Universidad Austral de Chile |
| spellingShingle | Caracterización funcional y localización del receptor GM-CSF en espermatozoides bovinos L. T. VILANOVA Veterinaria GM CSFr sperm motility sperm physiology Caracterización funcional y localización del receptor GM-CSF en espermatozoides bovinos L. T. VILANOVA M. C. RAUCH A. ZAMBRANO M. BRITO E. WERNER I. I. CONCHA Veterinaria GM CSFr sperm motility sperm physiology The granulocyte-macrophage colony stimulating factor (GM-CSF) is a pleiotropic cytokine with the main function of regulating the proliferation and differentiation of myeloid precursor cells as well as to stimulate the functioning of mature mononuclear granulocytes and phagocytes. Its receptor is a glycoprotein formed by two subunits, a and ß, and it is expressed in precursor and mature myeloid cells, as well as in some nonhematopoietic cells. We have recently demonstrated that bull spermatozoa express functional GM-CSF receptors that signal an increased glucose and vitamin C uptake. The presence of GM-CSF receptor in epididymal and ejaculated spermatozoa was determined in this study and the a subunit was found in the acrosome and tail of the spermatozoa whilst the ß subunit was restricted to the tail. Computer assisted sperm analysis (CASA) demonstrated that the addition of GM-CSF to capacitated sperm in the presence of fructose increased the patterns of sperm motility in the majority of the variables analysed. Altogether, these findings suggest that GM-CSF is a key molecule to the better understanding of sperm physiology 2003 artículo científico 0301-732X https://www.redalyc.org/articulo.oa?id=173013751002 es http://www.redalyc.org/revista.oa?id=1730 Archivos de Medicina Veterinaria application/pdf Universidad Austral de Chile Archivos de Medicina Veterinaria (Chile) Num.2 Vol.35 |
| title | Caracterización funcional y localización del receptor GM-CSF en espermatozoides bovinos |
| topic | Veterinaria GM CSFr sperm motility sperm physiology |
| url | https://www.redalyc.org/articulo.oa?id=173013751002 |