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| Format: | Artículo científico |
| Language: | en |
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Academia Brasileira de Ciências
2013
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| Online Access: | https://www.redalyc.org/articulo.oa?id=32725624010 |
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Table of Contents:
- Nanoparticle-based therapy for respiratory diseases ADRIANA L. DA SILVA RAQUEL S. SANTOS DÉBORA G. XISTO SILVIA DEL V. ALONSO MARCELO M. MORALES PATRICIA R.M. ROCCO Multidisciplinaria (Ciencias Naturales y Exactas) Asthma lung cancer turberculosis nanotechnology Nanotechnology is an emerging science with the potential to create new materials and strategies involving manipulation of matter at the nanometer scale (<100 nm). With size-dependent properties, nanoparticles have introduced a new paradigm in pharmacotherapy – the possibility of cell-targeted drug delivery with minimal systemic side effects and toxicity. The present review provides a summary of published findings, especially regarding to nanoparticle formulations for lung diseases. The available data have shown some benefits with nanoparticle-based therapy in the development of the disease and lung remodeling in respiratory diseases. However, there is a wide gap between the concepts of nanomedicine and the published experimental data and clinical reality. In addition, studies are still required to determine the potential of nanotherapy and the systemic toxicity of nanomaterials for future human use. 2013 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32725624010 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.1 Vol.85