Prolonged orocecal transit time is associated with small intestinal bacterial overgrowth in irritable bowel syndrome in a tertiary referral hospital in Brazil
Fuente:
Redalyc
Guardado en:
| Autor principal: | |
|---|---|
| Formato: | Artículo científico |
| Lenguaje: | en |
| Publicado: |
Sociedad Argentina de Gastroenterología
2016
|
| Materias: | |
| Acceso en línea: | |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| _version_ | 1876440109245530112 |
|---|---|
| author | Cristiane Kibune Nagasako |
| author_facet | Cristiane Kibune Nagasako |
| contents | Prolonged orocecal transit time is associated with small intestinal bacterial overgrowth in irritable bowel syndrome in a tertiary referral hospital in Brazil Cristiane Kibune Nagasako Sônia Letícia Silva Lorena Célia Regina Pavan Michelle Viviane Sá dos Santos Rondon Ciro Garcia Montes Maria Aparecida Mesquita Medicina orocecal transit time Irritable bowel syndrome small intestinal bacterial overgrowth Studies on small intestinal transit in irritable bowel syn drome (IBS) are scarce and inconclusive. The contribution of intestinal dysmotility to the development of small bowel bacterial overgrowth (SIBO) in these patients remains to be elucidated. The aims of this study were to assess the oroce cal transit time (OCTT) and the frequency of SIBO in IBS patients, the relationship between these two parameters, and their respective associations with clinical features, body mass index (BMI) and psychological distress. Methods. Ninety consecutive IBS patients were studied. All of them answered a structured questionnaire for demographic and clinical data. The presence of anxiety and depression was assessed by the Hospital Anxiety and Depression scale. Hydrogen breath test after lactulose ingestion (LHBT) and glucose hydrogen breath test (GHBT) were used for the assessment of OCTT and SIBO respectively. IBS group were compared to age matched healthy volunteers, recruited among the hospital staff (n = 25, OCTT and n = 20, GHBT). Results. OCTT in IBS patients (77 ± 36 min) was significantly higher than in controls (64 ± 40 min; p = 0.03). Individual analysis showed prolonged OCTT (> 80 min) in 28.9% of IBS pa tients, and SIBO in 15.5%. The only symptom significantly associated with SIBO was diarrhea (p = 0.03). In addition there was a significant relationship (p = 0.005) between SIBO and prolonged OCTT. OCTT was not associated (p > 0.05) with intestinal complaints, BMI, anxiety or depression. Conclusions. About one third of IBS patients present pro longed OCTT, indicating delayed small bowel transit. This abnormality appears to be a predisposing condition for the development of SIBO. SIBO is more frequent in IBS patients with diarrhea. 2016 artículo científico 2469-1119 https://www.redalyc.org/articulo.oa?id=199349172004 en http://www.redalyc.org/revista.oa?id=1993 Acta Gastroenterológica Latinoamericana application/pdf Sociedad Argentina de Gastroenterología Acta Gastroenterológica Latinoamericana (Argentina) Num.4 Vol.46 |
| format | Artículo científico |
| id | redalyc_199349172004 |
| institution | Redalyc |
| language | en |
| publishDate | 2016 |
| publisher | Sociedad Argentina de Gastroenterología |
| spellingShingle | Prolonged orocecal transit time is associated with small intestinal bacterial overgrowth in irritable bowel syndrome in a tertiary referral hospital in Brazil Cristiane Kibune Nagasako Medicina orocecal transit time Irritable bowel syndrome small intestinal bacterial overgrowth Prolonged orocecal transit time is associated with small intestinal bacterial overgrowth in irritable bowel syndrome in a tertiary referral hospital in Brazil Cristiane Kibune Nagasako Sônia Letícia Silva Lorena Célia Regina Pavan Michelle Viviane Sá dos Santos Rondon Ciro Garcia Montes Maria Aparecida Mesquita Medicina orocecal transit time Irritable bowel syndrome small intestinal bacterial overgrowth Studies on small intestinal transit in irritable bowel syn drome (IBS) are scarce and inconclusive. The contribution of intestinal dysmotility to the development of small bowel bacterial overgrowth (SIBO) in these patients remains to be elucidated. The aims of this study were to assess the oroce cal transit time (OCTT) and the frequency of SIBO in IBS patients, the relationship between these two parameters, and their respective associations with clinical features, body mass index (BMI) and psychological distress. Methods. Ninety consecutive IBS patients were studied. All of them answered a structured questionnaire for demographic and clinical data. The presence of anxiety and depression was assessed by the Hospital Anxiety and Depression scale. Hydrogen breath test after lactulose ingestion (LHBT) and glucose hydrogen breath test (GHBT) were used for the assessment of OCTT and SIBO respectively. IBS group were compared to age matched healthy volunteers, recruited among the hospital staff (n = 25, OCTT and n = 20, GHBT). Results. OCTT in IBS patients (77 ± 36 min) was significantly higher than in controls (64 ± 40 min; p = 0.03). Individual analysis showed prolonged OCTT (> 80 min) in 28.9% of IBS pa tients, and SIBO in 15.5%. The only symptom significantly associated with SIBO was diarrhea (p = 0.03). In addition there was a significant relationship (p = 0.005) between SIBO and prolonged OCTT. OCTT was not associated (p > 0.05) with intestinal complaints, BMI, anxiety or depression. Conclusions. About one third of IBS patients present pro longed OCTT, indicating delayed small bowel transit. This abnormality appears to be a predisposing condition for the development of SIBO. SIBO is more frequent in IBS patients with diarrhea. 2016 artículo científico 2469-1119 https://www.redalyc.org/articulo.oa?id=199349172004 en http://www.redalyc.org/revista.oa?id=1993 Acta Gastroenterológica Latinoamericana application/pdf Sociedad Argentina de Gastroenterología Acta Gastroenterológica Latinoamericana (Argentina) Num.4 Vol.46 |
| title | Prolonged orocecal transit time is associated with small intestinal bacterial overgrowth in irritable bowel syndrome in a tertiary referral hospital in Brazil |
| topic | Medicina orocecal transit time Irritable bowel syndrome small intestinal bacterial overgrowth |
| url | https://www.redalyc.org/articulo.oa?id=199349172004 |