Heart Transplantation Using Donors after Circulatory Death: From Research to Clinical Practice
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Redalyc
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| Natura: | Artículo científico |
| Lingua: | en |
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Sociedad Argentina de Cardiología
2016
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| _version_ | 1876438350898921472 |
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| author | GUSTAVO KNOP |
| author_facet | GUSTAVO KNOP |
| contents | Heart Transplantation Using Donors after Circulatory Death: From Research to Clinical Practice GUSTAVO KNOP Medicina ment methods induced Tissue donor classification Donation after circulatory death for heart transplantation was abandoned in the 1970s with the advent of the brain death law (dona - tion after brain death), where the donor heart is beating and perfused up to the moment prior to organ retrieval. Shortage of donors has renewed the interest in animal and clinical research of donors after circulatory death for heart transplantation, aiming at opti - mizing heart function after the period of oxygen deprivation caused by severe hypotension and subsequent circulatory arrest. This study presents the initial experience with donation after circulatory death for heart transplantation at our institution. Papworth Hospital has performed a successful clinical investigation in which ten cardiac transplants were performed with hearts from dona - tion after circulatory death, without mortality. Low risk recipients who had previously signed their consent were chosen. Most hearts from donation after circulatory death were reperfused with an extracorporeal circulation device, and following weaning from the cir - culatory support the heart was harvested and connected to the perfusion machine for transportation and simultaneous assessment of function before implantation. In conclusion, this technique could be used for cardiac transplantation with satisfactory outcomes. 2016 artículo científico 0034-7000 https://www.redalyc.org/articulo.oa?id=305344777013 en http://www.redalyc.org/revista.oa?id=3053 Revista Argentina de Cardiología application/pdf Sociedad Argentina de Cardiología Revista Argentina de Cardiología (Argentina) Num.1 Vol.84 |
| format | Artículo científico |
| id | redalyc_305344777013 |
| institution | Redalyc |
| language | en |
| publishDate | 2016 |
| publisher | Sociedad Argentina de Cardiología |
| spellingShingle | Heart Transplantation Using Donors after Circulatory Death: From Research to Clinical Practice GUSTAVO KNOP Medicina ment methods induced Tissue donor classification Heart Transplantation Using Donors after Circulatory Death: From Research to Clinical Practice GUSTAVO KNOP Medicina ment methods induced Tissue donor classification Donation after circulatory death for heart transplantation was abandoned in the 1970s with the advent of the brain death law (dona - tion after brain death), where the donor heart is beating and perfused up to the moment prior to organ retrieval. Shortage of donors has renewed the interest in animal and clinical research of donors after circulatory death for heart transplantation, aiming at opti - mizing heart function after the period of oxygen deprivation caused by severe hypotension and subsequent circulatory arrest. This study presents the initial experience with donation after circulatory death for heart transplantation at our institution. Papworth Hospital has performed a successful clinical investigation in which ten cardiac transplants were performed with hearts from dona - tion after circulatory death, without mortality. Low risk recipients who had previously signed their consent were chosen. Most hearts from donation after circulatory death were reperfused with an extracorporeal circulation device, and following weaning from the cir - culatory support the heart was harvested and connected to the perfusion machine for transportation and simultaneous assessment of function before implantation. In conclusion, this technique could be used for cardiac transplantation with satisfactory outcomes. 2016 artículo científico 0034-7000 https://www.redalyc.org/articulo.oa?id=305344777013 en http://www.redalyc.org/revista.oa?id=3053 Revista Argentina de Cardiología application/pdf Sociedad Argentina de Cardiología Revista Argentina de Cardiología (Argentina) Num.1 Vol.84 |
| title | Heart Transplantation Using Donors after Circulatory Death: From Research to Clinical Practice |
| topic | Medicina ment methods induced Tissue donor classification |
| url | https://www.redalyc.org/articulo.oa?id=305344777013 |