Functional role of a glycolipid in directional movements of neurons
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| Format: | Artículo científico |
| Language: | en |
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Academia Brasileira de Ciências
2001
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| _version_ | 1876468195302309888 |
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| author | Rosalia Mendez-Otero |
| author_facet | Rosalia Mendez-Otero |
| contents | Functional role of a glycolipid in directional movements of neurons Rosalia Mendez-Otero Marcelo F. Santiago Multidisciplinaria (Ciencias Naturales y Exactas) Glycolipid acetyl GD3 Ganglioside Development Neurite outgrowth Migration of neurons from their site of origin to their final destination is a critical and universal step in theformation of the complex structure of the nervous system. The migratory process is thought to be governed inpart by genetically and epigenetically defined sequences of signals which are interpreted by migrating cells.The molecular mechanisms that underlie neuronal migration have been the subject of intense investigation. Asin other developmental processes, many molecules must participate in neuronal migration. Some molecules,such as cell adhesion molecules and motor proteins, may contribute to discrete steps in the migration act;others, like extracellular signaling molecules, may regulate the activation and/or termination of the migrationprogram. In this article we review findings from our group that demonstrate the functional role(s) of a specificglycolipid in neuronal migration and neurite outgrowth in the developing and adult nervous system. 2001 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32773207 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.2 Vol.73 |
| format | Artículo científico |
| id | redalyc_32773207 |
| institution | Redalyc |
| language | en |
| publishDate | 2001 |
| publisher | Academia Brasileira de Ciências |
| spellingShingle | Functional role of a glycolipid in directional movements of neurons Rosalia Mendez-Otero Multidisciplinaria (Ciencias Naturales y Exactas) Glycolipid acetyl GD3 Ganglioside Development Neurite outgrowth Functional role of a glycolipid in directional movements of neurons Rosalia Mendez-Otero Marcelo F. Santiago Multidisciplinaria (Ciencias Naturales y Exactas) Glycolipid acetyl GD3 Ganglioside Development Neurite outgrowth Migration of neurons from their site of origin to their final destination is a critical and universal step in theformation of the complex structure of the nervous system. The migratory process is thought to be governed inpart by genetically and epigenetically defined sequences of signals which are interpreted by migrating cells.The molecular mechanisms that underlie neuronal migration have been the subject of intense investigation. Asin other developmental processes, many molecules must participate in neuronal migration. Some molecules,such as cell adhesion molecules and motor proteins, may contribute to discrete steps in the migration act;others, like extracellular signaling molecules, may regulate the activation and/or termination of the migrationprogram. In this article we review findings from our group that demonstrate the functional role(s) of a specificglycolipid in neuronal migration and neurite outgrowth in the developing and adult nervous system. 2001 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32773207 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.2 Vol.73 |
| title | Functional role of a glycolipid in directional movements of neurons |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) Glycolipid acetyl GD3 Ganglioside Development Neurite outgrowth |
| url | https://www.redalyc.org/articulo.oa?id=32773207 |