Phytochemical Screening and Acute Toxicity of Aqueous Extract of Leaves of Conocarpus erectus Linnaeus in Swiss Albino Mice
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Academia Brasileira de Ciências
2016
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| _version_ | 1876483387619803136 |
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| author | DAYANE K.D. NASCIMENTO |
| author_facet | DAYANE K.D. NASCIMENTO |
| contents | Phytochemical Screening and Acute Toxicity of Aqueous Extract of Leaves of Conocarpus erectus Linnaeus in Swiss Albino Mice DAYANE K.D. NASCIMENTO IVONE A. DE SOUZA ANTÔNIO F.M. DE OLIVEIRA MARIANA O. BARBOSA MARLLON A.N. SANTANA DANIEL F. PEREIRA JÚNIOR EDUARDO C. LIRA JEYMESSON R.C. VIEIRA Multidisciplinaria (Ciencias Naturales y Exactas) Acute toxicity aqueous extract plants extracts medicinal plants Conocarpus erectus Mangroves represent areas of high biological productivity and it is a region rich in bioactive substances used in medicine production. Conocarpus erectus (Combretaceae) known as button mangrove is one of the species found in mangroves and it is used in folk medicine in the treatment of anemia, catarrh, conjunctivitis, diabetes, diarrhea, fever, gonorrhea, headache, hemorrhage, orchitis, rash, bumps and syphilis. The present study aimed to investigate the acute toxicity of aqueous extract of leaves of C. erectus in Swiss albino mice. The plant material was collected in Vila Velha mangroves, located in Itamaracá (PE). The material was subjected to a phytochemical screening where extractive protocols to identify majority molecules present in leaves were used. The evaluation of acute toxicity of aqueous extract of C. erectus followed the model of Acute Toxicity Class based on OECD 423 Guideline, 2001. The majority molecules were identified: flavonoids, tannins and saponins. The LD 50 was estimated at 2,000 mg/kg bw. Therefore, the aqueous extract showed low acute toxicity classified in category 5. 2016 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32746972022 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.3 Vol.88 |
| format | Artículo científico |
| id | redalyc_32746972022 |
| institution | Redalyc |
| language | en |
| publishDate | 2016 |
| publisher | Academia Brasileira de Ciências |
| spellingShingle | Phytochemical Screening and Acute Toxicity of Aqueous Extract of Leaves of Conocarpus erectus Linnaeus in Swiss Albino Mice DAYANE K.D. NASCIMENTO Multidisciplinaria (Ciencias Naturales y Exactas) Acute toxicity aqueous extract plants extracts medicinal plants Conocarpus erectus Phytochemical Screening and Acute Toxicity of Aqueous Extract of Leaves of Conocarpus erectus Linnaeus in Swiss Albino Mice DAYANE K.D. NASCIMENTO IVONE A. DE SOUZA ANTÔNIO F.M. DE OLIVEIRA MARIANA O. BARBOSA MARLLON A.N. SANTANA DANIEL F. PEREIRA JÚNIOR EDUARDO C. LIRA JEYMESSON R.C. VIEIRA Multidisciplinaria (Ciencias Naturales y Exactas) Acute toxicity aqueous extract plants extracts medicinal plants Conocarpus erectus Mangroves represent areas of high biological productivity and it is a region rich in bioactive substances used in medicine production. Conocarpus erectus (Combretaceae) known as button mangrove is one of the species found in mangroves and it is used in folk medicine in the treatment of anemia, catarrh, conjunctivitis, diabetes, diarrhea, fever, gonorrhea, headache, hemorrhage, orchitis, rash, bumps and syphilis. The present study aimed to investigate the acute toxicity of aqueous extract of leaves of C. erectus in Swiss albino mice. The plant material was collected in Vila Velha mangroves, located in Itamaracá (PE). The material was subjected to a phytochemical screening where extractive protocols to identify majority molecules present in leaves were used. The evaluation of acute toxicity of aqueous extract of C. erectus followed the model of Acute Toxicity Class based on OECD 423 Guideline, 2001. The majority molecules were identified: flavonoids, tannins and saponins. The LD 50 was estimated at 2,000 mg/kg bw. Therefore, the aqueous extract showed low acute toxicity classified in category 5. 2016 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32746972022 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.3 Vol.88 |
| title | Phytochemical Screening and Acute Toxicity of Aqueous Extract of Leaves of Conocarpus erectus Linnaeus in Swiss Albino Mice |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) Acute toxicity aqueous extract plants extracts medicinal plants Conocarpus erectus |
| url | https://www.redalyc.org/articulo.oa?id=32746972022 |