Influence of B-Hydroxy-B-methylbutyrate on predominantly white and red muscles of rats not submitted to physical exercise

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Auteur principal: Mizael Pereira
Format: Artículo científico
Langue:en
Publié: Universidade Estadual de Maringá 2018
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author Mizael Pereira
author_facet Mizael Pereira
contents Influence of B-Hydroxy-B-methylbutyrate on predominantly white and red muscles of rats not submitted to physical exercise Mizael Pereira Letícia Rossi Daré Cleuber Rodrigo de Souza Bueno Idvaldo Aparecido Favaretto-Júnior Rogerio Leone Buchaim Jesus Carlos Andreo Medicina soleus Leucine supplementation skeletal muscle extensor digitorum longus This study evaluated the influence of β-hydroxy-β-methylbutyrate (HMB) on the body weight and morphometry of white and red muscle fibers of sedentary rats. 29 male rats were divided in: initial control group (ICG ) (n = 5), euthanized at study onset, and three treated groups (n = 8 each): placebo control group (PCG) received saline for 4 weeks; experimental group (EG) received 0.3 g kg-1 of HMB daily and controlled diet; and experimental group ad libitum, (EGA) received 0.3g kg-1 of HMB daily, without food restriction. There was no difference in food intake and body weight between treated groups. For the EDL muscle, treated groups were different from ICG. Concerning the soleus muscle, no treated group was different from each other and only the EGA presented difference compared to the ICG. Data also did not reveal correlation between the variables food intake and body weight. HMB did not change the body weight or morphometry of EDL muscle fibers. However, the HMB combined with ad libitum feeding was able to change the morphometry of soleus muscle fibers. 2018 artículo científico 1679-9291 https://www.redalyc.org/articulo.oa?id=307259135025 https://www.redalyc.org/journal/3072/307259135025/ https://www.redalyc.org/journal/3072/307259135025/html/ https://www.redalyc.org/journal/3072/307259135025/307259135025.epub https://www.redalyc.org/journal/3072/307259135025/movil https://doi.org/10.4025/actascihealthsci.v40i1.38270 en http://www.redalyc.org/revista.oa?id=3072 Acta Scientiarum. Health Sciences application/pdf Universidade Estadual de Maringá Acta Scientiarum. Health Sciences (Brasil) Vol.40
format Artículo científico
id redalyc_307259135025
institution Redalyc
language en
publishDate 2018
publisher Universidade Estadual de Maringá
spellingShingle Influence of B-Hydroxy-B-methylbutyrate on predominantly white and red muscles of rats not submitted to physical exercise
Mizael Pereira
Medicina
soleus
Leucine
supplementation
skeletal muscle
extensor digitorum longus
Influence of B-Hydroxy-B-methylbutyrate on predominantly white and red muscles of rats not submitted to physical exercise Mizael Pereira Letícia Rossi Daré Cleuber Rodrigo de Souza Bueno Idvaldo Aparecido Favaretto-Júnior Rogerio Leone Buchaim Jesus Carlos Andreo Medicina soleus Leucine supplementation skeletal muscle extensor digitorum longus This study evaluated the influence of β-hydroxy-β-methylbutyrate (HMB) on the body weight and morphometry of white and red muscle fibers of sedentary rats. 29 male rats were divided in: initial control group (ICG ) (n = 5), euthanized at study onset, and three treated groups (n = 8 each): placebo control group (PCG) received saline for 4 weeks; experimental group (EG) received 0.3 g kg-1 of HMB daily and controlled diet; and experimental group ad libitum, (EGA) received 0.3g kg-1 of HMB daily, without food restriction. There was no difference in food intake and body weight between treated groups. For the EDL muscle, treated groups were different from ICG. Concerning the soleus muscle, no treated group was different from each other and only the EGA presented difference compared to the ICG. Data also did not reveal correlation between the variables food intake and body weight. HMB did not change the body weight or morphometry of EDL muscle fibers. However, the HMB combined with ad libitum feeding was able to change the morphometry of soleus muscle fibers. 2018 artículo científico 1679-9291 https://www.redalyc.org/articulo.oa?id=307259135025 https://www.redalyc.org/journal/3072/307259135025/ https://www.redalyc.org/journal/3072/307259135025/html/ https://www.redalyc.org/journal/3072/307259135025/307259135025.epub https://www.redalyc.org/journal/3072/307259135025/movil https://doi.org/10.4025/actascihealthsci.v40i1.38270 en http://www.redalyc.org/revista.oa?id=3072 Acta Scientiarum. Health Sciences application/pdf Universidade Estadual de Maringá Acta Scientiarum. Health Sciences (Brasil) Vol.40
title Influence of B-Hydroxy-B-methylbutyrate on predominantly white and red muscles of rats not submitted to physical exercise
topic Medicina
soleus
Leucine
supplementation
skeletal muscle
extensor digitorum longus
url https://www.redalyc.org/articulo.oa?id=307259135025
https://www.redalyc.org/journal/3072/307259135025/
https://www.redalyc.org/journal/3072/307259135025/html/
https://www.redalyc.org/journal/3072/307259135025/307259135025.epub
https://www.redalyc.org/journal/3072/307259135025/movil
https://doi.org/10.4025/actascihealthsci.v40i1.38270