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| Format: | Artículo científico |
| Language: | en |
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Sociedad Argentina de Cardiología
2014
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| Online Access: | https://www.redalyc.org/articulo.oa?id=305332235005 |
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Table of Contents:
- Clinical Profile of Patients with Hypertrophic Cardiomyopathy at a University Hospital Aníbal M. Arias Rodrigo P. Bagnati Diego Pérez De Arenaza Pablo F. Oberti Mariano L. Falconi Rodolfo Pizarro Gonzalo Díaz Babio Luciano O. Lucas Ricardo García Mónaco César A. Belziti Medicina Key words Diagnosis Treatment Prognosis Hypertrophic cardiomyopathy Introduction: Hypertrophic cardiomyopathy is the most frequent genetic cardiomyopathy and there is no available information on base - line characteristics and outcome of patients with this disease in our country. o bjective: To know the clinical profile of patients with hypertrophic cardiomyopathy and to identify predictors of adverse outcome. Methods: One hundred- and forty three patients with hypertrophic cardiomyopathy at the Hospital Italiano of Buenos Aires between 2005 and 2011were included in the study. r esults: Median age was 66 years and 52 % were women. Most patients presented an asymmetric distribution (92%) and 60 % had dynamic obstruction. Mortality was 5.59 % at a median follow-up of 2.11-years [25-75 IQR (0.75- 3.70)]. The most prevalent symptom was dyspnea (36%), followed by angina (17%) and syncope (14%). Dynamic obstruction, moderate or severe mitral regurgitation, left atrial diameter and female gender were independently associa ted with dyspnea. Dynamic obstruction was independently associated with angina. Maximum wall thickness was directly and independently associ - ated with syncope, while ejection fraction and left ventricular hypertrophy or negative T in the electrocardiogram presented an inverse relationship. Mortality was independently associated with hospitalization for decompensated heart failure. Conclusion: Similar to previous studies, our population shows that hypertrophic cardiomyopathy is a heterogeneous disease. A prospective study is necessary to validate the risk predictors assessed in this study. 2014 artículo científico 0034-7000 https://www.redalyc.org/articulo.oa?id=305332235005 en http://www.redalyc.org/revista.oa?id=3053 Revista Argentina de Cardiología application/pdf Sociedad Argentina de Cardiología Revista Argentina de Cardiología (Argentina) Num.5 Vol.82