Comparative study of the Ankle-Brachial Index in diabetic and non-diabetic patients with critical limb ischemia

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Autor principal: Vanessa Prado dos Santos
Formato: Artículo científico
Lenguaje:en
Publicado: Sociedade Brasileira de Angiologia e de Cirurgia Vascular 2015
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author Vanessa Prado dos Santos
author_facet Vanessa Prado dos Santos
contents Comparative study of the Ankle-Brachial Index in diabetic and non-diabetic patients with critical limb ischemia Vanessa Prado dos Santos Carlos Alberto Silveira Alves Ronald José Ribeiro Fidelis Cícero Fidelis José Siqueira de Araújo Filho Medicina Ankle Ankle Ankle Ankle Ankle Background: Calcification of the arterial tunica media can falsely elevate the Ankle-Brachial Index (ABI) in diabetics, making it difficult to assess arterial disease. Objective: To compare ABI values in diabetics and non-diabetics with critical ischemia. Methods: A total of 140 patients (60% diabetics) with critical ischemia due to infrainguinal peripheral arterial obstructive disease were recruited from the vascular surgery service at the Complexo Hospitalar Universitário Professor Edgard Santos. Mean ABI values for the two groups of patients were compared and correlated with severity of ischemia, according to the Rutherford Classification. Statistical analysis was conducted using EPI-INFO. Results: A majority of the 140 patients (77%) were classified as Rutherford Category 5, 6% as Category 4 and 17% as Category 6. Nine diabetics (11%) and one non-diabetic (2%) exhibited ABI > 1.15 (p = 0.02) and were excluded from the comparative analysis of mean ABIs. For the 130-patient sample, the 75 diabetic patients had a mean ABI for the posterior tibial artery of 0.26, vs. 0.28 for the 55 non-diabetic patients (p = 0.6); while mean ABIs for the dorsalis pedis artery were 0.32 vs. 0.23 respectively (p = 0.06). When the patients were stratified by Rutherford categories, there were no differences in mean ABIs in categories 4 or 5. Only mean ABI for the dorsalis pedis artery in Category 6 patients was significantly higher among diabetics (0.44 vs. 0.16; p = 0.03). Conclusions: The diabetic patients had a higher prevalence of falsely elevated ABI, but when these cases were excluded, mean ABI values were similar to those of non-diabetic patients, with the exception of ABI measured at the dorsalis pedis artery in patients with category 6 ischemia. 2015 artículo científico 1677-5449 https://www.redalyc.org/articulo.oa?id=245042938005 en http://www.redalyc.org/revista.oa?id=2450 Jornal Vascular Brasileiro application/pdf Sociedade Brasileira de Angiologia e de Cirurgia Vascular Jornal Vascular Brasileiro (Brasil) Num.4 Vol.14
format Artículo científico
id redalyc_245042938005
institution Redalyc
language en
publishDate 2015
publisher Sociedade Brasileira de Angiologia e de Cirurgia Vascular
spellingShingle Comparative study of the Ankle-Brachial Index in diabetic and non-diabetic patients with critical limb ischemia
Vanessa Prado dos Santos
Medicina
Ankle
Ankle
Ankle
Ankle
Ankle
Comparative study of the Ankle-Brachial Index in diabetic and non-diabetic patients with critical limb ischemia Vanessa Prado dos Santos Carlos Alberto Silveira Alves Ronald José Ribeiro Fidelis Cícero Fidelis José Siqueira de Araújo Filho Medicina Ankle Ankle Ankle Ankle Ankle Background: Calcification of the arterial tunica media can falsely elevate the Ankle-Brachial Index (ABI) in diabetics, making it difficult to assess arterial disease. Objective: To compare ABI values in diabetics and non-diabetics with critical ischemia. Methods: A total of 140 patients (60% diabetics) with critical ischemia due to infrainguinal peripheral arterial obstructive disease were recruited from the vascular surgery service at the Complexo Hospitalar Universitário Professor Edgard Santos. Mean ABI values for the two groups of patients were compared and correlated with severity of ischemia, according to the Rutherford Classification. Statistical analysis was conducted using EPI-INFO. Results: A majority of the 140 patients (77%) were classified as Rutherford Category 5, 6% as Category 4 and 17% as Category 6. Nine diabetics (11%) and one non-diabetic (2%) exhibited ABI > 1.15 (p = 0.02) and were excluded from the comparative analysis of mean ABIs. For the 130-patient sample, the 75 diabetic patients had a mean ABI for the posterior tibial artery of 0.26, vs. 0.28 for the 55 non-diabetic patients (p = 0.6); while mean ABIs for the dorsalis pedis artery were 0.32 vs. 0.23 respectively (p = 0.06). When the patients were stratified by Rutherford categories, there were no differences in mean ABIs in categories 4 or 5. Only mean ABI for the dorsalis pedis artery in Category 6 patients was significantly higher among diabetics (0.44 vs. 0.16; p = 0.03). Conclusions: The diabetic patients had a higher prevalence of falsely elevated ABI, but when these cases were excluded, mean ABI values were similar to those of non-diabetic patients, with the exception of ABI measured at the dorsalis pedis artery in patients with category 6 ischemia. 2015 artículo científico 1677-5449 https://www.redalyc.org/articulo.oa?id=245042938005 en http://www.redalyc.org/revista.oa?id=2450 Jornal Vascular Brasileiro application/pdf Sociedade Brasileira de Angiologia e de Cirurgia Vascular Jornal Vascular Brasileiro (Brasil) Num.4 Vol.14
title Comparative study of the Ankle-Brachial Index in diabetic and non-diabetic patients with critical limb ischemia
topic Medicina
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url https://www.redalyc.org/articulo.oa?id=245042938005