THE DIAGNOSIS OF SCHISTOSOMIASIS IN MODERN AND ANCIENT TISSUES BY MEANS OF IMMUNOCYTOCHEMISTRY

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Main Author: Patricia Rutherford
Format: Artículo científico
Language:en
Published: Universidad de Tarapacá 2000
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author Patricia Rutherford
author_facet Patricia Rutherford
contents THE DIAGNOSIS OF SCHISTOSOMIASIS IN MODERN AND ANCIENT TISSUES BY MEANS OF IMMUNOCYTOCHEMISTRY Patricia Rutherford Antropología mummies Histology paleopathology paleoparasitology Although Schistosoma worms infect millions of people today they were evident in ancient Egyptian times, with one of the classic symptoms "haematuria" being described in various medical papyri. A current epidemiology study means diagnostic tools that can be applied to ancient dehydrated tissues are now needed. To overcome this immunocytochemistry has been used, producing positive staining to S. Mansoni and haematobium antigens in both modern and ancient tissues, suggesting that Schistosoma antigens may still be present after thousands of years. Initially, the presence of silica particles enmeshed within ancient tissues made sectioning difficult but this has been overcome by soaking the tissue in a weak solution of hydrofluoric acid which does not disrupt the epitopes whilst the silica dissolves. The application of Immunocytochemistry to ancient tissues has proved to be relatively cheap to perform and may prelude other more complicated tests 2000 artículo científico 0716-1182 https://www.redalyc.org/articulo.oa?id=32614411021 en http://www.redalyc.org/revista.oa?id=326 Chungara, Revista de Antropología Chilena application/pdf Universidad de Tarapacá Chungara, Revista de Antropología Chilena (Chile) Num.1 Vol.32
format Artículo científico
id redalyc_32614411021
institution Redalyc
language en
publishDate 2000
publisher Universidad de Tarapacá
spellingShingle THE DIAGNOSIS OF SCHISTOSOMIASIS IN MODERN AND ANCIENT TISSUES BY MEANS OF IMMUNOCYTOCHEMISTRY
Patricia Rutherford
Antropología
mummies
Histology
paleopathology
paleoparasitology
THE DIAGNOSIS OF SCHISTOSOMIASIS IN MODERN AND ANCIENT TISSUES BY MEANS OF IMMUNOCYTOCHEMISTRY Patricia Rutherford Antropología mummies Histology paleopathology paleoparasitology Although Schistosoma worms infect millions of people today they were evident in ancient Egyptian times, with one of the classic symptoms "haematuria" being described in various medical papyri. A current epidemiology study means diagnostic tools that can be applied to ancient dehydrated tissues are now needed. To overcome this immunocytochemistry has been used, producing positive staining to S. Mansoni and haematobium antigens in both modern and ancient tissues, suggesting that Schistosoma antigens may still be present after thousands of years. Initially, the presence of silica particles enmeshed within ancient tissues made sectioning difficult but this has been overcome by soaking the tissue in a weak solution of hydrofluoric acid which does not disrupt the epitopes whilst the silica dissolves. The application of Immunocytochemistry to ancient tissues has proved to be relatively cheap to perform and may prelude other more complicated tests 2000 artículo científico 0716-1182 https://www.redalyc.org/articulo.oa?id=32614411021 en http://www.redalyc.org/revista.oa?id=326 Chungara, Revista de Antropología Chilena application/pdf Universidad de Tarapacá Chungara, Revista de Antropología Chilena (Chile) Num.1 Vol.32
title THE DIAGNOSIS OF SCHISTOSOMIASIS IN MODERN AND ANCIENT TISSUES BY MEANS OF IMMUNOCYTOCHEMISTRY
topic Antropología
mummies
Histology
paleopathology
paleoparasitology
url https://www.redalyc.org/articulo.oa?id=32614411021