Antibiotic susceptibility in Helicobacter pylori strains isolated from Venezuelan patients with duodenal ulcer

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Main Author: María Eugenia Cavazza
Format: Artículo científico
Language:en
Published: Sociedad Venezolana de Microbiología 2017
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author María Eugenia Cavazza
author_facet María Eugenia Cavazza
contents Antibiotic susceptibility in Helicobacter pylori strains isolated from Venezuelan patients with duodenal ulcer María Eugenia Cavazza María Isabel Urrestarazu Noris Serrano Diana Ortiz-Princz Biología test resistance antibiotics Helicobacter pylori Helicobacter pylori antimicrobial drug resistance has appeared as an important cause of treatment failure. Samples were collected from 38 H. pylori infected patients with duodenal ulcers from the Gastroenterology Service of the “Hospital Vargas”, Caracas, Venezuela (2009-2011) and were processed by the E-test method. The 94.8% isolates were sensitive to clarithromycin and erythromycin with MIC values of <0.5 mg/L and < 2 mg/L respectively. The 92.2% of the strains had a tetracycline MIC under 1 mg/L and 37% of the sensitive H. pylori strains had a metronidazole MIC of <8 mg/L. Metronidazole resistance occurred in 24/38 strains (63.1%), while resistance to erythromycin was found in 2/38 strains (5.2%), clarithromycin in 2/38 (5.2%), and tetracycline in 3/38 (7.8%) of the isolates. None of the strains was found to be resistant to amoxicillin. We observed 6/38 (15.8%) multi-drug resistance of H. pylori isolates in different combinations. 2017 otro 1317-973X https://www.redalyc.org/articulo.oa?id=199454946009 en http://www.redalyc.org/revista.oa?id=1994 Revista de la Sociedad Venezolana de Microbiología application/pdf Sociedad Venezolana de Microbiología Revista de la Sociedad Venezolana de Microbiología (República Bolivariana de Venezuela) Num.2 Vol.37
format Artículo científico
id redalyc_199454946009
institution Redalyc
language en
publishDate 2017
publisher Sociedad Venezolana de Microbiología
spellingShingle Antibiotic susceptibility in Helicobacter pylori strains isolated from Venezuelan patients with duodenal ulcer
María Eugenia Cavazza
Biología
test
resistance
antibiotics
Helicobacter pylori
Antibiotic susceptibility in Helicobacter pylori strains isolated from Venezuelan patients with duodenal ulcer María Eugenia Cavazza María Isabel Urrestarazu Noris Serrano Diana Ortiz-Princz Biología test resistance antibiotics Helicobacter pylori Helicobacter pylori antimicrobial drug resistance has appeared as an important cause of treatment failure. Samples were collected from 38 H. pylori infected patients with duodenal ulcers from the Gastroenterology Service of the “Hospital Vargas”, Caracas, Venezuela (2009-2011) and were processed by the E-test method. The 94.8% isolates were sensitive to clarithromycin and erythromycin with MIC values of <0.5 mg/L and < 2 mg/L respectively. The 92.2% of the strains had a tetracycline MIC under 1 mg/L and 37% of the sensitive H. pylori strains had a metronidazole MIC of <8 mg/L. Metronidazole resistance occurred in 24/38 strains (63.1%), while resistance to erythromycin was found in 2/38 strains (5.2%), clarithromycin in 2/38 (5.2%), and tetracycline in 3/38 (7.8%) of the isolates. None of the strains was found to be resistant to amoxicillin. We observed 6/38 (15.8%) multi-drug resistance of H. pylori isolates in different combinations. 2017 otro 1317-973X https://www.redalyc.org/articulo.oa?id=199454946009 en http://www.redalyc.org/revista.oa?id=1994 Revista de la Sociedad Venezolana de Microbiología application/pdf Sociedad Venezolana de Microbiología Revista de la Sociedad Venezolana de Microbiología (República Bolivariana de Venezuela) Num.2 Vol.37
title Antibiotic susceptibility in Helicobacter pylori strains isolated from Venezuelan patients with duodenal ulcer
topic Biología
test
resistance
antibiotics
Helicobacter pylori
url https://www.redalyc.org/articulo.oa?id=199454946009