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| Format: | Artículo científico |
| Language: | en |
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Academia Brasileira de Ciências
2012
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| Online Access: | https://www.redalyc.org/articulo.oa?id=32721622019 |
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Table of Contents:
- A brief report on some health aspects of rats fed with crescent levels of recombinant chagasin, a potential plant defense protein Osmundo B. Oliveira Neto Davi F. Farias Ilka M. Vasconcelos Norma S. Paes Ana C. S. Monteiro Maria C. M. da Silva Luciane M. Guimarães Ana F.U. Carvalho Maria F. Grossi-de-Sá Multidisciplinaria (Ciencias Naturales y Exactas) short Chagasin hazard potential recombinant protein term rat feeding trial Chagasin may be considered a potential plant-incorporated protectant (PIP) protein due to its deleterious effects on insect pests. However, extensive safety studies with PIP's are necessary before introducing them into the target plant. Thus, a short-term feeding trial in rats with high doses of r-chagasin was conducted to provide evidences about its safety. Three test diets containing casein + r-chagasin (0.25, 0.5 and 1% of total protein) were offered to rats (10 days). The test diets did not show adverse effects upon the development, organ weight, hematological parameters and serum protein profiles of rats, providing preliminary information on the safety of r-chagasin. 2012 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32721622019 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.1 Vol.84