Efficacy of cannabinoids in pharmacoresistant epilepsy: A narrative review of the literature
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| Format: | Artículo científico |
| Sprache: | en |
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Universidad de Antioquia
2020
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| author | Alexandra Ferreiros |
| author_facet | Alexandra Ferreiros |
| contents | Efficacy of cannabinoids in pharmacoresistant epilepsy: A narrative review of the literature Alexandra Ferreiros Elkin Beltrán-Carrascal Paula Restrepo Camila Pantoja Camilo Castañeda-Cardona Pieralessandro Lasalvia Laura Van Der Werf Daniel Nariño Diego Rosselli Medicina Review Cannabis Drug Resistant Epilepsy Epilepsy is a common neurological disorder that affects approximately 1% of the world’s pop7u-lation. About one third of those patients suffer from treatment-resistant epilepsy (TRE8), defined as failure to stop seizures despite adequate trials of at least two medications at therapeutic dosa-ges. There has been a growing interest in the development of novel antiepileptic drugs with diffe-rent mechanisms of action. This narrative review, based on 42 references retrieved from Scopus and Medline, discusses the scientific data from human and animal studies regarding the efficacy of cannabis-based treatment for epilepsy. Benefits have been described in preclinical and cli-nical studies in children, but ongoing research will clarify the real role of cannabinoids in TRE. 2020 reseña 0121-0793 https://www.redalyc.org/articulo.oa?id=180563251007 https://www.redalyc.org/journal/1805/180563251007/ https://www.redalyc.org/journal/1805/180563251007/html/ https://www.redalyc.org/journal/1805/180563251007/180563251007.epub https://www.redalyc.org/journal/1805/180563251007/movil 10.17533/udea.iatreia.42 en http://www.redalyc.org/revista.oa?id=1805 Iatreia application/pdf Universidad de Antioquia Iatreia (Colombia) Num.2 Vol.33 |
| format | Artículo científico |
| id | redalyc_180563251007 |
| institution | Redalyc |
| language | en |
| publishDate | 2020 |
| publisher | Universidad de Antioquia |
| spellingShingle | Efficacy of cannabinoids in pharmacoresistant epilepsy: A narrative review of the literature Alexandra Ferreiros Medicina Review Cannabis Drug Resistant Epilepsy Efficacy of cannabinoids in pharmacoresistant epilepsy: A narrative review of the literature Alexandra Ferreiros Elkin Beltrán-Carrascal Paula Restrepo Camila Pantoja Camilo Castañeda-Cardona Pieralessandro Lasalvia Laura Van Der Werf Daniel Nariño Diego Rosselli Medicina Review Cannabis Drug Resistant Epilepsy Epilepsy is a common neurological disorder that affects approximately 1% of the world’s pop7u-lation. About one third of those patients suffer from treatment-resistant epilepsy (TRE8), defined as failure to stop seizures despite adequate trials of at least two medications at therapeutic dosa-ges. There has been a growing interest in the development of novel antiepileptic drugs with diffe-rent mechanisms of action. This narrative review, based on 42 references retrieved from Scopus and Medline, discusses the scientific data from human and animal studies regarding the efficacy of cannabis-based treatment for epilepsy. Benefits have been described in preclinical and cli-nical studies in children, but ongoing research will clarify the real role of cannabinoids in TRE. 2020 reseña 0121-0793 https://www.redalyc.org/articulo.oa?id=180563251007 https://www.redalyc.org/journal/1805/180563251007/ https://www.redalyc.org/journal/1805/180563251007/html/ https://www.redalyc.org/journal/1805/180563251007/180563251007.epub https://www.redalyc.org/journal/1805/180563251007/movil 10.17533/udea.iatreia.42 en http://www.redalyc.org/revista.oa?id=1805 Iatreia application/pdf Universidad de Antioquia Iatreia (Colombia) Num.2 Vol.33 |
| title | Efficacy of cannabinoids in pharmacoresistant epilepsy: A narrative review of the literature |
| topic | Medicina Review Cannabis Drug Resistant Epilepsy |
| url | https://www.redalyc.org/articulo.oa?id=180563251007 https://www.redalyc.org/journal/1805/180563251007/ https://www.redalyc.org/journal/1805/180563251007/html/ https://www.redalyc.org/journal/1805/180563251007/180563251007.epub https://www.redalyc.org/journal/1805/180563251007/movil |