Voltammetric characteristics of miconazole and its cathodic stripping voltammetric determination
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| Format: | Artículo científico |
| Language: | en |
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Academia Brasileira de Ciências
2002
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| _version_ | 1876433188004298752 |
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| author | Francisco C. Pereira |
| author_facet | Francisco C. Pereira |
| contents | Voltammetric characteristics of miconazole and its cathodic stripping voltammetric determination Francisco C. Pereira Nelson R. Stradiotto Maria Valnice B. Zanoni Multidisciplinaria (Ciencias Naturales y Exactas) miconazole voltammetry determination electroanalysis Miconazole is reduced at mercury electrode above pH 6 involving organometallic compound formation,responsible for an anomalous polarographic behavior. The electrodic process presents a large contributionof the adsorption effects. The drug can be determined by cathodic stripping voltammetry from 8.0 × 10−8to 1, 5 × 10−6 mol L−1 in Britton-Robinson buffer pH 8.0, when pre-accumulated for 30 s at an accumulationpotential of 0V. A relative standard deviation of 3.8% was obtained for ten measurements of1.0 × 10−7 mol L−1 miconazole in B-R buffer pH 8.0 and a limit detection of 1, 7 × 10−8 mol L−1 wasdetermined using 60 s of deposition time and scan rate of 100 mV s−1. The proposed method is simple, preciseand it was applied successfully for the determination of the miconazole in pure form and in commercialformulations, showing mean recoveries of 99.798.4%. 2002 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32774305 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.3 Vol.74 |
| format | Artículo científico |
| id | redalyc_32774305 |
| institution | Redalyc |
| language | en |
| publishDate | 2002 |
| publisher | Academia Brasileira de Ciências |
| spellingShingle | Voltammetric characteristics of miconazole and its cathodic stripping voltammetric determination Francisco C. Pereira Multidisciplinaria (Ciencias Naturales y Exactas) miconazole voltammetry determination electroanalysis Voltammetric characteristics of miconazole and its cathodic stripping voltammetric determination Francisco C. Pereira Nelson R. Stradiotto Maria Valnice B. Zanoni Multidisciplinaria (Ciencias Naturales y Exactas) miconazole voltammetry determination electroanalysis Miconazole is reduced at mercury electrode above pH 6 involving organometallic compound formation,responsible for an anomalous polarographic behavior. The electrodic process presents a large contributionof the adsorption effects. The drug can be determined by cathodic stripping voltammetry from 8.0 × 10−8to 1, 5 × 10−6 mol L−1 in Britton-Robinson buffer pH 8.0, when pre-accumulated for 30 s at an accumulationpotential of 0V. A relative standard deviation of 3.8% was obtained for ten measurements of1.0 × 10−7 mol L−1 miconazole in B-R buffer pH 8.0 and a limit detection of 1, 7 × 10−8 mol L−1 wasdetermined using 60 s of deposition time and scan rate of 100 mV s−1. The proposed method is simple, preciseand it was applied successfully for the determination of the miconazole in pure form and in commercialformulations, showing mean recoveries of 99.798.4%. 2002 artículo científico 0001-3765 https://www.redalyc.org/articulo.oa?id=32774305 en http://www.redalyc.org/revista.oa?id=327 Anais da Academia Brasileira de Ciências application/pdf Academia Brasileira de Ciências Anais da Academia Brasileira de Ciências (Brasil) Num.3 Vol.74 |
| title | Voltammetric characteristics of miconazole and its cathodic stripping voltammetric determination |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) miconazole voltammetry determination electroanalysis |
| url | https://www.redalyc.org/articulo.oa?id=32774305 |