Efecto del selenato de bario inyectable sobre la actividad de Glutation peroxidasa en caballos a pastoreo
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| Format: | Artículo científico |
| Language: | es |
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Universidad Austral de Chile
2004
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| _version_ | 1876465039644295168 |
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| author | O. Araya |
| author_facet | O. Araya |
| contents | Efecto del selenato de bario inyectable sobre la actividad de Glutation peroxidasa en caballos a pastoreo O. Araya R. Urzua H. Bustamante Veterinaria Equine selenium steatosis barium selenate The aims of this study was to measure the response to i.m. inyection of barium selenate (Deposel) using erythrocytic glutathion peroxidase (GSH-Px) activity as indicator of selenium status. Local tissue reaction in the injection site was also measured. Fourteen Chilean Criollo horses, from two to twenty years old, low erythrocytic GSH-Px activity and under pasture feeding were used. They were divided into two groups: A (n=8) received a single dose of 0.5 mg/kg bw of barium selenate and B (n=6) received a placebo. Heparinizated blood was obtained at the beginning of experiment and at 30, 60, 90 and 180 days after treatment. Local tissue reaction was evaluated according to reaction size, discomfort on palpation, local temperature and lameness. Erythrocytic GSH-Px activity of the A group incremented thirty days after treatment, reaching the minimum value of the reference range ( 100 mU/mgHb). However, this increment was not statistically significant (p0.05), but difference between treated (A) and non treated (B) groups were statistically significant (p<0.05). GSH-Px activity incremented significativelly 60, 90 and 180 days after treatment in the treated group, and differences between treated and non treated groups were also significantly (p<0.05) at these time. Treated horses showed only barely discomfort on palpation and a light local temperature elevation at injection site, but both of them disappeared four days after treatment. It can be concluded that a single i.m. injection of 0.5 mg/kg bw of barium selenate, will increment and maintain erithrocytic GSH-Px activity in the reference range for at least 180 days in horses. Besides, i.m. injection of barium selenate does not produce adverse reactions clinically detected at the injection site. Palabras claves: equino, selenio, esteatosis, selenato de bario. 2004 artículo científico 0301-732X https://www.redalyc.org/articulo.oa?id=173013753003 es http://www.redalyc.org/revista.oa?id=1730 Archivos de Medicina Veterinaria application/pdf Universidad Austral de Chile Archivos de Medicina Veterinaria (Chile) Num.1 Vol.XXXVI |
| format | Artículo científico |
| id | redalyc_173013753003 |
| institution | Redalyc |
| language | es |
| publishDate | 2004 |
| publisher | Universidad Austral de Chile |
| spellingShingle | Efecto del selenato de bario inyectable sobre la actividad de Glutation peroxidasa en caballos a pastoreo O. Araya Veterinaria Equine selenium steatosis barium selenate Efecto del selenato de bario inyectable sobre la actividad de Glutation peroxidasa en caballos a pastoreo O. Araya R. Urzua H. Bustamante Veterinaria Equine selenium steatosis barium selenate The aims of this study was to measure the response to i.m. inyection of barium selenate (Deposel) using erythrocytic glutathion peroxidase (GSH-Px) activity as indicator of selenium status. Local tissue reaction in the injection site was also measured. Fourteen Chilean Criollo horses, from two to twenty years old, low erythrocytic GSH-Px activity and under pasture feeding were used. They were divided into two groups: A (n=8) received a single dose of 0.5 mg/kg bw of barium selenate and B (n=6) received a placebo. Heparinizated blood was obtained at the beginning of experiment and at 30, 60, 90 and 180 days after treatment. Local tissue reaction was evaluated according to reaction size, discomfort on palpation, local temperature and lameness. Erythrocytic GSH-Px activity of the A group incremented thirty days after treatment, reaching the minimum value of the reference range ( 100 mU/mgHb). However, this increment was not statistically significant (p0.05), but difference between treated (A) and non treated (B) groups were statistically significant (p<0.05). GSH-Px activity incremented significativelly 60, 90 and 180 days after treatment in the treated group, and differences between treated and non treated groups were also significantly (p<0.05) at these time. Treated horses showed only barely discomfort on palpation and a light local temperature elevation at injection site, but both of them disappeared four days after treatment. It can be concluded that a single i.m. injection of 0.5 mg/kg bw of barium selenate, will increment and maintain erithrocytic GSH-Px activity in the reference range for at least 180 days in horses. Besides, i.m. injection of barium selenate does not produce adverse reactions clinically detected at the injection site. Palabras claves: equino, selenio, esteatosis, selenato de bario. 2004 artículo científico 0301-732X https://www.redalyc.org/articulo.oa?id=173013753003 es http://www.redalyc.org/revista.oa?id=1730 Archivos de Medicina Veterinaria application/pdf Universidad Austral de Chile Archivos de Medicina Veterinaria (Chile) Num.1 Vol.XXXVI |
| title | Efecto del selenato de bario inyectable sobre la actividad de Glutation peroxidasa en caballos a pastoreo |
| topic | Veterinaria Equine selenium steatosis barium selenate |
| url | https://www.redalyc.org/articulo.oa?id=173013753003 |