Salvato in:
| Autore principale: | |
|---|---|
| Natura: | Artículo científico |
| Lingua: | en |
| Pubblicazione: |
Academia Brasileira de Ciências
2016
|
| Soggetti: | |
| Accesso online: | https://www.redalyc.org/articulo.oa?id=32746362017 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1866814170427555840 |
|---|---|
| author | NADA H. ALTWATY |
| author_facet | NADA H. ALTWATY |
| contents | Molecular and cytogenetic assessment of Dipterygium glaucum genotoxicity NADA H. ALTWATY OSAMA E. EL-SAYED NARIMAN A.H. ALY MOHAMED N. BAESHEN NABIH A. BAESHEN Multidisciplinaria (Ciencias Naturales y Exactas) Dipterygium glaucum three plant extracts protein and RAPD analyses cytogenetic on mitotic roots of Vicia faba The aim of the present study is to assess the genotoxicity of Dipterygium glaucum grows widely in Saudi Arabia desert to produce safety herbal products. This work is considered the first and pioneer report so far due to the lack and poor evaluated reports of the plant species for their mutagensity, genotoxicity and cytogenetics effects. Cytogenetic effects of D. glaucum on mitotic in roots of Vicia faba showed reduction in mitotic activity using three extracts; water, ethanol and ethyl acetate. Chromosomal abnormalities were recorded that included stickiness of chromosomes, chromatin bridge, fragments, lagging chromosome and micronuclei. Protein bands and RAPD analyses of V. faba treated with three D. glaucum extracts revealed some newly induced proteins and DNA fragments and other disappeared. Chemical constitution of the plant species should be identified with their biological activities against human and animal cells like HeLa cancer cell line. We are recommending using additional genotoxicity tests and other toxicity tests on animal culture with different concentrations and also utilizing several drought and heat tolerant genes of the plant species in gene cloning to develop and improve other economical crop plants instead of using the species as oral herbal remedy. 2016 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32746362017 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.1 Vol.88 |
| format | Artículo científico |
| id | redalyc_32746362017 |
| language | en |
| publishDate | 2016 |
| publisher | Academia Brasileira de Ciências |
| spellingShingle | Molecular and cytogenetic assessment of Dipterygium glaucum genotoxicity NADA H. ALTWATY Multidisciplinaria (Ciencias Naturales y Exactas) Dipterygium glaucum three plant extracts protein and RAPD analyses cytogenetic on mitotic roots of Vicia faba Molecular and cytogenetic assessment of Dipterygium glaucum genotoxicity NADA H. ALTWATY OSAMA E. EL-SAYED NARIMAN A.H. ALY MOHAMED N. BAESHEN NABIH A. BAESHEN Multidisciplinaria (Ciencias Naturales y Exactas) Dipterygium glaucum three plant extracts protein and RAPD analyses cytogenetic on mitotic roots of Vicia faba The aim of the present study is to assess the genotoxicity of Dipterygium glaucum grows widely in Saudi Arabia desert to produce safety herbal products. This work is considered the first and pioneer report so far due to the lack and poor evaluated reports of the plant species for their mutagensity, genotoxicity and cytogenetics effects. Cytogenetic effects of D. glaucum on mitotic in roots of Vicia faba showed reduction in mitotic activity using three extracts; water, ethanol and ethyl acetate. Chromosomal abnormalities were recorded that included stickiness of chromosomes, chromatin bridge, fragments, lagging chromosome and micronuclei. Protein bands and RAPD analyses of V. faba treated with three D. glaucum extracts revealed some newly induced proteins and DNA fragments and other disappeared. Chemical constitution of the plant species should be identified with their biological activities against human and animal cells like HeLa cancer cell line. We are recommending using additional genotoxicity tests and other toxicity tests on animal culture with different concentrations and also utilizing several drought and heat tolerant genes of the plant species in gene cloning to develop and improve other economical crop plants instead of using the species as oral herbal remedy. 2016 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32746362017 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.1 Vol.88 |
| title | Molecular and cytogenetic assessment of Dipterygium glaucum genotoxicity |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) Dipterygium glaucum three plant extracts protein and RAPD analyses cytogenetic on mitotic roots of Vicia faba |
| url | https://www.redalyc.org/articulo.oa?id=32746362017 |