Surface, thermal and hemocompatible properties of novel single stage electrospun nanocomposites comprising polyurethane blended with bio oilTM

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Autore principale: MANIKANDAN AYYAR
Natura: Artículo científico
Lingua:en
Pubblicazione: Academia Brasileira de Ciências 2017
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author MANIKANDAN AYYAR
author_facet MANIKANDAN AYYAR
contents Surface, thermal and hemocompatible properties of novel single stage electrospun nanocomposites comprising polyurethane blended with bio oilTM MANIKANDAN AYYAR MOHAN PRASATH MANI SARAVANA KUMAR JAGANATHAN RAJASEKAR RATHINASAMY AHMAD ZAHRAN KHUDZARI NAVANEETHA PANDIYARAJ KRISHNASAMY Multidisciplinaria (Ciencias Naturales y Exactas) Bio oilTM Polyurethane Nanocomposite wound healing atomic force microscopy In this work, the physicochemical and blood compatibility properties of prepared PU/Bio oil nanocomposites were investigated. Scanning electron microscope (SEM) studies revealed the reduction of mean fiber diameter (709 ± 211 nm) compared to the pristine PU (969 nm ± 217 nm). Fourier transform infrared spectroscopy (FTIR) analysis exposed the characteristic peaks of pristine PU. Composite peak intensities were decreased insinuating the interaction of the bio oil TM with the PU. Contact angle analysis portrayed the hydrophobic nature of the fabricated patch compared to pristine PU. Thermal gravimetric analysis (TGA) depicted the better thermal stability of the novel nanocomposite patch and its different thermal behavior in contrast with the pristine PU. Atomic force microscopy (AFM) analysis revealed the increase in the surface roughness of the composite patch. Activated partial thromboplastin time (APTT) and prothrombin time (PT) signified the novel nanocomposite patch ability in reducing the thrombogenicity and promoting the anticoagulant nature. Finally the hemolytic percentage of the fabricated composite was in the acceptable range revealing its safety and compatibility with the red blood cells. To reinstate, the fabricated patch renders promising physicochemical and blood compatible nature making it a new putative candidate for wound healing application. 2017 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32753602039 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.3 Vol.89
format Artículo científico
id redalyc_32753602039
institution Redalyc
language en
publishDate 2017
publisher Academia Brasileira de Ciências
spellingShingle Surface, thermal and hemocompatible properties of novel single stage electrospun nanocomposites comprising polyurethane blended with bio oilTM
MANIKANDAN AYYAR
Multidisciplinaria (Ciencias Naturales y Exactas)
Bio oilTM
Polyurethane
Nanocomposite
wound healing
atomic force microscopy
Surface, thermal and hemocompatible properties of novel single stage electrospun nanocomposites comprising polyurethane blended with bio oilTM MANIKANDAN AYYAR MOHAN PRASATH MANI SARAVANA KUMAR JAGANATHAN RAJASEKAR RATHINASAMY AHMAD ZAHRAN KHUDZARI NAVANEETHA PANDIYARAJ KRISHNASAMY Multidisciplinaria (Ciencias Naturales y Exactas) Bio oilTM Polyurethane Nanocomposite wound healing atomic force microscopy In this work, the physicochemical and blood compatibility properties of prepared PU/Bio oil nanocomposites were investigated. Scanning electron microscope (SEM) studies revealed the reduction of mean fiber diameter (709 ± 211 nm) compared to the pristine PU (969 nm ± 217 nm). Fourier transform infrared spectroscopy (FTIR) analysis exposed the characteristic peaks of pristine PU. Composite peak intensities were decreased insinuating the interaction of the bio oil TM with the PU. Contact angle analysis portrayed the hydrophobic nature of the fabricated patch compared to pristine PU. Thermal gravimetric analysis (TGA) depicted the better thermal stability of the novel nanocomposite patch and its different thermal behavior in contrast with the pristine PU. Atomic force microscopy (AFM) analysis revealed the increase in the surface roughness of the composite patch. Activated partial thromboplastin time (APTT) and prothrombin time (PT) signified the novel nanocomposite patch ability in reducing the thrombogenicity and promoting the anticoagulant nature. Finally the hemolytic percentage of the fabricated composite was in the acceptable range revealing its safety and compatibility with the red blood cells. To reinstate, the fabricated patch renders promising physicochemical and blood compatible nature making it a new putative candidate for wound healing application. 2017 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32753602039 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.3 Vol.89
title Surface, thermal and hemocompatible properties of novel single stage electrospun nanocomposites comprising polyurethane blended with bio oilTM
topic Multidisciplinaria (Ciencias Naturales y Exactas)
Bio oilTM
Polyurethane
Nanocomposite
wound healing
atomic force microscopy
url https://www.redalyc.org/articulo.oa?id=32753602039