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| Formato: | Artículo científico |
| Lenguaje: | en |
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Universidad del Valle
2015
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| Acceso en línea: | https://www.redalyc.org/articulo.oa?id=28343295003 https://www.redalyc.org/journal/283/28343295003/ https://www.redalyc.org/journal/283/28343295003/html/ https://www.redalyc.org/journal/283/28343295003/28343295003.epub https://www.redalyc.org/journal/283/28343295003/movil |
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| _version_ | 1866556614940557312 |
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| author | Liliana Arias Urueña |
| author_facet | Liliana Arias Urueña |
| contents | Clinical aspects associated with syndromic forms of Orofacial Clefts in a Colombian population Liliana Arias Urueña Ignacio Briceño Balcazar Julio Martinez Lozano Andrew Collins Daniel Alfredo Uricoechea Patiño Medicina pre pre pre aarskog aarskog Objectives: To present descriptive epidemiology of Orofacial Clefts and to determine the association of syndromic forms with antenatal high-risk conditions, preterm birth, and comorbidities among nested-series of cases. Methods: A study of nested-series of cases was conducted. Frequencies of cleft type, associated congenital anomalies, syndromic, non-syndromic and multiple malformation forms, and distribution of Orofacial Clefts according to sex and affected-side were determined. Odds ratios were calculated as measures of association between syndromic forms and antenatal high-risk conditions, preterm birth and comorbidities. A total of three hundred and eleven patients with Orofacial Clefts were assessed in a 12-month period.Results: The most frequent type of Orofacial Clefts was cleft lip and palate, this type of cleft was more frequent in males, whereas cleft palate occurred more often in females. The most common cases occurred as non-syndromic forms. Aarskog-Scott syndrome showed the highest frequency amongst syndromic forms. Hypertensive disorders in pregnancy, developmental dysplasia of the hip, central nervous diseases and respiratory failure showed significant statistical associations (p <0.05) with syndromic forms.Conclusions: These data provide an epidemiological reference of Orofacial Clefts in Colombia. Novel associations between syndromic forms and clinical variables are determined. In order to investigate causality relationships between these variables further studies must be carried out. 2015 artículo científico 0120-8322 https://www.redalyc.org/articulo.oa?id=28343295003 https://www.redalyc.org/journal/283/28343295003/ https://www.redalyc.org/journal/283/28343295003/html/ https://www.redalyc.org/journal/283/28343295003/28343295003.epub https://www.redalyc.org/journal/283/28343295003/movil en http://www.redalyc.org/revista.oa?id=283 Colombia Médica application/pdf Universidad del Valle Colombia Médica (Colombia) Num.4 Vol.46 |
| format | Artículo científico |
| id | redalyc_28343295003 |
| language | en |
| publishDate | 2015 |
| publisher | Universidad del Valle |
| spellingShingle | Clinical aspects associated with syndromic forms of Orofacial Clefts in a Colombian population Liliana Arias Urueña Medicina pre pre pre aarskog aarskog Clinical aspects associated with syndromic forms of Orofacial Clefts in a Colombian population Liliana Arias Urueña Ignacio Briceño Balcazar Julio Martinez Lozano Andrew Collins Daniel Alfredo Uricoechea Patiño Medicina pre pre pre aarskog aarskog Objectives: To present descriptive epidemiology of Orofacial Clefts and to determine the association of syndromic forms with antenatal high-risk conditions, preterm birth, and comorbidities among nested-series of cases. Methods: A study of nested-series of cases was conducted. Frequencies of cleft type, associated congenital anomalies, syndromic, non-syndromic and multiple malformation forms, and distribution of Orofacial Clefts according to sex and affected-side were determined. Odds ratios were calculated as measures of association between syndromic forms and antenatal high-risk conditions, preterm birth and comorbidities. A total of three hundred and eleven patients with Orofacial Clefts were assessed in a 12-month period.Results: The most frequent type of Orofacial Clefts was cleft lip and palate, this type of cleft was more frequent in males, whereas cleft palate occurred more often in females. The most common cases occurred as non-syndromic forms. Aarskog-Scott syndrome showed the highest frequency amongst syndromic forms. Hypertensive disorders in pregnancy, developmental dysplasia of the hip, central nervous diseases and respiratory failure showed significant statistical associations (p <0.05) with syndromic forms.Conclusions: These data provide an epidemiological reference of Orofacial Clefts in Colombia. Novel associations between syndromic forms and clinical variables are determined. In order to investigate causality relationships between these variables further studies must be carried out. 2015 artículo científico 0120-8322 https://www.redalyc.org/articulo.oa?id=28343295003 https://www.redalyc.org/journal/283/28343295003/ https://www.redalyc.org/journal/283/28343295003/html/ https://www.redalyc.org/journal/283/28343295003/28343295003.epub https://www.redalyc.org/journal/283/28343295003/movil en http://www.redalyc.org/revista.oa?id=283 Colombia Médica application/pdf Universidad del Valle Colombia Médica (Colombia) Num.4 Vol.46 |
| title | Clinical aspects associated with syndromic forms of Orofacial Clefts in a Colombian population |
| topic | Medicina pre pre pre aarskog aarskog |
| url | https://www.redalyc.org/articulo.oa?id=28343295003 https://www.redalyc.org/journal/283/28343295003/ https://www.redalyc.org/journal/283/28343295003/html/ https://www.redalyc.org/journal/283/28343295003/28343295003.epub https://www.redalyc.org/journal/283/28343295003/movil |