Whole blood for blood loss: hemostatic resuscitation in damage control
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Redalyc
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Universidad del Valle
2020
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| _version_ | 1876489477913837568 |
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| author | Juan Carlos Salamea-Molina |
| author_facet | Juan Carlos Salamea-Molina |
| contents | Whole blood for blood loss: hemostatic resuscitation in damage control Juan Carlos Salamea-Molina Amber Nicole Himmler Laura Isabel Valencia-Angel Carlos A. Ordoñez Michael W. Parra Yaset Caicedo Mónica Guzmán-Rodríguez Claudia Orlas Marcela Granados Carmenza Macia Alberto García José Julián Serna Marisol Badiel Juan Carlos Puyana Medicina shock hemorrhagic hemostatics hypothermia blood safety Hemorrhagic shock and its complications are a major cause of death among trauma patients. The management of hemorrhagic shock using a damage control resuscitation strategy has been shown to decrease mortality and improve patient outcomes. One of the components of damage control resuscitation is hemostatic resuscitation, which involves the replacement of lost blood volume with components such as packed red blood cells, fresh frozen plasma, cryoprecipitate, and platelets in a 1:1:1:1 ratio. However, this is a strategy that is not applicable in many parts of Latin America and other low-and-middle-income countries throughout the world, where there is a lack of well-equipped blood banks and an insufficient availability of blood products. To overcome these barriers, we propose the use of cold fresh whole blood for hemostatic resuscitation in exsanguinating patients. Over 6 years of experience in Ecuador has shown that resuscitation with cold fresh whole blood has similar outcomes and a similar safety profile compared to resuscitation with hemocomponents. Whole blood confers many advantages over component therapy including, but not limited to the transfusion of blood with a physiologic ratio of components, ease of transport and transfusion, less volume of anticoagulants and additives transfused to the patient, and exposure to fewer donors. Whole blood is a tool with reemerging potential that can be implemented in civilian trauma centers with optimal results and less technical demand. 2020 artículo científico 0120-8322 https://www.redalyc.org/articulo.oa?id=28366176005 https://www.redalyc.org/journal/283/28366176005/ https://www.redalyc.org/journal/283/28366176005/html/ https://www.redalyc.org/journal/283/28366176005/28366176005.epub https://www.redalyc.org/journal/283/28366176005/movil 10.25100/cm.v51i4.4511 en http://www.redalyc.org/revista.oa?id=283 Colombia Médica application/pdf Universidad del Valle Colombia Médica (Colombia) Num.4 Vol.51 |
| format | Artículo científico |
| id | redalyc_28366176005 |
| institution | Redalyc |
| language | en |
| publishDate | 2020 |
| publisher | Universidad del Valle |
| spellingShingle | Whole blood for blood loss: hemostatic resuscitation in damage control Juan Carlos Salamea-Molina Medicina shock hemorrhagic hemostatics hypothermia blood safety Whole blood for blood loss: hemostatic resuscitation in damage control Juan Carlos Salamea-Molina Amber Nicole Himmler Laura Isabel Valencia-Angel Carlos A. Ordoñez Michael W. Parra Yaset Caicedo Mónica Guzmán-Rodríguez Claudia Orlas Marcela Granados Carmenza Macia Alberto García José Julián Serna Marisol Badiel Juan Carlos Puyana Medicina shock hemorrhagic hemostatics hypothermia blood safety Hemorrhagic shock and its complications are a major cause of death among trauma patients. The management of hemorrhagic shock using a damage control resuscitation strategy has been shown to decrease mortality and improve patient outcomes. One of the components of damage control resuscitation is hemostatic resuscitation, which involves the replacement of lost blood volume with components such as packed red blood cells, fresh frozen plasma, cryoprecipitate, and platelets in a 1:1:1:1 ratio. However, this is a strategy that is not applicable in many parts of Latin America and other low-and-middle-income countries throughout the world, where there is a lack of well-equipped blood banks and an insufficient availability of blood products. To overcome these barriers, we propose the use of cold fresh whole blood for hemostatic resuscitation in exsanguinating patients. Over 6 years of experience in Ecuador has shown that resuscitation with cold fresh whole blood has similar outcomes and a similar safety profile compared to resuscitation with hemocomponents. Whole blood confers many advantages over component therapy including, but not limited to the transfusion of blood with a physiologic ratio of components, ease of transport and transfusion, less volume of anticoagulants and additives transfused to the patient, and exposure to fewer donors. Whole blood is a tool with reemerging potential that can be implemented in civilian trauma centers with optimal results and less technical demand. 2020 artículo científico 0120-8322 https://www.redalyc.org/articulo.oa?id=28366176005 https://www.redalyc.org/journal/283/28366176005/ https://www.redalyc.org/journal/283/28366176005/html/ https://www.redalyc.org/journal/283/28366176005/28366176005.epub https://www.redalyc.org/journal/283/28366176005/movil 10.25100/cm.v51i4.4511 en http://www.redalyc.org/revista.oa?id=283 Colombia Médica application/pdf Universidad del Valle Colombia Médica (Colombia) Num.4 Vol.51 |
| title | Whole blood for blood loss: hemostatic resuscitation in damage control |
| topic | Medicina shock hemorrhagic hemostatics hypothermia blood safety |
| url | https://www.redalyc.org/articulo.oa?id=28366176005 https://www.redalyc.org/journal/283/28366176005/ https://www.redalyc.org/journal/283/28366176005/html/ https://www.redalyc.org/journal/283/28366176005/28366176005.epub https://www.redalyc.org/journal/283/28366176005/movil |