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Main Author: ANÍBAL NIETO
Format: Artículo científico
Language:en
Published: Universidad del Valle 2009
Subjects:
Online Access:https://www.redalyc.org/articulo.oa?id=28340206
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author ANÍBAL NIETO
author_facet ANÍBAL NIETO
contents Association between calcium intake, parathormone levels and blood pressure during pregnancy ANÍBAL NIETO JULIÁN A. HERRERA JOSÉ VILLAR ROBERTO MATORRAS CARLOS LÓPEZ DE LA MANZANARA IGNACIO ARRIBAS JULIA ÁLVAREZ EUGENIA PEIRÓ Medicina PTH: PTH Endothelin Nitric oxide Calcium intake rp: Preeclampsia Purpose: To evaluate the association between calcium intake from diet, calciotropic hormones (PTH, PTH-rp), vasoactive regulators (endothelin, nitric oxide) and blood pressure levels during pregnancy, birth and puerperium.Method: In a prospective study 149 healthy normotensive primigravidas were followed-up from 15 weeks of gestation to puerperium. Daily calcium intake, calciuria, PTH, PTH-rp, endothelin, nitrite-nitrate, and Holter Test were assessed. Linear regression models were performed to evaluate the association between calcium intake, blood pressure levels and the laboratory tests. Multivariate regression models were performed to control potential confounders.Results: A significant increase of calcium intake during pregnancy was observed (931±301 mg/day to 1,195±467 mg/day, p<0.001). Plasma PTH-rp, endothelin, and nitrite-nitrate levels did not change during pregnancy. Among the women 38 (25.4%) had low calcium intake (<800 mg/day) with a larger increase of systolic and diastolic blood pressure during pregnancy (p=0.04) birth (p=0.006) and puerperium (p=0.01). After adjusting for other factors the multivariate analyses showed statistical association between low calcium intake, high parathormone levels and high systolic blood pressure levels during pregnancy p=0.002).Conclusion: Low calcium intake during pregnancy is associated with a larger increase of systolic blood pressure and highparathormone levels. 2009 artículo científico 0120-8322 https://www.redalyc.org/articulo.oa?id=28340206 en http://www.redalyc.org/revista.oa?id=283 Colombia Médica application/pdf Universidad del Valle Colombia Médica (Colombia) Num.2 Vol.40
format Artículo científico
id redalyc_28340206
language en
publishDate 2009
publisher Universidad del Valle
spellingShingle Association between calcium intake, parathormone levels and blood pressure during pregnancy
ANÍBAL NIETO
Medicina
PTH: PTH
Endothelin
Nitric oxide
Calcium intake
rp: Preeclampsia
Association between calcium intake, parathormone levels and blood pressure during pregnancy ANÍBAL NIETO JULIÁN A. HERRERA JOSÉ VILLAR ROBERTO MATORRAS CARLOS LÓPEZ DE LA MANZANARA IGNACIO ARRIBAS JULIA ÁLVAREZ EUGENIA PEIRÓ Medicina PTH: PTH Endothelin Nitric oxide Calcium intake rp: Preeclampsia Purpose: To evaluate the association between calcium intake from diet, calciotropic hormones (PTH, PTH-rp), vasoactive regulators (endothelin, nitric oxide) and blood pressure levels during pregnancy, birth and puerperium.Method: In a prospective study 149 healthy normotensive primigravidas were followed-up from 15 weeks of gestation to puerperium. Daily calcium intake, calciuria, PTH, PTH-rp, endothelin, nitrite-nitrate, and Holter Test were assessed. Linear regression models were performed to evaluate the association between calcium intake, blood pressure levels and the laboratory tests. Multivariate regression models were performed to control potential confounders.Results: A significant increase of calcium intake during pregnancy was observed (931±301 mg/day to 1,195±467 mg/day, p<0.001). Plasma PTH-rp, endothelin, and nitrite-nitrate levels did not change during pregnancy. Among the women 38 (25.4%) had low calcium intake (<800 mg/day) with a larger increase of systolic and diastolic blood pressure during pregnancy (p=0.04) birth (p=0.006) and puerperium (p=0.01). After adjusting for other factors the multivariate analyses showed statistical association between low calcium intake, high parathormone levels and high systolic blood pressure levels during pregnancy p=0.002).Conclusion: Low calcium intake during pregnancy is associated with a larger increase of systolic blood pressure and highparathormone levels. 2009 artículo científico 0120-8322 https://www.redalyc.org/articulo.oa?id=28340206 en http://www.redalyc.org/revista.oa?id=283 Colombia Médica application/pdf Universidad del Valle Colombia Médica (Colombia) Num.2 Vol.40
title Association between calcium intake, parathormone levels and blood pressure during pregnancy
topic Medicina
PTH: PTH
Endothelin
Nitric oxide
Calcium intake
rp: Preeclampsia
url https://www.redalyc.org/articulo.oa?id=28340206