Predictive value of the number of symptoms during pH monitoring for the diagnosis of Gastroesophageal Reflux Disease
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| Format: | Artículo científico |
| Langue: | en |
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Sociedad Argentina de Gastroenterología
2019
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| _version_ | 1876469496723537920 |
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| author | Julia R Kalluf |
| author_facet | Julia R Kalluf |
| contents | Predictive value of the number of symptoms during pH monitoring for the diagnosis of Gastroesophageal Reflux Disease Julia R Kalluf Fernando A M Herbella Fernanda M Lafraia Francisco Schlottmann Marco G Patti Medicina Symptoms Hypervigilance DeMeester Score Esophageal pH monitoring Gastroesophageal reflux disease Symptoms have a low accuracy for the diagnosis of gastroesophageal reflux disease (GERD) compared to pH monitoring. The absence of GERD in patients with reflux symptoms can be explained by esophageal dysmotility, visceral hypersensitivity, hypervigilance and psychosocial characteristics. The number of symptoms experienced in 24 hours may represent some of these functional, sensorial and psychosocial characteristics. Aims. This study aims is to correlate the number of symptoms reported during 24-hour pH monitoring with the diagnosis of GERD. Methods. We studied 424 non-selected patients (58% females, median age 41 years, range 18-77) that underwent a pH monitoring for suspected GERD. Esophageal symptoms, extraesophageal symptoms, and no symptoms were reported in 199 (47%), 129 (30%), and 150 (35%) of the tests, respectively. Patients were grouped in GERD + and GERD - according to the DeMeester score. Symptom association was defined by the Symptom Index. Results. GERD + comprised 180 (44%) patients. Total number of symptoms, number of esophageal and extraesophageal symptoms, and symptom index were higher in patients GERD +. Symptoms and DeMeester score did not correlate for the total number of symptoms, esophageal symptoms, extraesophageal symptoms and symptom index. Conclusion. In conclusion, GERD + patients reported higher number of symptoms during pHmonitoring but the number of symptoms is not a good predictor for GERD presence or severity. 2019 artículo científico 2469-1119 https://www.redalyc.org/articulo.oa?id=199362054005 https://www.redalyc.org/journal/1993/199362054005/ https://www.redalyc.org/journal/1993/199362054005/html/ https://www.redalyc.org/journal/1993/199362054005/199362054005.epub https://www.redalyc.org/journal/1993/199362054005/movil en http://www.redalyc.org/revista.oa?id=1993 Acta Gastroenterológica Latinoamericana application/pdf Sociedad Argentina de Gastroenterología Acta Gastroenterológica Latinoamericana (Argentina) Num.4 Vol.49 |
| format | Artículo científico |
| id | redalyc_199362054005 |
| institution | Redalyc |
| language | en |
| publishDate | 2019 |
| publisher | Sociedad Argentina de Gastroenterología |
| spellingShingle | Predictive value of the number of symptoms during pH monitoring for the diagnosis of Gastroesophageal Reflux Disease Julia R Kalluf Medicina Symptoms Hypervigilance DeMeester Score Esophageal pH monitoring Gastroesophageal reflux disease Predictive value of the number of symptoms during pH monitoring for the diagnosis of Gastroesophageal Reflux Disease Julia R Kalluf Fernando A M Herbella Fernanda M Lafraia Francisco Schlottmann Marco G Patti Medicina Symptoms Hypervigilance DeMeester Score Esophageal pH monitoring Gastroesophageal reflux disease Symptoms have a low accuracy for the diagnosis of gastroesophageal reflux disease (GERD) compared to pH monitoring. The absence of GERD in patients with reflux symptoms can be explained by esophageal dysmotility, visceral hypersensitivity, hypervigilance and psychosocial characteristics. The number of symptoms experienced in 24 hours may represent some of these functional, sensorial and psychosocial characteristics. Aims. This study aims is to correlate the number of symptoms reported during 24-hour pH monitoring with the diagnosis of GERD. Methods. We studied 424 non-selected patients (58% females, median age 41 years, range 18-77) that underwent a pH monitoring for suspected GERD. Esophageal symptoms, extraesophageal symptoms, and no symptoms were reported in 199 (47%), 129 (30%), and 150 (35%) of the tests, respectively. Patients were grouped in GERD + and GERD - according to the DeMeester score. Symptom association was defined by the Symptom Index. Results. GERD + comprised 180 (44%) patients. Total number of symptoms, number of esophageal and extraesophageal symptoms, and symptom index were higher in patients GERD +. Symptoms and DeMeester score did not correlate for the total number of symptoms, esophageal symptoms, extraesophageal symptoms and symptom index. Conclusion. In conclusion, GERD + patients reported higher number of symptoms during pHmonitoring but the number of symptoms is not a good predictor for GERD presence or severity. 2019 artículo científico 2469-1119 https://www.redalyc.org/articulo.oa?id=199362054005 https://www.redalyc.org/journal/1993/199362054005/ https://www.redalyc.org/journal/1993/199362054005/html/ https://www.redalyc.org/journal/1993/199362054005/199362054005.epub https://www.redalyc.org/journal/1993/199362054005/movil en http://www.redalyc.org/revista.oa?id=1993 Acta Gastroenterológica Latinoamericana application/pdf Sociedad Argentina de Gastroenterología Acta Gastroenterológica Latinoamericana (Argentina) Num.4 Vol.49 |
| title | Predictive value of the number of symptoms during pH monitoring for the diagnosis of Gastroesophageal Reflux Disease |
| topic | Medicina Symptoms Hypervigilance DeMeester Score Esophageal pH monitoring Gastroesophageal reflux disease |
| url | https://www.redalyc.org/articulo.oa?id=199362054005 https://www.redalyc.org/journal/1993/199362054005/ https://www.redalyc.org/journal/1993/199362054005/html/ https://www.redalyc.org/journal/1993/199362054005/199362054005.epub https://www.redalyc.org/journal/1993/199362054005/movil |