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| Format: | Artículo científico |
| Language: | en |
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Associação de Psiquiatria do Rio Grande do Sul
2014
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| Online Access: | https://www.redalyc.org/articulo.oa?id=311032220007 |
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| author | Guilherme Astor Torres |
| author_facet | Guilherme Astor Torres |
| contents | Profile of patients treated with malariotherapy in a psychiatric hospital in Porto Alegre, Brazil: a historical note Guilherme Astor Torres Maria Helena Itaqui Lopes Edson Medeiros Cheuiche Luiz Gustavo Guilhermano Psicología Wagner Jauregg Neurosyphilis malaria fever therapy Introduction: Malariotherapy was a treatment to cure neurosyphilis developed in 1917 by Wagner-Jauregg, by inoculating blood infected with malaria in patients with neurosyphilis. The patient had febrile episodes that often cured him of the syphilitic infection. This treatment won the Nobel Prize in Medicine in 1927 and it was introduced in Hospital Psiquiátrico São Pedro (HPSP) in 1929. Methods: This is a descriptive retrospective cross-sectional study with collection of historical secondary data. Data were collected from a sample of 19 medical records of patients treated with malariotherapy in HPSP, in 1929 and 1930. Results: Most patients were white men aged from 25 to 40 years. The mean length of hospital stay was 1.4 year and the outcomes at this early application of malariotherapy were mostly negative (63.2% died). Discussion: The 19 cases evaluated in this study refer to the first year of application of malariotherapy in HPSP. The statistics available on the total number of dead and cured people over the 10 years this therapy was deployed suggest that the outcomes were better in the subsequent years, possibly due to improvement of technique. As a consequence of this innovative research, which had as its principle reorganizing the central nervous system by using the seizure triggered by malaria fever, other forms of shock therapies were developed, such as insulin therapy, cardiazol shock therapy, and electroconvulsive therapy. 2014 artículo científico 2237-6089 https://www.redalyc.org/articulo.oa?id=311032220007 en http://www.redalyc.org/revista.oa?id=3110 Trends in Psychiatry and Psychotherapy application/pdf Associação de Psiquiatria do Rio Grande do Sul Trends in Psychiatry and Psychotherapy (Brasil) Num.3 Vol.36 |
| format | Artículo científico |
| id | redalyc_311032220007 |
| language | en |
| publishDate | 2014 |
| publisher | Associação de Psiquiatria do Rio Grande do Sul |
| spellingShingle | Profile of patients treated with malariotherapy in a psychiatric hospital in Porto Alegre, Brazil: a historical note Guilherme Astor Torres Psicología Wagner Jauregg Neurosyphilis malaria fever therapy Profile of patients treated with malariotherapy in a psychiatric hospital in Porto Alegre, Brazil: a historical note Guilherme Astor Torres Maria Helena Itaqui Lopes Edson Medeiros Cheuiche Luiz Gustavo Guilhermano Psicología Wagner Jauregg Neurosyphilis malaria fever therapy Introduction: Malariotherapy was a treatment to cure neurosyphilis developed in 1917 by Wagner-Jauregg, by inoculating blood infected with malaria in patients with neurosyphilis. The patient had febrile episodes that often cured him of the syphilitic infection. This treatment won the Nobel Prize in Medicine in 1927 and it was introduced in Hospital Psiquiátrico São Pedro (HPSP) in 1929. Methods: This is a descriptive retrospective cross-sectional study with collection of historical secondary data. Data were collected from a sample of 19 medical records of patients treated with malariotherapy in HPSP, in 1929 and 1930. Results: Most patients were white men aged from 25 to 40 years. The mean length of hospital stay was 1.4 year and the outcomes at this early application of malariotherapy were mostly negative (63.2% died). Discussion: The 19 cases evaluated in this study refer to the first year of application of malariotherapy in HPSP. The statistics available on the total number of dead and cured people over the 10 years this therapy was deployed suggest that the outcomes were better in the subsequent years, possibly due to improvement of technique. As a consequence of this innovative research, which had as its principle reorganizing the central nervous system by using the seizure triggered by malaria fever, other forms of shock therapies were developed, such as insulin therapy, cardiazol shock therapy, and electroconvulsive therapy. 2014 artículo científico 2237-6089 https://www.redalyc.org/articulo.oa?id=311032220007 en http://www.redalyc.org/revista.oa?id=3110 Trends in Psychiatry and Psychotherapy application/pdf Associação de Psiquiatria do Rio Grande do Sul Trends in Psychiatry and Psychotherapy (Brasil) Num.3 Vol.36 |
| title | Profile of patients treated with malariotherapy in a psychiatric hospital in Porto Alegre, Brazil: a historical note |
| topic | Psicología Wagner Jauregg Neurosyphilis malaria fever therapy |
| url | https://www.redalyc.org/articulo.oa?id=311032220007 |