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| Format: | Artículo científico |
| Language: | en |
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Universidade Estadual de Maringá
2014
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| Online Access: | https://www.redalyc.org/articulo.oa?id=187132092014 |
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Table of Contents:
- Evaluation of quantitative parameters of Leydig cell in diabetic adults rats Alluanan Adelson do Nascimento Silva Jessica Santana de Oliveira Rodrigo Ribeiro de Oliveira Sílvia Regina Arruda de Moraes Valdemiro Amaro da Silva Junior Elizabeth Neves de Melo Biología testes Keywords morphometry streptozotocin interstitial cells The goal of present study was to evaluate the effects of diabetes on quantitative parameters of Leydig cells. Twelve adults Wistar rats were divi ded in: 1) Diabetic Group (DG), which was induced by a single intraperitoneal injection of streptozotocin (60 mg kg -1 of body weight); and 2) Control Group (CG), which received citrate buffer intraperitoneal. Af ter eight weeks of diabetic induction, the animals were weighted, anesthetized and te sticles were removed and routinely processed to paraffin embedded. Body weight (40%) and testicular weig ht (18%) of diabetic rats were sign ificantly lower than control group. Diabetic rats showed an increase in interstitial compartment but the tubular compartment did not differ. The individual volume of Leydig cells and nuclear di ameter were lower in DG. However, the population of these cells was increased. In conclusion, diabetes induced by streptozotocin in adult rats promoted alterations in testicular compartments and changes on volume, nuclear diameter and population of Leydig cells, compromising the testicular function. 2014 artículo científico 1679-9283 https://www.redalyc.org/articulo.oa?id=187132092014 en http://www.redalyc.org/revista.oa?id=1871 Acta Scientiarum. Biological Sciences application/pdf Universidade Estadual de Maringá Acta Scientiarum. Biological Sciences (Brasil) Num.4 Vol.36