Preliminary comparisons between in vivo ultrasonographic virtual histology and histopathological findings of endarterectomized carotid plaque
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| Natura: | Artículo científico |
| Lingua: | en |
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Sociedade Brasileira de Angiologia e de Cirurgia Vascular
2013
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| author | Fábio Hüsemann Menezes |
| author_facet | Fábio Hüsemann Menezes |
| contents | Preliminary comparisons between in vivo ultrasonographic virtual histology and histopathological findings of endarterectomized carotid plaque Fábio Hüsemann Menezes Thiago do Carmo Silveira Sandra Aparecida Ferreira Silveira Sérgio Xavier Salles-Cunha Konradin Metze Ana Silvia Carvalho de Menezes Medicina carotid histology ultrasound Atherosclerosis Background: Extracranial carotid artery atherosclerosis is a major preventable cause of strokes, the second most common cause of death in developed countries. The degree of arterial lumen stenosis is the basis for surgical indications, but does not provide information about other plaque aspects. Studies in the literature suggest that the morphological characteristics of the plaque and its composition should also be included in the assessment of this disease. Objective: Investigate the correlation between atherosclerotic plaque composition defined by computer-assisted analysis of ultrasound images (virtual histology - USVH) and conventional histology. Method: The images of twelve plaques, obtained during preoperative ultrasound scanning, were analyzed by computer, and the grey scale images were correlated with the plaque components and subsequently compared with the histological findings of the analysis of the endarterectomy specimens. Results: The amount of lipids and fibromuscular tissue were strongly correlated in the two tests (R=0.83 and 0.91). There were no significant correlations with amount of blood or calcium (R=0.05 and 0.19). Conclusion: This study confirmed the usefulness of noninvasive USVH. Further technical improvements and software developments may promote the clinical application of this method. 2013 artículo científico 1677-5449 https://www.redalyc.org/articulo.oa?id=245029243003 en http://www.redalyc.org/revista.oa?id=2450 Jornal Vascular Brasileiro application/pdf Sociedade Brasileira de Angiologia e de Cirurgia Vascular Jornal Vascular Brasileiro (Brasil) Num.3 Vol.12 |
| format | Artículo científico |
| id | redalyc_245029243003 |
| institution | Redalyc |
| language | en |
| publishDate | 2013 |
| publisher | Sociedade Brasileira de Angiologia e de Cirurgia Vascular |
| spellingShingle | Preliminary comparisons between in vivo ultrasonographic virtual histology and histopathological findings of endarterectomized carotid plaque Fábio Hüsemann Menezes Medicina carotid histology ultrasound Atherosclerosis Preliminary comparisons between in vivo ultrasonographic virtual histology and histopathological findings of endarterectomized carotid plaque Fábio Hüsemann Menezes Thiago do Carmo Silveira Sandra Aparecida Ferreira Silveira Sérgio Xavier Salles-Cunha Konradin Metze Ana Silvia Carvalho de Menezes Medicina carotid histology ultrasound Atherosclerosis Background: Extracranial carotid artery atherosclerosis is a major preventable cause of strokes, the second most common cause of death in developed countries. The degree of arterial lumen stenosis is the basis for surgical indications, but does not provide information about other plaque aspects. Studies in the literature suggest that the morphological characteristics of the plaque and its composition should also be included in the assessment of this disease. Objective: Investigate the correlation between atherosclerotic plaque composition defined by computer-assisted analysis of ultrasound images (virtual histology - USVH) and conventional histology. Method: The images of twelve plaques, obtained during preoperative ultrasound scanning, were analyzed by computer, and the grey scale images were correlated with the plaque components and subsequently compared with the histological findings of the analysis of the endarterectomy specimens. Results: The amount of lipids and fibromuscular tissue were strongly correlated in the two tests (R=0.83 and 0.91). There were no significant correlations with amount of blood or calcium (R=0.05 and 0.19). Conclusion: This study confirmed the usefulness of noninvasive USVH. Further technical improvements and software developments may promote the clinical application of this method. 2013 artículo científico 1677-5449 https://www.redalyc.org/articulo.oa?id=245029243003 en http://www.redalyc.org/revista.oa?id=2450 Jornal Vascular Brasileiro application/pdf Sociedade Brasileira de Angiologia e de Cirurgia Vascular Jornal Vascular Brasileiro (Brasil) Num.3 Vol.12 |
| title | Preliminary comparisons between in vivo ultrasonographic virtual histology and histopathological findings of endarterectomized carotid plaque |
| topic | Medicina carotid histology ultrasound Atherosclerosis |
| url | https://www.redalyc.org/articulo.oa?id=245029243003 |