Serum and Cerebrospinal fluid levels of cooper, iron and zinc in patients with Ataxia type SCA-2 from the province of Holguín in Cuba
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| Format: | Artículo científico |
| Langue: | en |
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Centro Nacional de Investigaciones Científicas
2005
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| _version_ | 1876454820775198720 |
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| author | Consuelo de la C Gonzalez Triana |
| author_facet | Consuelo de la C Gonzalez Triana |
| contents | Serum and Cerebrospinal fluid levels of cooper, iron and zinc in patients with Ataxia type SCA-2 from the province of Holguín in Cuba Consuelo de la C Gonzalez Triana Gilberto Sánchez Alina Gonzalez-Quevedo René Delgado Luis Velázquez Julio César García Jacqueline García Somines Nereida Mantilla Gattorno Biología SCA iron zinc serum copper SCA-2 Ataxia constitutes a health problem for the province of Holguín and potentially for all Cuba. 757 persons in Cuba suffer this disease and almost 8000 descendents are at risk. The present work investigated serum and cerebrospinal fluid (CSF) copper (Cu), iron (Fe) and zinc (Zn) levels in 25 patients with SCA-2 Ataxia (14 men and 11 women) and in 30 neurologically normal persons (14 men and 16 women), employing atomic absorption techniques. A significant decrease of serum Zn concentration and CSF Cu, Fe and Zn levels were detected in patients with respect to controls. These results indicate an impairment of homeostasis for these important microelements in type SCA-2 Ataxia. These evidences support the application of new strategies for treating this disease. 2005 artículo científico 0253-5688 https://www.redalyc.org/articulo.oa?id=181220525113 en http://www.redalyc.org/revista.oa?id=1812 Revista CENIC. Ciencias Biológicas application/pdf Centro Nacional de Investigaciones Científicas Revista CENIC. Ciencias Biológicas (Cuba) Vol.36 |
| format | Artículo científico |
| id | redalyc_181220525113 |
| institution | Redalyc |
| language | en |
| publishDate | 2005 |
| publisher | Centro Nacional de Investigaciones Científicas |
| spellingShingle | Serum and Cerebrospinal fluid levels of cooper, iron and zinc in patients with Ataxia type SCA-2 from the province of Holguín in Cuba Consuelo de la C Gonzalez Triana Biología SCA iron zinc serum copper Serum and Cerebrospinal fluid levels of cooper, iron and zinc in patients with Ataxia type SCA-2 from the province of Holguín in Cuba Consuelo de la C Gonzalez Triana Gilberto Sánchez Alina Gonzalez-Quevedo René Delgado Luis Velázquez Julio César García Jacqueline García Somines Nereida Mantilla Gattorno Biología SCA iron zinc serum copper SCA-2 Ataxia constitutes a health problem for the province of Holguín and potentially for all Cuba. 757 persons in Cuba suffer this disease and almost 8000 descendents are at risk. The present work investigated serum and cerebrospinal fluid (CSF) copper (Cu), iron (Fe) and zinc (Zn) levels in 25 patients with SCA-2 Ataxia (14 men and 11 women) and in 30 neurologically normal persons (14 men and 16 women), employing atomic absorption techniques. A significant decrease of serum Zn concentration and CSF Cu, Fe and Zn levels were detected in patients with respect to controls. These results indicate an impairment of homeostasis for these important microelements in type SCA-2 Ataxia. These evidences support the application of new strategies for treating this disease. 2005 artículo científico 0253-5688 https://www.redalyc.org/articulo.oa?id=181220525113 en http://www.redalyc.org/revista.oa?id=1812 Revista CENIC. Ciencias Biológicas application/pdf Centro Nacional de Investigaciones Científicas Revista CENIC. Ciencias Biológicas (Cuba) Vol.36 |
| title | Serum and Cerebrospinal fluid levels of cooper, iron and zinc in patients with Ataxia type SCA-2 from the province of Holguín in Cuba |
| topic | Biología SCA iron zinc serum copper |
| url | https://www.redalyc.org/articulo.oa?id=181220525113 |