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Autore principale: Leandro Freire dos Santos
Natura: Artículo científico
Lingua:en
Pubblicazione: Universidade Estadual de Maringá 2012
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Accesso online:https://www.redalyc.org/articulo.oa?id=307226631010
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Sommario:
  • Levan in the developing of new colon-specific polymer material: evaluation of the permeability, moisture and thermal analyses in free films of Eudragit® FS 30 D Leandro Freire dos Santos Edgardo Alfonso Gómez Pineda Fernando César Bazani Cabral de Melo Maria Antonia Pedrine Colabone Celligoi Osvaldo Albuquerque Cavalcanti Medicina colon Coating material thermal analysis specific release physicochemical characterization Levan was used as agent in the synthesis of new colon-specific polymeric matrix together with Eudragit® FS 30 D. Eudragit® FS 30 D films incorporated with levan were made by casting process and characterized to: water vapour transmission, sweeling index, differential scanning calorimetry and thermogravimetric. The levan increased the films permeability (p < 0.001) however did not influenced in the sweeling index of the formulations (p > 0.05). The thermal analyses of the films indicated a glass transition temperature approximate at 47°C and thermal decomposition at 400°C. The results indicated that there is potential for using such site-specificity blend as pharmaceutical coating material. 2012 artículo científico 1679-9291 https://www.redalyc.org/articulo.oa?id=307226631010 en http://www.redalyc.org/revista.oa?id=3072 Acta Scientiarum. Health Sciences application/pdf Universidade Estadual de Maringá Acta Scientiarum. Health Sciences (Brasil) Num.2 Vol.34