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| Format: | Artículo científico |
| Language: | en |
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Instituto Finlay
2010
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| Online Access: | https://www.redalyc.org/articulo.oa?id=203415359002 |
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Table of Contents:
- Invasive Meningococcal Disease. Cuba, 1983 - 2006 Antonio E. Pérez Félix Dickinson Rafael Llanes Salud Epidemiology Risk factors Immunization Neisseria meningitidis Invasive Meningococcal Disease Invasive Meningococcal Disease (IMD) is a worldwide health problem. In Cuba, vaccination against meningococcal B-C has been carried out since 1989. The study aimed at describing the epidemiology of IMD in Cuba from 1983 to 2006 and at contributing to the immunization strategy. A descriptive and analytical study was carried out. Epidemiological data was obtained from the National Surveillance System at the Institute "Pedro Kourí". More than 1 000 cases were reported in 1986 and the overall incidence was above 10/100 000 inhabitants. Since 1989 a remarkable and continuous decline in the incidence was observed. In the last nine years a strong association of IMD to boarding school students (OR=9.4; confidence interval 95%: 5.1-17.4), recluses (OR=5.9; CI 95%: 1.5 -24.3) and day students (OR=3.9; CI 95%: 2.8-5.6) was observed. Housewife (OR=4.9; CI 95%: 1.9-12.4) and pensioned (OR=4.5; CI 95%: 1.2-16.8) showed association with mortality. Previous vaccination was a protective factor against morbidity (OR=0.6; CI 95%: 0.4-1.0) and mortality (OR=0.4; CI 95%: 0.2-0.9) by IMD. Neisseriameningitidis B4:P1.15 was the main circulating strain. Incidence of IMD declined markedly in Cuba by using group BC strain-specific meningococcal vaccine. 2010 artículo científico 1025-0298 https://www.redalyc.org/articulo.oa?id=203415359002 en http://www.redalyc.org/revista.oa?id=2034 VacciMonitor application/pdf Instituto Finlay VacciMonitor (Cuba) Num.3 Vol.19