Susceptible hosts: a resort for parasites right in the eye of the immune response

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Autor principal: George A. Dosreis
Formato: Artículo científico
Lenguaje:en
Publicado: Academia Brasileira de Ciências 2000
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author George A. Dosreis
author_facet George A. Dosreis
contents Susceptible hosts: a resort for parasites right in the eye of the immune response George A. Dosreis Multidisciplinaria (Ciencias Naturales y Exactas) CTLA apoptosis T lymphocytes Trypanosoma cruzi Leishmania chagasi Trypanosomatid protozoan parasites express an aggressive strategy of parasitism by infecting hostmacrophages and inducing extensive T-lymphocyte activation. One goal of such strategy is to drive theimmune response of genetically susceptible hosts to a state of unresponsiveness regarding parasite killing.Unresponsiveness is achieved through different mechanisms, depending on the parasite species. In this briefreview, recent findings on the molecular and cellular bases of the parasites´ exploitation of host immuneresponses are discussed. 2000 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32772111 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.1 Vol.72
format Artículo científico
id redalyc_32772111
institution Redalyc
language en
publishDate 2000
publisher Academia Brasileira de Ciências
spellingShingle Susceptible hosts: a resort for parasites right in the eye of the immune response
George A. Dosreis
Multidisciplinaria (Ciencias Naturales y Exactas)
CTLA
apoptosis
T lymphocytes
Trypanosoma cruzi
Leishmania chagasi
Susceptible hosts: a resort for parasites right in the eye of the immune response George A. Dosreis Multidisciplinaria (Ciencias Naturales y Exactas) CTLA apoptosis T lymphocytes Trypanosoma cruzi Leishmania chagasi Trypanosomatid protozoan parasites express an aggressive strategy of parasitism by infecting hostmacrophages and inducing extensive T-lymphocyte activation. One goal of such strategy is to drive theimmune response of genetically susceptible hosts to a state of unresponsiveness regarding parasite killing.Unresponsiveness is achieved through different mechanisms, depending on the parasite species. In this briefreview, recent findings on the molecular and cellular bases of the parasites´ exploitation of host immuneresponses are discussed. 2000 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32772111 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.1 Vol.72
title Susceptible hosts: a resort for parasites right in the eye of the immune response
topic Multidisciplinaria (Ciencias Naturales y Exactas)
CTLA
apoptosis
T lymphocytes
Trypanosoma cruzi
Leishmania chagasi
url https://www.redalyc.org/articulo.oa?id=32772111